Simultaneous Spectrophotometric Determination of Imipramine Hydrochloride with Chlordiazepoxide and Nortriptyline Hydrochloride with Fluphenazine Hydrochloride

Spectrophotometry was used with multivariate calibration to simultaneously determine compounds in mixtures. Two antidepressant mixtures were investigated: imipramine hydrochloride and chlordiazepoxide and nortriptyline hydrochloride and fluphenazine hydrochloride. Considerable spectral overlap and large differences in component concentrations were challenges. Since this type of analysis is often performed using complex algorithms, a simple strategy was used here for the simultaneous determination of both mixture components by classical least squares, principal component regression, and partial least squares. Experimental design was used to select the optimum parameters including the wavelength range, sampling interval, software, and derivative order. Accuracy was enhanced by proper wavelength selection. In addition, derivatives of the raw spectra improved the selectivity. The standard deviation, deviation of mean recovery from 100%, and prediction ability of the models were used as the responses. In respect to these terms, first-order derivatization of the spectra and a sampling interval of 1?nm provided the best results. In particular, the low concentration compounds in the mixtures (chlordiazepoxide and fluphenazine) were determined more accurately with precision lower than 3%. The strategy was used for the quality control of pharmaceuticals containing the mixtures without chemical pretreatment.     

Maximizing a Sum Related to Image Segmentation Evaluation

Consider the set S of points in the plane consisting of the ordered pairs (i, j ), where 1 \leqslant i \leqslant m1 \leqslant i \leqslant m and 1 \leqslant j \leqslant n1 \leqslant j \leqslant n. A problem related to the study of segmentation evaluation of visual images concerns finding a permutation σ of the points of S for which the sum

On Traveling Wave Fronts in a Bacterial Growth Model with Density-Dependent Diffusion and Chemotaxis

Bacterial colonies often generate patterns that are characterized by fingerlike projections growing out of the propagating front. In this paper, we analyze the traveling wave fronts in bacterial growth model that accounts for chemotactic movement as well as random motion in density-dependent diffusion. Specifically, the existence of traveling wave solutions to model equations is examined by means of methods of local linear and nonlinear analysis, and numerical simulations. The occurrence is shown of both sharp and smooth traveling wave fronts.     

Numerical study of dynamic thermal conductivity of nanofluid in the forced convective heat transfer

In this work, forced convective heat transfer of nanofluid in the developing laminar flow (entrance region) in a circular tube is considered. The nanofluid thermal conductivity, as an important parameter, is considered as two parts: static and dynamic part. Simulated results show that the dynamic part of nanofluid thermal conductivity due to the Brownian motion has a minor effect on the heat transfer coefficients, on the other hand, static part of thermal conductivity including nanolayer around nanoparticle has an important role in heat transfer.     

Dipeptide Analogues: Synthesis of C-Terminal p-Nitrobenzyl-3-ketoesters of N-Protected Amino Acids

Nitrogen protected amino acid imidazolides undergo facile carbon acylation with magnesium p-nitrobenzylmalonate dihydrate in THF to give pseudodipeptides in 30-79% isolated yield.     

Identities for Sums of a q-Analogue of Polylogarithm Functions

A q-analogue of the polylogarithm function is introduced via a consideration of the spectral zeta-function of the quantum group SU _q (2). We derive certain identities for linear and non-linear combinations of the q-analogue of polylogarithm functions with negative exponents.     

Nonsimilar solutions for free convection from a vertical plate in porous media

A nonsimilar boundary layer analysis has been presented for the free convection along a vertical plate embedded in a fluid-saturated porous medium in the presence of surface mass transfer and internal heat generation. The transformed conservation laws are solved numerically for the cases of variable wall temperature and variable wall heat flux boundary conditions. Results are presented for the details of the velocity and temperature fields as well as Nusselt number. Received on 13 December 1996     

Identification of Single-Particle Configurations at Very High Spin in Some Rare-Earth Nuclei

The nuclear behaviour at high angular momenta is studied by γ-rays emitted in (HI, Xn) reaction. The study of very-high spin states in ¹⁵³Ho via discrete-line γ-ray spectroscopy and a comparison between the partial decay schemes of ¹⁵³Ho and the neighbouring ¹⁵²Dy and ¹⁵⁴Er nuclei are discussed in the context of the high spin structure. Second, we present comments on some phenomena observed at high spin states in ¹⁵³Ho and ¹⁵²Dy nuclei.