Reactions of chlorodithiophosphoric acid pyridiniumbetaine, py.PS
2Cl (
I) with 1-aminoadamantane (amantadine,
Am) and 1-amino-3,5-dimethyladamantane (memantine,
Mem), 1-(adamant-1-yl)ethylamine (rimantadine,
Rim), and 1-aminomethyladamantane (
amAd) were studied. New compounds –
N,
N′,
N′′,
N′′′-
tetrakis(adamant-1-yl)trithiophosphoric acic tetraamide (
II),
N,
N′,
N′′,
N′′′-
tetrakis(3,5-dimethyladamant-1-yl)trithiophosphoric acid tetraamide (
III), chlorodithiophosphoric acid 1-(adamant-1-yl)ethylamide pyridiniumbetaine (
IV), pyridinium salt of 1,3-
bis(adamant-1-yl)ethane-2,4-mercapto-2,4-dithioxo-1,3-diaza-2λ
5,4λ
5-diphosphetidine (
V),
N,
N′,
N′′,
N′′′-
tetrakis(adamant-1-ylmethyl)trithiophosphoric acid tetraamide (
VI), and pyridinium salt of 1,2-bis(adamant-1-ylmethane)-4-mercapto-2,4-dithioxo-1-aza-3-thia-2λ
5,4λ
5-diphosphetidine (
VII) – were prepared and characterized either/or by
31P NMR and infrared spectroscopy, the substances
II a
IV by X-ray diffraction analysis,
III,
V,
VI,
VII by MALDI TOF MS.
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