Helium-4 Bose fluids formed in one-dimensional 18 A diameter pores

Bose fluids restricted in one dimension (1D) are realized by adsorbing 4He atoms on the 1D pore walls with a diameter of about 18 A. The Bose fluid appears above an adsorbed amount after the pore walls are coated with the inert 4He atoms. Heat capacity of the fluid was observed to have a temperature-linear term at low temperatures. This corresponds to the phonon heat capacity of the Bose fluid in the 1D pores. We estimate the phonon velocity and the interaction of the 1D Bose fluid.     

Strength characteristics of the self-sustained wave in grooved channels with different groove length

The self-sustained oscillations arising in a series of grooved channels are investigated experimentally. Pressure drop, time-averaged and time-various local pressure in the grooved channels with six kinds of groove length are measured with the differential transducer and the pressure sensor, respectively, and the flow structures are visualized using the aluminum dust method. The local pressure signal shows that the self-sustained wave appears in the first or second frequency, and the Strouhal number, based on the nature frequency of the self-sustained wave, is almost equivalent for the first or second frequency in the same channel. Meanwhile, the Strouhal number for each channel decreases monotonously with the groove length. Furthermore, it is found that increasing pressure will result in higher amplitude of the self-sustained wave, this behavior is significant for the efficient heat transfer in practical engineering.     

Test compounds for detecting the silanol effect on the elution of ionized amines in reversed‐phase LC

The effectiveness of several basic compounds for testing silica‐based stationary phases was reviewed by applying them to recent columns for reversed‐phase HPLC. Most octadecylsilylated (C18) stationary phases, prepared as a base‐deactivated material from high‐purity silica gel with endcapping, provided excellent peak shape and column efficiency for the bases including benzylamine and amitriptyline that once caused problems and were subsequently employed for testing silanol activities. However, a cyclic tertiary amine, dextrometorphan, was eluted as an acceptable peak from only a few columns at neutral pH. Such a more sensitive probe is expected to contribute to further improvement of the stationary phase for reversed‐phase HPLC.     

The fatigue of aluminum alloys subjected to random loading

This paper describes an expeirmental investigation which was carried out to determine the fatigue life of two aluminum alloys (2024-T3 and 6061-T6). They were subjected to both constant-strain-amplitude sinusoidal and narrow-band random-strain-amplitude fatigue loadings. The fatigue-life values obtained from the narrow-band random testing were compared with theoretical predictions based on Miner's linear accumulation of damage hypothesis. Cantilever-beam-test specimens fabricated from the aluminum alloys were subjected to either a constant-strain-amplitude sinusoidal or a narrow-band random base excitation by means of an electromagnetic vibrations exciter. It was found that the ε-N curves for both alloys could be approximated by three straight-line segments in the low-, intermediate- and high-cycle fatigue-life ranges. Miner's hypothesis was used to predict the narrow-band random fatigue lives of materials with this type of ε-N behavior. These fatigue-life predictions were found to consistently overestimate the acutal fatigue lives by a factor of 2 or 3. However, the shape of the predicted fatigue-life curves and the high-cycle fatigue behavior of both materials were found to be in good agreement with the experimental results.     

Bisphenol A-recognition polymers prepared by covalent molecular imprinting

A specific recognition material for bisphenol A (BPA) was prepared by using a covalent imprinting technique. A chloroform solution containing bisphenol A dimethacrylate as a template, ethylene glycol dimethacrylate as a cross-linking agent and 2,2′-azobis(isobutyronitrile) as an initiator was polymerized by UV initiation. When BPA was removed from the resulting polymer by hydrolysis of the ester bonds with aqueous sodium hydroxide, carboxylic acid residues were generated in the polymer. After the polymer was packed into a stainless steel column, retention factors of BPA and related compounds were measured. The imprinted polymer adsorbed BPA and structurally related compounds such as 4,4′-dihydroxybenzophenone, bis(4-hydroxyphenyl)sulfone and 4,4′-dihydroxybiphenyl. A typical association constant (K_a) was calculated to be 1.72×10⁵ M⁻¹ by Scatchard analysis. Interestingly, 17α- and 17β-estradiol were also bound to the imprinted polymer (K_a=1.68×10⁵ M⁻¹), indicating that the polymer could be used as artificial receptors for screening the compounds having estrogenic action.     

Solid-phase synthesis of 2,3-diphenylpropionic acid library as VLA-4 antagonists

2,3-Diphenylpropionic acid library for VLA-4 antagonist was synthesized on solid-phase. Comparison of the two synthetic routes via an orthogonal generation of two aromatic amino functional groups are discussed. From this work, several compounds were identified as potent VLA-4 antagonists.