全文获取类型
收费全文 | 337篇 |
免费 | 6篇 |
国内免费 | 1篇 |
专业分类
化学 | 222篇 |
晶体学 | 35篇 |
力学 | 3篇 |
数学 | 19篇 |
物理学 | 65篇 |
出版年
2022年 | 3篇 |
2021年 | 4篇 |
2019年 | 4篇 |
2018年 | 3篇 |
2017年 | 3篇 |
2016年 | 5篇 |
2014年 | 4篇 |
2013年 | 8篇 |
2012年 | 7篇 |
2011年 | 8篇 |
2010年 | 6篇 |
2009年 | 6篇 |
2008年 | 10篇 |
2007年 | 10篇 |
2006年 | 9篇 |
2005年 | 11篇 |
2004年 | 6篇 |
2003年 | 8篇 |
2002年 | 5篇 |
2001年 | 11篇 |
2000年 | 15篇 |
1999年 | 18篇 |
1998年 | 6篇 |
1997年 | 8篇 |
1996年 | 13篇 |
1995年 | 15篇 |
1994年 | 7篇 |
1993年 | 9篇 |
1992年 | 4篇 |
1991年 | 3篇 |
1990年 | 13篇 |
1989年 | 13篇 |
1988年 | 8篇 |
1987年 | 7篇 |
1986年 | 3篇 |
1985年 | 3篇 |
1984年 | 9篇 |
1983年 | 2篇 |
1982年 | 6篇 |
1981年 | 5篇 |
1980年 | 2篇 |
1979年 | 2篇 |
1978年 | 6篇 |
1977年 | 12篇 |
1976年 | 3篇 |
1975年 | 3篇 |
1974年 | 3篇 |
1973年 | 3篇 |
1880年 | 2篇 |
1865年 | 2篇 |
排序方式: 共有344条查询结果,搜索用时 15 毫秒
131.
132.
Marchand E Atemnkeng MA Vanermen S Plaizier-Vercammen J 《Biomedical chromatography : BMC》2008,22(5):454-459
Owing to the development of parasite resistance to standard antimalarial treatments like chloroquine and sulfadoxine-pyrimethamine, the demand for Artemisia annua, a key ingredient for new and highly effective antimalarial drugs, is huge. Therefore selective and precise methods to determine the content of artemisinin in dry plant material and in raw impure extracts are needed. In this work a method is described for the clear separation and extraction of artemisinin from other plant components in the Artemisia annua L. plant by thin-layer chromatography (TLC). To obtain optimal extraction and recovery efficiency, several parameters were evaluated, including choice of extraction solvent, TLC plate type and sensitivity between UV and visible light. Method validation was performed on both the dry plant material and non-purified plant extracts. Toluene presented the highest extraction efficiency compared with petroleum ether, hexane and methanol. Reversed-phase plates showed more concentrated spots than normal-phase plates, while the sensitivity of the analysis in UV was comparable to that in visible light but less precise. The impure plant extracts were analyzed by both TLC and HPLC-UV at 215 nm and both methods met the requirements for linearity, selectivity, precision and accuracy. Hence, the proposed TLC method can easily be used for both qualitative and quantitative control of the raw plant extract in areas where advanced methods are scarce. 相似文献
133.
Some alkylsilica columns carry a positive charge at low pH, as determined by anion-exchange with nitrate ion. In the present study, the relative positive charge for 14 alkylsilica columns was measured for a mobile-phase pH 3.0. All but 3 of these columns were found to carry a significant positive charge under these conditions. The relative positive charge on these columns was found to correlate approximately with two other column characteristics: relative cation-exchange behavior as measured by the hydrophobic-subtraction model (values of C-2.8), and slow equilibration of the column to changes in the mobile-phase-as evidenced by a slow change in the retention of anionic and cationic solutes with time. The origin of this positive charge may arise from the bonding process, with incorporation of some cationic entity into the stationary phase. 相似文献
134.
We consider a class of mixture models for positive continuous data and the estimation of an underlying parameter θ of the mixing distribution. With a unified approach, we obtain classes of dominating estimators under squared error loss of an unbiased estimator, which include smooth estimators. Applications include estimating noncentrality parameters of chi-square and F-distributions, as well as ρ 2/(1 ? ρ 2), where ρ is amultivariate correlation coefficient in a multivariate normal set-up. Finally, the findings are extended to situations, where there exists a lower bound constraint on θ. 相似文献
135.
Ayotte P Marchand P Daschbach JL Smith RS Kay BD 《The journal of physical chemistry. A》2011,115(23):6002-6014
Molecular beams were used to grow amorphous and crystalline H(2)O films and to dose HCl upon their surface. The adsorption state of HCl on the ice films was probed with infrared spectroscopy. A Zundel continuum is clearly observed for exposures up to the saturation HCl coverage on ice upon which features centered near 2530, 2120, 1760, and 1220 cm(-1) are superimposed. The band centered near 2530 cm(-1) is observed only when the HCl adlayer is in direct contact with amorphous solid water or crystalline ice films at temperatures as low as 20 K. The spectral signature of solid HCl (amorphous or crystalline) was identified only after saturation of the adsorption sites in the first layer or when HCl was deposited onto a rare gas spacer layer between the HCl and ice film. These observations strongly support conclusions from recent electron spectroscopy work that reported ionic dissociation of the first layer HCl adsorbed onto the ice surface is spontaneous. 相似文献
136.
An efficient method to prepare 2,3-diarylimidazo[1,2-a]pyridines is described. The procedure involves a Suzuki cross-coupling reaction followed by a direct arylation at position 3. Imidazo[1,2-a]pyridin-2-yl triflate was identified as a suitable coupling partner, permitting access to a variety of highly functionalized 2,3-diarylimidazo[1,2-a]pyridines. 相似文献
137.
Bis(β-ketoimine) ligands, [R{N(H)C(Me)-CHC(Me)═O}(2)] (L(1)H(2), R = (CH(2))(2); L(2)H(2), R = (CH(2))(3)), linked by ethylene (L(1)) and propylene (L(2)) bridges have been used to form aluminum, gallium, and indium chloride complexes [Al(L(1))Cl] (3), [Ga(L(n))Cl] (4, n = 1; 6, n = 2) and [In(L(n))Cl] (5, n = 1; 7, n = 2). Ligand L(1) has also been used to form a gallium hydride derivative [Ga(L(1))H] (8), but indium analogues could not be made. β-ketoimine ligands, [Me(2)N(CH(2))(3)N(H)C(R')-CHC(R')═O] (L(3)H, R' = Me; L(4)H, R' = Ph), with a donor-functionalized Lewis base have also been synthesized and used to form gallium and indium alkyl complexes, [Ga(L(3))Me(2)] (9) and [In(L(3))Me(2)] (10), which were isolated as oils. The related gallium hydride complexes, [Ga(L(n))H(2)] (11, n = 3; 12, n = 4), were also prepared, but again no indium hydride species could be made. The complexes were characterized mainly by NMR spectroscopy, mass spectrometry, and single crystal X-ray diffraction. The β-ketoiminate gallium hydride compounds (8 and 11) have been used as single-source precursors for the deposition of Ga(2)O(3) by aerosol-assisted (AA)CVD with toluene as the solvent. The quality of the films varied according to the precursor used, with the complex [Ga(L(1))H] (8) giving by far the best quality films. Although the films were amorphous as deposited, they could be annealed at 1000 °C to form crystalline Ga(2)O(3). The films were analyzed by powder XRD, SEM, and EDX. 相似文献
138.
The surface free energy, or surface tension, of a liquid interface gives rise to a pressure jump when the interface is curved. Here we show that a similar capillary pressure arises at the interface of soft solids. We present experimental evidence that immersion of a thin elastomeric wire into a liquid induces a substantial elastic compression due to the solid capillary pressure at the bottom. We quantitatively determine the effective surface tension from the elastic displacement field and find a value comparable to the liquid-vapor surface tension. Most importantly, these results also reveal the way the liquid pulls on the solid close to the contact line: the capillary force is not oriented along the liquid-air interface, nor perpendicularly to the solid surface, as previously hypothesized, but towards the interior of the liquid. 相似文献
139.
S. Marchand I. Bondino A. Ktari E. Santanach-Carreras 《Transport in Porous Media》2017,117(2):169-187
Transparent man-made porous media, also known as micromodels, are a widely used exploration tool in the field of two-phase flow in porous media (Alireza and Sohrabi in Soc Petrol Eng 166435, 2013; Bondino et al., in International symposium of the society of core analysts held in Napa Valley, California, USA, 2013) to enhance the comprehension of oil recovery mechanisms at pore-scale. Although they have more often been used as qualitative visualization tools to explore the elementary physicochemical features of a given flow mechanism, their utilization as a quantitative tool is interesting especially in industrial context, where they represent an easy and low-cost screening tool for complex recovery mechanisms (low salinity waterflooding, polymer flooding, etc). However, the repeatability of these experiments and thus the possibility to derive quantitative conclusions from them appears not to be investigated in the literature in our field of study. In this work, we explore the dispersion of data such as capillary desaturation curves and secondary waterflood recoveries using micromodels of different sizes and different pore patterns from our laboratory and from an external one. Using datasets with low sampling (low number of repeats of an experiment) and with very large sampling, we document the type of data dispersion, we analyze its reasons and we verify to which extent truly quantitative conclusions can be drawn from these datasets. Our study demonstrates that at low sampling drawing quantitative inferences from our datasets is questionable due to the large uncertainty of the produced data. 相似文献
140.
Yvonnick Loidreau Carole Dubouilh‐Benard Pascal Marchand Marie‐Renée Nourrisson Muriel Duflos Catherine Buquet Cécile Corbière Thierry Besson 《Journal of heterocyclic chemistry》2013,50(5):1187-1197
A useful and rapid access to libraries of N‐arylbenzo[b]furo[3,2‐d]pyrimidin‐4‐amines ( 1 ) and their novel benzo[b]thieno[3,2‐d]pyrimidin‐4‐amine analogues ( 2 ) was investigated for the first time. Title compounds were obtained via microwave‐accelerated condensation and Dimroth rearrangement of suitable anilines with N′‐(2‐cyanaryl)‐N,N‐dimethylformimidamides obtained by reaction of benzo[b]furane and benzo[b]thiophene precursors with N,N‐dimethylformamide dimethyl acetal. This work also demonstrates that well‐controlled parameters offer comfortable use of microwave technology and are both safe and beneficial to the environment. Some products obtained in this article exhibit interesting in vitro antiproliferative effects. 相似文献