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111.
Optical nonuniformities in the nuclear-pumped gas lasers are calculated. The nonuniformities are formed due to inhomogeneous energy deposition by the fission fragments from thin plane uranium layers that irradiate the laser active gas. The results of calculations agree with experimental data. 相似文献
112.
113.
Farrah Syazana Khattulanuar Mahendran Sekar Shivkanya Fuloria Siew Hua Gan Nur Najihah Izzati Mat Rani Subban Ravi Kumarappan Chidambaram M. Yasmin Begum Abul Kalam Azad Srikanth Jeyabalan Arulmozhi Dhiravidamani Lakshmi Thangavelu Pei Teng Lum Vetriselvan Subramaniyan Yuan Seng Wu Kathiresan V. Sathasivam Neeraj Kumar Fuloria 《Molecules (Basel, Switzerland)》2022,27(3)
Cardiovascular disorders (CVDs) are the leading risk factor for death worldwide, and research into the processes and treatment regimens has received a lot of attention. Tilianin is a flavonoid glycoside that can be found in a wide range of medicinal plants and is most commonly obtained from Dracocephalum moldavica. Due to its extensive range of biological actions, it has become a well-known molecule in recent years. In particular, numerous studies have shown that tilianin has cardioprotective properties against CVDs. Hence, this review summarises tilianin’s preclinical research in CVDs, as well as its mechanism of action and opportunities in future drug development. The physicochemical and drug-likeness properties, as well as the toxicity profile, were also highlighted. Tilianin can be a natural lead molecule in the therapy of CVDs such as coronary heart disease, angina pectoris, hypertension, and myocardial ischemia, according to scientific evidence. Free radical scavenging, inflammation control, mitochondrial function regulation, and related signalling pathways are all thought to play a role in tilianin’s cardioprotective actions. Finally, we discuss tilianin-derived compounds, as well as the limitations and opportunities of using tilianin as a lead molecule in drug development for CVDs. Overall, the scientific evidence presented in this review supports that tilianin and its derivatives could be used as a lead molecule in CVD drug development initiatives. 相似文献
114.
Gizem Gülsoy Toplan Turgut Takn Gkalp can Fatih Gger Mine Kürküolu Aye Civa Gülay Ecevit-Gen Afife Mat Kemal Hüsnü Can Baer 《Molecules (Basel, Switzerland)》2022,27(6)
The potential applications of Achillea species in various industries have encouraged the examination of their phytochemical components along with their biological potential. In the present study, phenolic contents and essential oil compositions together with the in vitro biological activities of the aerial parts from Achillea biebersteinii Afan. and Achillea millefolium subsp. millefolium Afan. collected from Turkey were evaluated. Different solvent extracts (n-hexane, chloroform, methanol, water) were prepared and their antimicrobial, anticholinesterase, and antioxidant activities were studied. The LC-MS/MS results revealed the presence of 16 different phenolic compounds, including chlorogenic acid, rutin, quercetin, and luteolin glycosides, in methanolic extracts. According to GC-FID and GC/MS results, the primary components of the oils were identified as 1,8-cineole (32.5%), piperitone (14.4%), and camphor (13.7%) in A. biebersteinii and 1,8-cineole (12.3%) and β-eudesmol (8.9%) in A. millefolium subsp. millefolium. The infusion and methanolic extracts of both species were found to be rich in their total phenolic content as well as their antioxidant and anticholinesterase activity. In contrast, the n-hexane and chloroform extracts of both species showed strong antimicrobial activity with MIC values ranging from 15 to 2000 μg/mL. Our findings suggest that the investigated Achillea species could be evaluated as potent natural agents, and further studies into the promising extracts are needed. 相似文献
115.
E. Drechsel O. Kallauner J. Matějka J. H. Chesters 《Analytical and bioanalytical chemistry》1939,117(9-10):379-379
116.
Transitivity and Chaos 总被引:1,自引:0,他引:1
Mat Jiehua 《东北数学》1998,(1)
Several different definitions of transitivity and their relationship are carefullydiscussed for general spaces, and it is proved that a continuous map on a metric space ischaotic in the sense of Devaney if and only if it is periodic orbit transitive or periodic orbitstrongly transitive. 相似文献
117.
J.?M.?MatíasEmail author W.?González-Manteiga M.?Francisco-Fernández C.?Ordó?ez 《Journal of Mathematical Modelling and Algorithms》2005,4(3):237-252
In this work, we apply variographic techniques from spatial statistics to the problem of model selection in local polynomial
regression with multivariate data. These techniques permit selection of the kernel and smoothing matrix with less computational
load and interpretation of the regularity of the regression function in different directions. Moreover, they may represent
the only feasible alternative for problems of a certain dimensionality. 相似文献
118.
We find and characterize an excitability regime mediated by localized structures in a dissipative nonlinear optical cavity. The scenario is that stable localized structures exhibit a Hopf bifurcation to self-pulsating behavior, that is followed by the destruction of the oscillation in a saddle-loop bifurcation. Beyond this point there is a regime of excitable localized structures under the application of suitable perturbations. Excitability emerges from the spatial dependence since the system does not exhibit any excitable behavior locally. We show that the whole scenario is organized by a Takens-Bogdanov codimension-2 bifurcation point. 相似文献
119.
120.
P. G. Thirolf D. Gassmann D. Habs M. Hunyadi A. Krasznahorkay E. Mergel H. Hübel D. Pansegrau D. Schwalm M. J. Chromik M. Csatlós J. Domscheit Y. Eisermann T. Faestermann G. Graw A. Görgen J. Gulyás K. Hauschild R. Hertenberger T. Härtlein F. Köck A. Lopez-Martens Z. Maté H. J. Maier A. Metz S. Neumann A. Neusser P. Reiter G. Schönwasser H. Scheit 《Acta Physica Hungarica A》2003,18(2-4):317-322
Progress in the experimental techniques used to investigate superdeformed fission isomers in the actinides allowed for detailed spectroscopic results of collective properties as well as for the identification of the rotational structure of multiphonon vibrational excitations. A novel approach could be established to determine the depth of the second potential well. 相似文献