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91.
Maryam I. Daneshvar Guillermo A. Casay Gabor Patonay Malgorzata Lipowska Lucjan Strekowski Lawrence Evans III Leila Tarazi Abraham George 《Journal of fluorescence》1996,6(2):69-75
The design and application of a fluorescent fiber-optic immunosensor (FFOI) are reported. The FFOI is utilized for the detection of antibody/antigen binding within the near-infrared (NIR) spectral region. The technique is developed through the combined use of fiber-optic, semiconductor laser-excitation, fluorescence detection, NIR dye, and immunochemical techniques. The antibody is immobilized on the FFOI and utilized as a recognition component for trace amounts of specific antigen. The FFOI is constructed to utilize an antibody sandwich technique. The assay involves the immobilization of the capture antibody on the sensing tip of the FFOI followed by the exposure of the immobilized sensing tip to the antigen. The antigen-coated FFOI is then introduced to a second antibody previously labeled with the NIR dye. Typical measurements are performed in about 15 min. A semiconductor laser provides the excitation (780 nm) of the immune complex. The resulting emission is detected by a silicon photodiode detector (820 nm). The intensity of the resulting fluorescence is directly proportional to the concentration of the antigen. The sensitivity of the analysis reaches 10 ng/ml and the response time is 10–15 min. 相似文献
92.
Maryam?FaizEmail author Laia?Acarin Bernardo?Castellano Berta?Gonzalez 《BMC neuroscience》2005,6(1):26
Background
The forebrain subventricular zone (SVZ)-olfactory bulb pathway and hippocampal subgranular zone (SGZ) generate neurons into adulthood in the mammalian brain. Neurogenesis increases after injury to the adult brain, but few studies examine the effect of injury on neural and glial precursors in the postnatal brain. To characterize the spatio-temporal dynamics of cell proliferation in the germinative zones, this study utilized a model of postnatal damage induced by NMDA injection in the right sensorimotor cortex at postnatal day 9. 相似文献93.
Shi W Shafaei-Fallah M Anson CE Rothenberger A 《Dalton transactions (Cambridge, England : 2003)》2005,(24):3909-3912
The investigation presents new synthetic methods for the generation of tripodal P/S ligands by reactions of metal alkoxides and carboxylates with the organoperthiophosphinic acid anhydride Lawesson's reagent. Four new transition-metal complexes containing various tripodal ligand sets were synthesised and characterised. 相似文献
94.
This paper studies the stationary nonlinear Boltzmann equation for hard forces, in a Couette setting between two coaxial, rotating cylinders with given indata of Maxwellian type on the cylinders. A priori estimates are obtained mainly in L2, leading to multiple, isolated solutions together with a hydrodynamic limit control, based on asymptotic expansions together with a rest term. 相似文献
95.
Ansari M Kazemipour M Khosravi F Baradaran M 《Chemical & pharmaceutical bulletin》2004,52(10):1166-1170
Losartan, a highly effective blood pressure-lowering agent, has been widely used for the treatment of hypertension. A fast and reliable method for the determination of losartan was highly desirable to support formulation screening and quality control. A first-derivative UV spectroscopic method and HPLC were developed for the determination of losartan in the tablet dosage form. The first-derivative spectrum recorded between 220 and 320 nm and a zero-crossing technique for first-derivative measurement at 232.5 nm were selected. The selectivity and sensitivity of the method was in desirable range. In comparison with the direct UV method, first-derivative UV spectroscopy has a definite trough without any interference from UV absorbing-excipients. This method is also fast and economical in comparison with the more time-consuming HPLC method regularly used for formulation screening and quality control and can be used routinely by any laboratory possessing a spectrophotometer with a derivative accessory. The linear concentration ranges were 2-50 microg ml(-1), (D(1)=-0.0159C-0.0056, r=0.9994, n=6). Between-days CV of < or =2.9%, within-day CV of < or =2.1%, and analytical recovery close to 98.1% show the suitability of the method for determination in quality control. 相似文献
96.
Oxidation of Aromatic Amines to Quinones by Iodic Acid under Microwave Irradiation in the Presence of Montmorillonite K10 and Silica Gel 总被引:1,自引:0,他引:1
Mohammed M.?HashemiEmail author Maryam?Akhbari 《Monatshefte für Chemie / Chemical Monthly》2003,134(12):1561-1563
Summary. A variety of aromatic amines are oxidized to their corresponding quinones in excellent yields by supported iodic acid under microwave irradiation and solvent free conditions. 相似文献
97.
98.
Issa Yavari Maryam Sabbaghan Zinatossadat Hossaini Majid Ghazanfarpour‐Darjani 《Helvetica chimica acta》2008,91(6):1144-1147
Triphenyl phosphite reacts smoothly with dialkyl acetylenedicarboxylates and hexachloroacetone to produce alkyl 2‐(dichloromethylene)‐2,5‐dihydro‐5‐oxo‐4‐(trichloromethyl)furan‐3‐carboxylates in good yields. 相似文献
99.
An efficient experimentally simple and inexpensive catalyst system for the selective amidation of aryl iodides using 15 mol% of CuI as catalyst, 15 mol% of L-proline as ligand and KF/Al2O3 as a base in toluene is described. 相似文献
100.
A dynamic kinetic model for the oxidation of phenol in water by an UV/H2O2 process is developed. The model is based on the elementary chemical and photochemical reactions, initiated by the photolysis of hydrogen peroxide into hydroxyl radicals. The model is validated by using experimental data obtained from the open literature for an actual UV/H2O2 process. Using those data and the developed kinetic model, kinetic rate constants for phenol intermediates, catechol and hydroquinone, are estimated. Moreover, the optimum initial hydrogen peroxide concentration is estimated by means of the validated model. © 2007 Wiley Periodicals, Inc. Int J Chem Kinet 40: 34–43, 2008 相似文献