Liquid-Phase Synthesis of Methyl （2Z）-2-Arylsulfonylmethyl-2-alkenoates from PEG-Supported a-Phenylselenopropionate

Treatment of lithio derivativ e of novel PEG-supported a-phenylselenopropionate with aldehydes, followed by oxidation-elimination with 30% hydrogen peroxide, formed Baylis-Hillman products, which were then reacted with sodium arylsulfinate. The resulting sulfonylated products were cleaved from the PEG efficiently affording methyl （2Z）-2-arylsulfonylmethyl-2-alkenoates in good yields and high purities.     

PEO基纳米复合聚合物电解质电化学性质的研究

以PEO8 LiClO4作母体,纳米SiO2为填料,制成PEO8 LiClO4 SiO2(x%)系列复合聚合物电解质,测定这该电解质的电导率、锂离子迁移数和电化学稳定窗口,并对其晶态结构作差热分析表征.结果表明,纳米SiO2的引入,显著提高了电解质的电导率,在22℃时达到4.3×10-5S·cm-1.此外,还探讨了填料对复合聚合物电解质电导率提高的影响机理.     

化学类专业发展战略研究报告(草案)

1化学学科发展的历史沿革1661年,波义耳在其著名论文《怀疑派的化学家》中提出“元素”的概念,从而把化学确定为一门学科。1803年道尔顿提出了原子论,1811年阿伏加德罗提出了“分子”的概念,1860年康尼查罗提出了原子-分子论,经历了这些重要的发展阶段,到1870年门捷列夫发现了元素周期律,奠定了化学学科的理论基础。19世纪末,化学的重要分支学科分析化学、无机化学、有机化学和物理化学相继建立,这种分工大大推动了化学研究的深化。进入20世纪后,量子力学的诞生,近邻学科特别是数学、物理学和生物学的发展,以及各种新的实验技术及精密仪器的…     

Water-soluble phosphate-functionalized polyfluorene as fluorescence biosensors toward cytochrome c

An anionic water-soluble polyfluorene derivative, poly(9,9-bis(6′-phosphatehexyl)fluorene-alt-1,4-pheny lene) sodium salt (PFHPNa), was synthesized by Suzuki coupling reaction in DMF/water. Polymer PFHPNa was well soluble in water with a strong blue fluorescence emission. Effect of the side chain length on fluorescence sensory properties was studied by comparing quenching efficiencies toward different quenchers of PFHPNa with a reported polymer poly(9,9-bis(3′-phosphatepropyl)fluorene-alt-1,4-phenylene) sod...     

Synthesis and biological evaluation of ~(99m)Tc-HEDTA/HYNIC-MPP4 complex for 5-HT1A receptor imaging

5-HT1A receptor is associated with a variety of pathophysiology of neuropsychiatric disorders. Accordingly, we have synthesized a new 5-HT1A receptor ligand (HYNIC-MPP4) and labeled it with 99mTc using N-(2-hydroxyethyl)ethylenediaminetriacetic acid (HEDTA) as coligand. 99mTc-HEDTA/HYNIC-MPP4 was prepared under pH 6 at room temperature. Biodistribution of 99mTc-HEDTA/HYNIC-MPP4 in normal mice showed that this complex had moderate brain uptake (0.60% ID·g-1 at 2 min p.i.) and good retention. The hippocampus ...     

Synthesis, Crystal Structure and Magnetic Properties of a New 3D Cobalt Vanadate

A new cobalt vanadate compound 1 [Co^Ⅱ(H2O)2V2^VO6] has been hydrothermally synthesized and characterized by the elemental analyses and the single crystal X-ray diffraction analysis. Compound 1 crystallizes in the orthorhombic system, space group Pinna, with a=0.55646, b=1.06900, c=1.18452 nm, and Z=4. The magnetic susceptibility of the cobalt vanadate has been measured and indicates possible antiferromagnetic coupling between adjacent cobalt (Ⅱ) (0.5432—0.5697 nm) through bond or space.     

CRYSTAL AND MOLECULAR STRUCTURE OF O,O-DI-ISO-PROPYL-α-(1, 3, 4, 6-TETRA-O-ACETYL-2-DEOXY-β-D-GLU- COPYRANOSYL ) AMINO-α-p-METHYLPHENYLMETHYLPHOS-PHONATE

<正> The crystal C28H42O12NP is the monoclinic space group P21, with a = 10. 158(1), b=9. 069(1), c=18. 147(3) A , β=90. 72(1)% V=1671. 6 A3, Mr=615. 61, Z=2, Dx=1.23 g/cm3, μ=2.16 cm-1, F(000) = 660. The final R = 0. 071 and Rw = 0. 073 for 1860 observed reflections [I≥3σ(I)]. The results of structure analysis indicate that the configuration of the chiral carbon atom C(41) formed in the reaction is R *.     

激光驱动内爆低产额中子探测

采用新研制的BF_3计数管阵列测量激光驱动(包括间接驱动和混合驱动)充DT玻璃微球靶内爆中子产额。着重介绍BF_3计数管阵列的设计及特点,高压门电路的研制和1990年在上海“神光”装置上的测量结果。     

氢化物发生-原子荧光光谱法测定中草药中的硒

本文建立了氢化物发生-原子荧光光谱法测定中草药中的微量硒的分析方法。研究了仪器的工作条件、试剂对硒原子荧光强度的影响及硒(Ⅵ)的还原条件,探讨了共存离子对硒测定的干扰和消除方法,方法的检出限为0.21μg·L~(-1)。利用本方法成功地测定了10种中草药中的微量硒,回收率为95％～105％。方法简便、快速、灵敏、准确。     

某些二茂铁丙烯酰胺的结构与红外光谱特征

总结归属了6种N-烷基二茂铁丙烯酰胺及13种N-芳基二茂铁丙烯酰胺的主要红外吸收谱带和特征,讨论了其红外吸收频率随化合物结构变化的规律。结果表明,氮上取代基从空间效应及电子效应两方面影响化合物红外吸收,主要是对v c-c,v c-o及酰胺Ⅱ带有较大影响。