手性二胺修饰的Ru-TPP/γ-Al2O3催化苄叉丙酮不对称加氢反应

在温和条件下制备了三苯基膦(TPP)作保护剂的负载钌催化剂Ru-TPP/γ-Al2O3,以(1S,2S)-1,2-二苯基乙二胺,(S)-1,1-二(对甲氧苯基)-2-异丙基乙二胺,(8S,9S)-9-氨基(9-脱氧)二氢辛可尼定和(1S,2S)-环己二胺为手性修饰剂,考察了Ru-TPP/γ-Al2O3在苄叉丙酮不对称加氢反应中的催化性能.结果表明,以(1S,2S)-1,2-二苯基乙二胺作为修饰剂时,催化剂具有较高的活性和选择性.在有K2CO3存在的异丙醇和水的混合溶液中,在氢气压力4MPa,40℃和8h的条件下,苄叉丙酮的转化率达到了99%,对羰基加氢的选择性大于98%,不饱和醇的光学纯度ee值为47%.     

MOLECULAR STRUCTURES AND SINGLE CRYSTAL ESR SPECTRA OF IMIDAZO-LATE-BRIDGED Co(Ⅲ)-Cu(Ⅱ)-Co(Ⅲ)AND Co(Ⅲ)-Zn(Ⅲ)-Co(Ⅲ) COMPLEXES

The structures of the heterotrinuclear complexes, [(NH_3)_5ColmCu(dien)ImCo(NH_3)_5]-(C10_4)_6·4H_20 and [(NH_3)_5CoImZn(dien)ImCo(NH_3)_5]-(ClO_4)_6·4H_2O, are reported. Co--Cu--Cocrystallizes in the monoclinic space group C2/c with a =32.414(4), b= 9.421(1), c=15.167(5)?,β= 90.91(2)°, Z=4 and Co--Zn--Co in the same space group with a = 32.578(2), b = 9.419(1), c = 15.125(3)?, β=91.10(1)°Z=4. The Cu(Ⅱ) and Zn(Ⅱ) geometriesare intermediate between a trigonal bipyramid and a square pyramid,the Co(Ⅲ) is a-hexagonal coordination and the dien ligand shows a disordered contribution in the respectivestructure.The magnetic properties of Co--Cu--Co are investigated. From the single crystalESR spectra studies, the anisotropic g and A tensors and electronic spin-density of Co--Cu--Co are obtained and the nature of the bonding for Cu~(2+) is discussed.     

HTS块材与磁场间相互作用估算方法研究

HTS块材电磁机构日趋复杂，为了实现系统结构和电磁设计的优化需要建立一种简单可靠的方法来估算系统内部的相互作用．描述HTS磁学特性通常采用热激活磁通跳跃、磁通流动等系列模型，用其描述相互作用各有优缺点．为此，我们实验测试了HTS块材与永磁间相互作用随空间相对位置变化．并基于HTS完全抗磁性和临界态模型构造的B（H）曲线进行模拟仿真，通过与实验结果的比较．力求寻找一种方便可行、较为准确及可靠的HTS块材与磁场间相互作用估算方法．     

一种具有光致变色特性的膜蛋白/聚合物复合膜

通过基因工程技术将古紫质4(archaerhodopsin-4,AR4)膜蛋白的基因转入本身不表达该蛋白质、也不表达玉红素的嗜盐菌株L33中,去除了天然菌株xz515所获得的AR4膜蛋白脂环境中的玉红素,优化了AR4的光致变色性能.将重组古紫质4包埋于聚乙烯醇中制成复合膜,并通过提高体系的pH值,延长了M态的寿命,进一步实现了简单图案记录,验证了该活性蛋白质与聚合物的复合材料具有光信息存储功能.     

池蝶蚌(Hyriopsis schlegeli)血淋巴的抗菌力、溶菌酶和酚氧化酶活力

通过分光光度法对池蝶蚌的抗菌力,溶菌酶和酚氧化酶活性进行了分析.结果表明,经嗜水气单胞菌感染后,池蝶蚌对这两种细菌的抗菌力分别为0.61±0.01 U和0.14±0.02U;所有实验组对大肠杆菌和金黄色葡萄球菌均无抑制效果.随着年龄的增长,溶菌酶活性也显著增加,第4龄蚌的溶菌酶活力可达0.93±0.05U,比1龄蚌的酶活力高一倍左右;十二烷基磺酸钠(SDS)能够激活酚氧化酶(PO)酶原系统,2龄前,酚氧化酶活力逐渐增强,3龄和4龄逐渐减弱,2龄蚌的PO活性最高,为22.70±4.39 U.研究表明,池蝶蚌血淋巴中免疫因子的种类和表达活性在个体不同发育阶段中呈现出差异,推测可能与水体环境对蚌的作用有关.     

Novel Photochromic Compounds Responding to InGaN Diode Laser;Synthesis and Photochromic Behavior of Dibenzothiophenylcycloalkenes

lnrecentyears,phot0chromicc0mpoundshaveattractedincreasingattentionduetotheirpotentialapplicati0ninopticaldatast0rage'.Amongthem,1,2-diarylethenesc0nstituteanimp0rtantclassowingtotheirbistationarystatesthermalstabilityandfatigueresistance2.Mucheffortshavebeens0farpaidtosynthesizethematerialsthatabsorbnear-infraredlightinordertoachievecompatibilitywithconventi0nalinfrareddiodelaser(Xse0.8um)usedincompactdiscsystem.Mostoftheclosedf0rms0ftherep0rtedsynthesizeddiaryletheneshavetheirabsorPtionmaxim…     

在RABiTS基带上制备Tl-2212超导薄膜

我们研究了Tl-2212超导薄膜在带有YSZ／CeO2缓冲层和带有CeO2／YSZ／CeO2缓冲层的Ni金属RABiTS基带上的生长情况．基带上的缓冲层是采用PLD方法制备的，Tl-2212薄膜的制备采用了磁控溅射和后热处理两步方法．XRD实验结果表明，Tl-2212薄膜都具有很好的c轴垂直于膜面的织构，并具有双向外延生长特性．在CeO2／YSZ／CeO2／Ni基带上制作的Tl-2212薄膜的Tc达到102．8K，Jc（77K，0T）达到2．6MA／cm^2；在YSZ／CeO2／Ni基带上薄膜的Tc可达97．7K，Jc（77K，0T）也可以达到0．45MA／cm^2．     

28.7MeV/u的 14，16，18 O+7，9Be反应中的同位素分布研究

用同位旋相关的Boltzmann-Langevin方程研究了在入射能量为28.7MeV/u下,不同弹核^14O,^16O和^18O轰击不同靶核^7Be和^9Be的反应,计算了生成碎片的产生截面,发现用丰中子（缺中子）炮弹或丰中子（缺中子）靶进行反应,所得到的产物均有丰中子（缺中子）的碎片出现。同位素分布宽度和峰位与入射体系密切相关,产生碎片的电荷数越接近入射弹核的电荷数,则同位素分布的宽度越大,峰位偏离β稳定线值越远,其同位旋效应越明显。。     

Rh2CO2/Al2O3上H2吸附及CO和H2共吸附

CO加氢反应机理一直是许多化学工作者感兴趣的课题．Rh催化剂因其优良的性能而被用于 CO加氢机理研     

和厚朴酚对非小细胞肺癌细胞的辐射增敏效应

研究了和厚朴酚（HNK）对非小细胞肺癌（NSCLC）细胞系A549和H1299对低线性能量转移（LET） X射线和高LET碳离子的辐射增敏效应。首先用CCK-8检测了HNK对A549和H1299细胞的生长抑制情况,发现20 μmol/L的HNK处理对细胞的生长抑制作用较弱。用该浓度HNK预处理细胞2 h后给予不同剂量X射线或碳离子的照射,克隆存活法检测细胞的辐射敏感性,Annexin-PI双染法检测细胞凋亡,γH2AX焦点法检测DNA的双链断裂（DSB）损伤。实验结果显示:与X射线相比,NSCLC细胞对碳离子更敏感,HNK预处理仅对碳离子照射有辐射增敏作用;与碳离子单独照射相比,HNK预处理联合碳离子照射诱导了更明显的细胞凋亡;在照射后24 h,HNK预处理联合碳离子照射引起的细胞γH2AX焦点阳性率维持在较高水平,而X射线照射没有这些效应。实验结果表明,HNK预处理抑制了NSCLC细胞DNA的DSB修复,诱导了细胞凋亡的发生,从而提高了细胞对碳离子的辐射敏感性。The radiosensitizing effect of Honokiol (HNK) on non-small cell lung carcinoma (NSCLC) cell lines A549 and H1299 to low-linear energy transfer (LET) X-rays and high-LET carbon ions was investigated in this study. First, the inhibitory effects of HNK on the growth of A549 and H1299 cells were detected by CCK-8 assay, and 20 μmol/L HNK treatment was found to induce a growth inhibitory effect slightly in these two cell lines. Cells were pre-treated with HNK and then irradiated with X-rays and carbon ions of different doses. Cellular radiosensitivity, apoptosis and DNA damage were analyzed by clonogenic survival, Annexin-PI staining and γH2AX foci, respectively. The results showed the cells were more sensitive to carbon ion irradiation compared to X-rays and the radiosensitization of HNK was only observed after carbon ion irradiation. Furthermore, the co-treatment led to higher apoptosis rate 48 h after irradiation and increased the positive rate of γH2AX foci 24 h after irradiation in A549 and H1299 cells compared with those in the groups treated with carbon ion irradiation alone. These phenomena were not observed after X-ray irradiation. Our data suggest that the pre-treatment with HNK inhibited DNA DSB repair, induced apoptosis and then enhanced the cellular radiosensitivity to carbon ions in NSCLC cells.