具有位相型随机补货提前期的PH退化可修系统及其最优更换策略

将几何过程与PH分布相结合, 讨论一个带有位相型随机补货提前期的PH退化可修系统.通过建立最小生成元$Q$矩阵,获得了系统在稳态情形下的状态概率分布向量及其数值解.根据上述研究结果同时也得到了系统的几个重要可靠性指标. 进一步地,还考虑了基于部件故障次数的订购策略和更换策略,导出系统单位时间平均运行成本的解析表达式并给出一个确定最优$N$策略的数值算例.     

Understanding the Influence of Phosphatidylcholine on the Molecular Weight of Hyaluronic Acid Synthesized by Streptococcus zooepidemicus

The effect of phosphatidylcholine on the molecular weight properties of hyaluronic acid (HA) was studied in batch culture of Streptococcus zooepidemicus by adding phosphatidylcholine at the early stage of exponential phase. With the addition of 80 mg/L of phosphatidylcholine, maximum HA yield (2.47 g/L) and weight-average molecular weight (902.60 KDa) were achieved, increased by 17.4% and 67.1%, respectively, as compared to the control. Metabolic flux analysis was employed to study the mechanism of phosphatidylcholine on the molecular weight of HA. The normalized flux distribution maps based on fermentation data at phosphatidylcholine addition indicated that phosphatidylcholine resulted in higher flux flowing to the HA pathway and lower flux flowing to the glycolysis and biomass synthesis pathway, coupling with higher level of UDPNAG generation and extra regeneration of ATP. The GC-MS analysis of fatty acids in the plasma membrane showed that the addition of phosphatidylcholine could promote the mobility and permeability of the cell membrane, making the HA chain pass through the membrane more easily, thus decreasing the energy consumption. All these results led to higher molecular weight of hyaluronic acid.     

关于半环上格林关系的开同余

首先给出了由半环的乘法半群上的格林关系所确定的半环开同余的性质和刻画.其次,由开同余出发,得到了六个不同的半环类,并证明了这六个半环类均是半环簇.最后,对半环簇的子簇格上的开算子进行了探讨,得到了一些有趣的结果.     

求解三维第一类Fredholm积分方程的GMRES法

利用数值求积公式,将三维第一类Fredholm积分方程进行离散,通过引入正则化方法,将离散后的积分方程转化为一离散适定问题,通过广义极小残余算法得到了其数值解．数值模拟结果表明该方法的可行有效性．     

Separation and identification of diarylheptanoids in supercritical fluid extract of Alpinia officinarum by UPLC-MS-MS

In the present study, ultra-performance liquid chromatography (UPLC) coupled to electrospray ionization (ESI(+)) tandem mass spectrometry (MS) was developed to identify and characterize the diarylheptanoids in the supercritical fluid extract (SFE) of Alpinia officinarum. The method established provides good reproducibility of UPLC and shows high precision with all the mass accuracy of less than 5 ppm. The ESI-MS-MS fragmentation behavior of every group and their appropriate characteristic pathways were proposed. On the basis of analyzing the fragmentation pathways, elemental composition provided by software Masslynx, mass data of the standard compounds and the information regarding polarity obtained from retention time data, in all, 23 diarylheptanods were characterized. All of them have been reported in Alpinia officinarum. They were classified into six distinct groups (homologous series). Compared to the references, the fragmentation pathways of the first and second group were detailed much more and complementary. Further more, the fragmentation pathways of the last four groups were firstly discussed. The fragmentation rules deduced and the data provided could aid in the characterization of other diarylheptanoids of these types and would be useful for the further research of diarylheptanoids in Alpinia officinarum or the other plants.