N-Protected α-Aminomethylketone Analogues of C-Terminal p-Nitrobenzyl-3-Ketoesters of N-Protected Amino Acids

Hydrogenolysis of N-protected amino acid p-nitrobenzyl-3-ketoesters over palladium on charcoal in THF gave N-protected α-amino methylketones in 45-83% isolated yield.     

Separation of Aliphatic and Aromatic Carboxylic Acids by Conventional and Ultra High-Performance Ion-Exclusion Chromatography

An ion-exclusion chromatography (IELC) comparison between a conventional ion-exchange column and an ultra high-performance liquid chromatography (UHPLC) dynamically surfactant modified C18 column for the separation of an aliphatic carboxylic acid and two aromatic carboxylic acids is presented. Professional software is used to optimize the conventional IELC separation conditions for acetylsalicylic acid and the hydrolysis products: salicylic acid and acetic acid. Four different variables are simultaneously optimized including H₂SO₄ concentration, pH, flow rate, and sample injection volume. Thirty different runs are suggested by the software. The resolutions and the time of each run are calculated and feed back to the software to predict the optimum conditions. Derringer’s desirability functions are used to evaluate the test conditions and those with the highest desirability value are utilized to separate acetylsalicylic acid, salicylic acid, and acetic acid. These conditions include using a 0.35 mM H₂SO₄ (pH 3.93) eluent at a flow rate of 1 mL min⁻¹ and an injection volume of 72 μL. To decrease the run time and improve the performance, a UHPLC C18 column is used after dynamic modification with sodium dodecyl sulfate. Using pure water as a mobile phase, a shorter analysis time and better resolution are achieved. In addition, the elution order is different from the IELC method which indicates the contribution of the reversed-phase mode to the separation mechanism.

     

On Λ2-strong convergence of numerical sequences and Fourier series

We introduce the Λ²-strong convergence of numerical sequences and with it we generalize the concept of Λ-strong convergence of the results published by F. Móricz [2].     

Gastroprotective Effect of Microencapsulated Myrtus communis Essential Oil against Ethanol/HCl-Induced Acute Gastric Lesions

Myrtus communis L. essential oil (EO), mainly composed of myrtenyl acetate (30.6%), linalool (14.9%), α-pinene (11.10%) and 1,8-cineole or eucalyptol (9.9%), was microencapsulated with maltodextrin by emulsification and spray-drying, reaching a yield and efficiency of 43.7 and 48.7%, respectively. The microencapsulated myrtle EO (MMEO) was then evaluated regarding its gastroprotective activity in a model of ethanol/HCl-induced acute gastric ulcer in Wistar rats. Pretreatment with MMEO induced a remarkable inhibition of gastric lesions and acidity, correlated to high healing and protection percentages. Moreover, it exerted a potent anti-inflammatory effect on the gastric mucosa, counteracting EtOH-induced gastric lipoperoxidation and preventing the depletion of the antioxidant enzyme activity of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx). Taken together, the gastroprotective action of encapsulated MMEO may be multi-factorial, and ascribable, at least in parts, to its anti-inflammatory and antioxidant properties.     

Randomized Entangled Mixed States from Phase States

We construct randomized entangled mixed states by using the formalism of phase states for d-dimensional systems (qudits). The randomized entangled mixed states are a special kind of mixed states that exhibit genuine multipartite correlation. Such states are obtained by the application of randomized entangling operators to an arbitrary pair of qudits of a multiqudit system. The study of the entanglement of randomized mixed states is of great importance in quantum computation since any experimental implementation of entangled states in a realistic environment can be made by imperfect entangling gates. We give a brief review of some necessary background about unitary phase operators and phase states of a multi-qudit system. Evolved density matrices arise when qudits of the multi-qudit system interact via a Hamiltonian of Heisenberg type. The randomized entangled states associated with evolved density matrices are derived via the action of an entangling operator on a pair of two qudits {i, j} of the multi-qudit system with some probability p. The randomized entangled mixed states for bipartite, tripartite and multipartite systems are explicitly expressed and their Kraus decomposition properties are discussed.

     

Quantum Group Approach to q-Special Functions

Quantum groups are used to define q-special functions. The Casimir operatorsof a variation of SU _q(2) and E _q(2) are derived. The proposed q-associated Legendreand q-Bessel functions are the eigenfunctions of the Casimirs. The results differfrom ordinary q-special functions, but this is expected since the q-generalizationis not unique.     

Determination of cobalt by catalytic-adsorptive differential pulse voltammetry in the presence of 2-aminocyclopentene-1-dithiocarboxylic acid and nitrite

A novel method for the determination of cobalt(II) by stripping voltammetry is described. It involves an adsorptive accumulation of the cobalt(II)-2-aminocyclopentene-1-dithiocarboxylic acid complex on a hanging mercury drop electrode, followed by a stripping voltammetric measurement of the catalytic reduction current of the complex at –1.4 V at pH = 9 (vs. Ag/AgCl). The effects of various experimental parameters on the catalytic current were investigated. An accumulation time of 60 s results in a low experimental limit of detection of 0.1 ng/mL of Co(II), and 0.50 to 40.0 ng/mL of cobalt can be determined. The relative standard deviation at 0.50 ng/mL is 2.8%. Possible interferences from co-existing ions were also investigated. Received: 17 August 1998 / Revised: 16 November 1998 / Accepted: 20 November 1998     

Star Product and q-Deformation of Grassmann and Symmetric Algebras

We review the relation between the star producton a Poisson-Lie group and the quantum Yang-Baxterequation. We define the q-deformed Grassmann andq-deformed symmetric algebras on a vector space V, and prove that a star product on a triangular(simple quasitriangular) Poisson-Lie group G determinesa q-deformation of both the symmetric and Grassmannalgebras over a dual of a g-module where g is thecorresponding triangular (simple quasitriangular) Liebialgebra of the Poisson-Lie group G.     

Asymptotic properties of markovian master equations

An asymptotic method of analysis of fluctuations in systems far from equilibrium is developed. A systematic singular perturbative expansion of the equation for the generating function is set up, using as smallness parameter the inverse of the size of the system. Static and time-dependent properties are analysed before, near and at a bifurcation point, both for homogeneous and inhomogeneous fluctuations. The connection with critical phenomena near equilibrium is also discussed.