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141.
提出了一种结构模型来分析由工艺引起的波导侧壁起伏对于聚合物波导光学梳状滤波器的滤波特性的影响。含氟聚酰亚胺高分子聚合物制备多级马赫一曾德尔串联型光学梳状滤波器件的工作参量为中心波长1550nm,波长间隔为0.8nm,40通道的波长交错分离。模拟计算:表明,对由高分子聚合物材料制备的多级马赫-曾德尔串联型光学梳状滤波器件,其主要影响是增大了信道之间的串扰,中心波长1550nm处的信道串扰由理想情况下的-40dB降为-12dB,极大地影响了器件的性能。在此基础上,提出一种改善光学梳状滤波器串扰性能的新结构,该结构由多级马赫-曾德尔耦合器和微环共振滤波器串接构成,40个通道的串扰改善为-0dB以下。 相似文献
142.
Tachikawa T Chung HR Masuhara A Kasai H Oikawa H Nakanishi H Fujitsuka M Majima T 《Journal of the American Chemical Society》2006,128(50):15944-15945
The growth dynamics of fluorescent perylene nanocrystals, which are fabricated by the reprecipitation method, was investigated using in situ and ex situ single-particle fluorescence measurements. A red shift in the emission maxima as the aging time increased was observed by single-particle fluorescence spectral measurements. The number and size of the nanocrystals increased with the increasing aging time in water. It was concluded that the metastable intermediates, such as clusters and initial nanoparticles, are relevant for the early stages of nucleation and growth of the perylene nanocrystals. 相似文献
143.
Sakamoto M Tachikawa T Fujitsuka M Majima T 《Langmuir : the ACS journal of surfaces and colloids》2006,22(14):6361-6366
Gold nanoparticles (AuNps) were fabricated in a poly(vinyl alcohol) (PVA) film using the photochemically generated benzophenone ketyl radical and PVA radical by laser irradiation as a reducing agent. The measurements of the surface plasmon band of AuNps indicated that AuNps continued growing in the PVA film for several hours or days after the laser irradiation. The formation process of AuNps in the PVA film was investigated by using laser flash photolysis and UV-vis absorption spectroscopy. Additive doping (formic acid or sodium 2-mercaptoethanesulfonate) in the PVA film dramatically accelerated or inhibited the formation rate of the AuNps, respectively. The doping of formic acid accelerated the formation rate of the AuNps by a factor of 10-20. On the contrary, doping of 2-mercaptoethanesulfonate inhibited the formation of AuNps. The mechanisms of the acceleration and inhibition were investigated by using laser flash photolysis. The effects of additives on the formation process of AuNps are discussed. 相似文献
144.
Samori S Tojo S Fujitsuka M Liang HJ Ho TI Yang JS Majima T 《The Journal of organic chemistry》2006,71(23):8732-8739
Emission from 9-cyano-10-phenylanthracene and 9-cyano-10-phenylethynylanthracenes having donor and acceptor substituents (RA = PA, PEA, OEA, NEA, and DEA) was studied with the time-resolved fluorescence measurement during the pulse radiolysis of RAs in benzene (Bz). PA and DEA showed only monomer emission, while other RAs (PEA, OEA, and NEA) showed both monomer and excimer emissions with much lower intensities. On the basis of the steady-state and transient absorption and emission measurements, the formation of RA in the singlet excited state ((1)RA*) can be attributed to the charge recombination between RA radical cation and anion (RA*+ and RA*-, respectively) which are initially generated from the radiolytic reaction in Bz. It is expected that for PA with a twisted geometry, the charge recombination between PA*+ and PA*- occurs to give (1)PA* during the pulse radiolysis in Bz. For PEA and OEA, pi-stacking interaction is possible for the formation of an encounter complex during the charge recombination between RA*+ and RA*-. For NEA, it is expected that NEA*+ and NEA*- collide neck-to-neck to generate the excimer due to the twisted geometry. For DEA, a considerably twisted structure is assumed to give (1)DEA* with strong ICT character but not (1)(DEA)2* because of the bulky donor substituent. 相似文献
145.
A sensitive high-performance liquid chromatographic method with fluorescence detection to determine 3,4-methylenedioxymethamphethamine (MDMA) and 3,4-methylenedioxyamphethamine (MDA) in human and rat whole blood or plasma samples was developed by using 4-(4,5-diphenyl-1H-imidazol-2-yl)benzoyl chloride (DIB-Cl) as a label. MDMA and MDA in a small amount of blood sample (ca 100 microL) were extracted by liquid-liquid extraction with ethyl acetate, and were derivatized with DIB-Cl under mild conditions (10 min at room temperature). A good separation of DIB-derivatives could be achieved within 45 min using a commercially available ODS column with an isocratic eluent of 10 mM citric acid-20 mM Na(2)HPO(4) aqueous buffer (pH 4.0)-CH(3)CN-CH(3)OH (50:45:5, v/v/v %). The calibration curves prepared with 1-methyl-3-phenylpropylamine (MPPA) as an internal standard showed good linearity (r = 0.999) with 0.36-0.83 ng/mL detection limit at a signal-to-noise ratio of 3. MDMA and MDA in rat whole blood could be monitored for 6 h after a single administration of MDMA (2.2 mg/kg, i.p.). The pharmacokinetic parameters for MDMA and MDA obtained by triplicate measurements were 426 +/- 23 and 39 +/- 6 ng/mL (C(max)), 20 +/- 5 and 100 +/- 10 min (T(max)), respectively. 相似文献
146.
147.
Junichiro Sakamoto Akiko Imaizumi Yoshinori Sasaki Takashi Kamio Mamoru Wakoh Mika Otonari-Yamamoto Tsukasa Sano 《Magnetic resonance imaging》2014
Purpose
To evaluate the use of the intravoxel incoherent motion (IVIM) technique in half-Fourier single-shot turbo spin-echo (HASTE) diffusion-weighted imaging (DWI), and to compare its accuracy to that of apparent diffusion coefficient (ADC) to predict malignancy in head and neck tumors.Patients and methods
HASTE DW images of 33 patients with head and neck tumors (10 benign and 23 malignant) were evaluated. Using the IVIM technique, parameters (D, true diffusion coefficient; f, perfusion fraction; D*, pseudodiffusion coefficient) were calculated for each tumor. ADC values were measured over a range of b values from 0 to 1000 s/mm2. IVIM parameters and ADC values in benign and malignant tumors were compared using Student's t test, receiver operating characteristics (ROC) analysis, and multivariate logistic regression modeling.Results
Mean ADC and D values of malignant tumors were significantly lower than those of benign tumors (P < 0.05). Mean D* values of malignant tumors were significantly higher than those of benign tumors (P < 0.05). There was no significant difference in mean f values between malignant and benign tumors (P > 0.05). The technique of combining D and D* was the best for predicting malignancy; accuracy for this model was higher than that for ADC.Conclusions
The IVIM technique may be applied in HASTE DWI as a diagnostic tool to predict malignancy in head and neck masses. The use of D and D* in combination increases the diagnostic accuracy in comparison with ADC. 相似文献148.
Despite significant advances in the catalytic direct arylation of heteroarenes, the application of this reaction to pyridines has been met with limited success. An oxidative nucleophilic arylation strategy has been developed to overcome this problem. Pyridine, pyrazine, quinolone, and related electron‐deficient N‐heteroarenes can be arylated at the most electrophilic site using the developed nickel‐catalyzed reaction. This protocol serves as a complementary method to catalytic direct arylation reactions. 相似文献
149.
Tachikawa T Cui SC Fujitsuka M Majima T 《Physical chemistry chemical physics : PCCP》2012,14(12):4244-4249
Graphene oxide (GO) nanosheets have received a great deal of attention for a wide range of applications from optoelectronic devices to biological sensors. We now report a mechanistic study of the interfacial electron transfer (ET) processes between organic dye molecule, 9-phenyl-2,3,7-trihydroxy-6-fluorone (PF), and nanometre-sized GO sheets using ensemble-averaged and single-molecule spectroscopies. The ET dynamics was characterized by the direct observation of the PF radical cation during the laser flash photolysis, and its reaction rate was determined to be ~10(11) s(-1). The single-molecule fluorescence spectroscopy was utilized to clarify the heterogeneous nature of the interfacial ET within individual composites. Their fluorescence lifetimes and spectra were found to vary from composite to composite, possibly due to the different local structures and molecular interactions. The autocorrelation analysis of fluorescence intensity trajectories also revealed the temporal fluctuation of the ET reactivity. 相似文献
150.
Hongoh M Haratake M Fuchigami T Nakayama M 《Dalton transactions (Cambridge, England : 2003)》2012,41(24):7340-7349
In this paper, we describe a thiol-mediated and energy-dependent membrane transport of selenium by erythroid anion exchanger 1 (AE1, also known as band 3 protein). The AE1 is the most abundant integral protein of red cell membranes and plays a critical role in the carbon dioxide transport system in which carbon dioxide is carried as bicarbonate in the plasma. This protein mediates the membrane transport of selenium, an essential antioxidant micronutrient, from red cells to the plasma in a manner that is distinct from the already known anion exchange mechanism. In this pathway, selenium bound to the cysteine 93 of the hemoglobin β chain (Hb-Cysβ93) is transported by the relay mechanism to the Cys317 of the amino-terminal cytoplasmic domain of the AE1 on the basis of the intrinsic interaction between the two proteins and is subsequently exported to the plasma via the Cys843 of the membrane-spanning domain. The selenium export did not occur in plain isotonic buffer solutions and required thiols, such as albumin, in the outer medium. Such a membrane transport mechanism would also participate in the export pathways of the nitric oxide vasodilator activity and other thiol-reactive substances bound to the Hb-Cysβ93 from red cells to the plasma and/or peripherals. 相似文献