Synthesis and mass spectra of some phosphadipeptides

Conclusions The mass-spectrometric fragmentation of several phosphadipeptides has been investigated. The mass spectra show peaks which are unequivocally related to the sequence of amino acid residues in the molecule, as well as peaks which correspond to the C-terminal amino acids. These peaks can be utilized for the massspectrometric identification of metabolites of the compounds studied.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 5, pp. 1138–1144, May, 1978.     

Reactions of diene hydrocarbons with nitroso-compounds addition of cyclohexa-1,3-diene to nitrosobenzene

1. 1.
   The reaction between cyclohexa-1,3-diene and nitrosobenzene has been studied.     

New amidoesters of thiophosphoric acid

The Todd-Atherton reaction of dialkyl thiophosphonates orO-alkyl piperididothiophosphonates with monoethanolamine vinyl ether afforded the corresponding amidoesters of thiophosphoric acid. Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 9, pp. 1876–1877, September, 1998.     

Esters of 1-phosphorus-substituted cyclopropanecarboxylic acids

Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 9, pp. 2150–2151, September, 1989.     

Synthesis of thiophosphoryl-substituted derivatives of cycloalkanecarboxylic acids

The 1-thiophosphorylated esters and nitriles of cycloalkanecarboxylic acids were obtained both by the direct reaction of derivatives of thiophosphorylacetic acids with ,-dihalogenoalkanes in the K₂CO₃/DMSO heterophasic system, and as a result of the reaction of the corresponding oxygen compounds with the Louson reagent.A. N. Nesmeyanov Institute of Heteroorganic Compounds, Russian Academy of Sciences, 117813 Moscow. Translated from Izvestiya Akademii Nauk, Seriya Khimicheskaya, No. 2, pp. 391–397, February, 1992.     

Structural features and the nature of the hydrogen bond in the enol form of α-diphenylphosphoryl-α-acetylacetonitrile based on X-ray diffraction data

It has been established by X-ray structural analysis that pure -diphenylphosphoryl--acetylacetonitrile exists in the enol form (aZ isomer). In crystals, a strong intramolecular P=O...H...O hydrogen bond is formed; the O...O distance is 2.551 Å. It has been demonstrated that the H atom is characterized by a high lability along the hydrogen bond, which exhibits a covalent component in the H...O region.Deceased.Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 8, pp. 1520–1524, August, 1995.The X-ray structural study was supported by the American Crystallography Association and the International Science Foundation (Grant No. M1F000).     

Synthesis of 2-keto-4-phosphorylbutyric acids and their derivatives

The Claisen condensation of 3-phosphorylated propionitriles with diethyl oxalate has been examined. The product of the condensation of 3-(methylethoxyphosphinyl)propionitrile, following hydrolysis, has been shown to be the enol form (Z-isomer) of 4-(methylhydroxyphosphinyl)-3-cyano-2-ketoburyric acid. On crystallization from water, the other isomers (the E-isomer of the enol or the keto-forms) were not isolated. Distillation of the products of silylation of the reaction mixture with hexamethyldisilazane gave both geometric isomers of the enol (Z and E). In aqueous solution, the enol gradually cyclizes to give 2-hydroxy-3-(methylhydroxyphosphinyl)citraconimide.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 9, pp. 2120–2127, September, 1990.