Beam-target double-spin asymmetry A{LT} in charged pion production from deep inelastic scattering on a transversely polarized {3}He target at 1.4<Q{2}<2.7 GeV{2}

We report the first measurement of the double-spin asymmetry A{LT} for charged pion electroproduction in semi-inclusive deep-inelastic electron scattering on a transversely polarized {3}He target. The kinematics focused on the valence quark region, 0.16相似文献   

Discretization orders for distance geometry problems

Given a weighted, undirected simple graph G = (V, E, d) (where \({d:E\to\mathbb{R}_+}\)), the distance geometry problem (DGP) is to determine an embedding \({x:V\to\mathbb{R}^K}\) such that \({\forall \{i,j\} \in E\;\|x_i-x_j\|=d_{ij}}\) . Although, in general, the DGP is solved using continuous methods, under certain conditions the search is reduced to a discrete set of points. We give one such condition as a particular order on V. We formalize the decision problem of determining whether such an order exists for a given graph and show that this problem is NP-complete in general and polynomial for fixed dimension K. We present results of computational experiments on a set of protein backbones whose natural atomic order does not satisfy the order requirements and compare our approach with some available continuous space searches.     

Ultrasensitive electrochemical detection of prostate-specific antigen (PSA) using gold-coated magnetic nanoparticles as 'dispersible electrodes'

Herein, we demonstrate the use of modified gold-coated magnetic nanoparticles as 'dispersible electrodes' which act as selective capture vehicles for electrochemical detection of prostate-specific antigen (PSA). A key advantage of this system is the ability to quantify non-electrochemical active analytes such as proteins with unprecedented detection limits and fast response times.     

Quality of Brazilian vegetable oils evaluated by (modulated) differential scanning calorimetry

Vegetable oils are increasingly replacing fossil-oil-based polymers, and therefore aimed at being used in polymerization reactions from ?20 to 100?°C. Therefore, phase transitions and heat capacities in this temperature range should be well characterized to optimize processing conditions and energy inputs. By using the DSC analysis, only small primary correspondence or divergence between different oil types are seen as a function of their degree of unsaturation, but it does not clearly distinguish detailed features such as shoulder bands related to the separate melting processes of single fatty acid components. By using modulated DSC analysis, the combined analysis of reversing and non-reversing heat signals provides better results. The latter confirms that the melting is not a physical one-step process, but equilibrates between phase transitions and enthalpic reorganizations of the fatty acids that can be monitored separately. The specific heat capacities measured during modulated DSC are somewhat lower than traditional calorimetric measurements, but relate to the degree of unsaturation. The thermal behavior of palm-, soy-, sunflower-, corn-, castor-, and rapeseed-oil is discussed in relation to their composition, by applying a first or second heating scan.     

Reformulations in mathematical programming: automatic symmetry detection and exploitation

If a mathematical program has many symmetric optima, solving it via Branch-and-Bound techniques often yields search trees of disproportionate sizes; thus, finding and exploiting symmetries is an important task. We propose a method for automatically finding the formulation group of any given Mixed-Integer Nonlinear Program, and for reformulating the problem by means of static symmetry breaking constraints. The reformulated problem—which is likely to have fewer symmetric optima—can then be solved via standard Branch-and-Bound codes such as CPLEX (for linear programs) and Couenne (for nonlinear programs). Our computational results include formulation group tables for the MIPLib3, MIPLib2003, GlobalLib and MINLPLib instance libraries and solution tables for some instances in the aforementioned libraries.     

The discretizable molecular distance geometry problem

Given a simple weighted undirected graph G=(V,E,d) with d:E???₊, the Molecular Distance Geometry Problem (MDGP) consists in finding an embedding x:V???³ such that ??x _u ?x _v ??=d _uv for each {u,v}??E. We show that under a few assumptions usually satisfied in proteins, the MDGP can be formulated as a search in a discrete space. We call this MDGP subclass the Discretizable MDGP (DMDGP). We show that the DMDGP is NP-hard and we propose a solution algorithm called Branch-and-Prune (BP). The BP algorithm performs remarkably well in practice in terms of speed and solution accuracy, and can be easily modified to find all incongruent solutions to a given DMDGP instance. We show computational results on several artificial and real-life instances.     

A dipole loudspeaker with a balanced directivity pattern

Analytical equations describing radiation characteristics of an oscillating ring in a circular finite baffle are derived, including the limiting case of a dipole point source at the center. An oscillating sphere would represent the ideal dipole source, having a constant directivity pattern at all frequencies, but would be inconvenient to realize especially in portable devices. It is found that a planar piston with uniform surface velocity but variable phase arranged to emulate the sphere does not have such a smooth on-axis response as the sphere. Instead a planar piston with the same phase distribution but uniform pressure represents an ideal planar source with a smooth on-axis response and near constant directivity. The surface velocity is plotted and it is then shown that a similar response can be achieved using a finite number of concentric rings based on this velocity distribution.     

A two-dimensional cochlear fluid model based on conformal mapping

Using conformal mapping, fluid motion inside the cochlear duct is derived from fluid motion in an infinite half plane. The cochlear duct is represented by a two-dimensional half-open box. Motion of the cochlear fluid creates a force acting on the cochlear partition, modeled by damped oscillators. The resulting equation is one-dimensional, more realistic, and can be handled more easily than existing ones derived by the method of images, making it useful for fast computations of physically plausible cochlear responses. Solving the equation of motion numerically, its ability to reproduce the essential features of cochlear partition motion is demonstrated. Because fluid coupling can be changed independently of any other physical parameter in this model, it allows the significance of hydrodynamic coupling of the cochlear partition to itself to be quantitatively studied. For the model parameters chosen, as hydrodynamic coupling is increased, the simple resonant frequency response becomes increasingly asymmetric. The stronger the hydrodynamic coupling is, the slower the velocity of the resulting traveling wave at the low frequency side is. The model's simplicity and straightforward mathematics make it useful for evaluating more complicated models and for education in hydrodynamics and biophysics of hearing.     

Diosphenol-based approach to the a-ring functionalization of advanced Taxol precursors

Several different approaches to the A-ring functionalization of an advanced, highly functionalized diosphenol precursor to Taxol are described. The first phase of the undertaking consists of an assessment of those reagents conducive to reaction at the enolic oxygen (silylation, methylation, allylation, and acylation). Transformations involving an alternative attack at the enol carbon center (bromination, selenation) have also been defined. Sodium borohydride reduction operates from the beta-face of C-14 as long as the C-1 hydroxyl is not protected so as to offer steric exclusion. Complications associated with various aspects of these methodological undertakings are addressed. The most advanced oxygenation achievements were realized by way of a noteworthy sequence involving epoxidation of the O-methyl ether, methanolysis under mildly acidic conditions, and regioselective oxidation of diol 38 to give 39.