A Novel Method for the Improved Skin Whitening Effect Based on Nanostructured Lipid Carrier

The effect of humidity on the holographic grating diffraction efficiency and transmittance kinetics in the E204Q BR gelatin film is investigated. We found a correlation between the accumulation of the red-light absorbing O intermediate in the later part of the E204Q BR photocycle and sharpness (decay to the steady-state) of the holographic recording kinetics. As shown, at humidity exceeding 95% the ratio between the peak and steady-state of the diffraction efficiency for the weak probe beam (670 nm) can reach 8.7 in the E204Q BR film, which is sufficient for realization of an efficient novelty filter.     

Metal complexes as potential modulators of inflammatory and autoimmune responses

Over the past few decades, the realm of inorganic medicinal chemistry has been dominated by the study of the anti-cancer properties of transition metal complexes, particularly those based on platinum or ruthenium. However, comparatively less attention has been focused on the development of metal complexes for the treatment of inflammatory or autoimmune diseases. Metal complexes possess a number of advantages that render them as attractive alternatives to organic small molecules for the development of therapeutic agents. In this perspective, we highlight recent examples in the development of transition metal complexes as modulators of inflammatory and autoimmune responses. The studies presented here serve to highlight the potential of transition metal complexes in modulating inflammatory or immune pathways in cells.     

功能化离子液体液化木粉及其酚醛复合材料

合成了氯代1-(2-羟乙基)-3-甲基咪唑离子液体[He MIM]Cl、溴代1-乙胺基-3-甲基咪唑离子液体[Ae MIM]Br和氯代1-羧乙基-3-甲基咪唑离子液体[Ce MIM]Cl 3种功能化咪唑离子液体,并分别进行了红外与氢核磁结构表征.然后用3种离子液体液化木粉,液化3 h后向体系直接加入苯酚、甲醛和氢氧化钠,制备酚醛复合材料,并采用FTIR、XRD、DSC和SEM对酚醛复合材料进行结构、性能与形貌测试,研究离子液体种类对木粉液化率及酚醛树脂性能的影响.结果表明,离子液体及其液化木粉产物制备的酚醛复合材料性能得到明显改善.[Ce MIM]Cl液化效果最好,90℃液化率高达24.6%,当[Ce MIM]Cl与木粉质量比为10∶1时,制备的酚醛复合材料的游离醛释放量由原来的3.64%降低到0.92%.离子液体[Ae MIM]Br能将酚醛复合材料的冲击强度由原来的0.93 k J/m2提高到6.96 k J/m2,而[Ae MIM]Br及其液化的木粉产物制备的酚醛复合材料拉伸强度从原来的3.28 MPa提高到9.70 MPa.     

Pore-Scale Level Set Simulations of Capillary-Controlled Displacement with Adaptive Mesh Refinement

Transport in Porous Media - Multiphase flow simulations on imaged porous rock structures require numerical methods that are accurate and robust when applied on complex geometries. A key element in...     

Temperature and pH dual‐sensitive polyaspartamide derivatives for antitumor drug delivery

The pH‐sensitive tertiary amino groups were introduced to synthesize temperature and pH dual‐sensitive degradable polyaspartamide derivatives (phe/DEAE‐g‐PHPA) containing pendant aromatic structures and ionizable tertiary amino groups. The thermo/pH‐responsive behavior of phe/DEAE‐g‐PHPA polymer can be tuned by adjusting the graft copolymer composition. Due to the pH sensitivity of the phe/DEAE‐g‐PHPA‐g‐mPEG polymer with hydrophilic long PEG chain, the micelles and the anticancer drug‐loaded micelles were prepared by a quick pH‐changing method without using toxic organic solvent. The obtained polymeric micelles, paclitaxel‐loaded micelles and doxorubicin‐loaded micelles were stable under physiological conditions. Both the drug‐loaded micelles showed much faster release at pH 5 than at pH 7.4. The doxorubicin‐loaded micelles showed obvious and better anticancer activity against both HepG2 and HeLa cells than free doxorubicin. Thus these nontoxic, dual thermo‐ and pH‐sensitive phe/DEAE‐g‐PHPA‐g‐mPEG micelles may be a promising anticancer drug delivery system. © 2015 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2016 , 54, 879–888     

Adaptive integral sliding mode control with payload sway reduction for 4-DOF tower crane systems

Nonlinear Dynamics - An adaptive integral sliding mode control (AISMC) method with payload sway reduction is presented for 4-DOF tower cranes in this paper. The designed controller consists of...     

Calorimetry in testing waste materials from the brown coal combustion

The calorimetric measurements were applied in testing the wastes collected from different furnaces in electric power plants as materials to be used in civil engineering. The fly ash materials were collected from two power stations based on different brown coal deposits and working with conventional and fluidized bed installation. The reactivity of high calcium fly ash from sub-bituminous coal combustion has been proved in calorimetric, conductometric, chemical shrinkage, and rheological measurements before their practical implementation on larger scale. Highly soluble components of fly ash contribute to the hydration products and structure formation, followed by setting and hardening of fly ash–cement mixture. These results have been the base of research project aimed in the innovative solutions dealing with the management of deposits of wastes generated as a result of coal combustion. The standardization and potential use on larger scale of these materials, necessary from the environmental point of view, seems to be the question of nearest future.