Synthesis,characterization and biological studies of cobalt(II) and nickel(II) complexes with new Schiff bases

Complexes of CoII and NiII with new Schiff bases derived from 4-amino-5-sulfanyl-1,2,4-triazoles and glyoxal, biacetyl or benzil have been prepared. All have the stoichiometry ML(H2O)2, with L coordination via the two imine nitrogens and two thiolato sulfurs in an overall octahedral geometry.Some of the complexes were screened for their antibacterial and antifungal activity, and one representative CoII complex was evaluated for oxytocic activity.     

Phosphomolybdic acid promoted Kabachnik–Fields reaction: an efficient one-pot synthesis of α-aminophosphonates from 2-cyclopropylpyrimidine-4-carbaldehyde

2-Cyclopropylpyrimidin-4-yl-aryl/benzothiazole derived α-aminophosphonates were synthesized in a simple and efficient method from a three-component condensation reaction of 2-cyclopropylpyrimidin-4-carbaldehyde, various anilines/benzothiazole amines, and different phosphites by using 0.5 mol % of phosphomolybdic acid (PMA, H₃PMo₁₂O₄₀) in dichloromethane at room temperature in good to excellent yields with short reaction times.