高效液相色谱法测定普卢利沙星胶囊的含量

建立高效液相色谱法测定普卢利沙星胶囊含量的方法。采用高效液相色谱法,以0.01mol.L-1盐酸溶液为溶剂,测定波长为280nm。在10—100μg.mL-1浓度范围内,主峰面积与相应的浓度呈良好的线性关系（r=0.9998）。重复测定峰面积平均值为1215.9（n=6）,相对标准偏差为0.7%。平均回收率为99.77%（n=9）,相对标准偏差为0.26%。该方法准确简便、重复性好,可作为普卢利沙星胶囊含量测定的有效方法。     

Design,Implementation, Simulation,and Visualization of a Highly Efficient RIM Microfluidic Mixer for Rapid Freeze-Quench of Biological Samples

Abstract  

Rapid freeze-quench (RFQ) trapping of short-lived reaction intermediates for spectroscopic study plays an important role in the characterization of biological reactions. Recently, there has been considerable effort to achieve sub-millisecond reaction deadtimes. We present here a new, robust, high-velocity microfluidic mixer that enables such rapid freeze-quenching. It is a based on the mixing method of two impinging jets commonly used in reaction injection molding of plastics. This method achieves efficient mixing by inducing chaotic flow at relatively low Reynolds numbers (Re = 140). We present the first mathematical simulation and microscopic visualization of mixing in such RFQ micromixers, the results of which show that the impinging solutions efficiently mix within the mixing chamber. These tests, along with a practical demonstration in an RFQ setup that involves copper wheels, show that this new mixer can in practice provide reaction deadtimes as low as 100 μs.     

与资本市场收益变动相关的最优再保险策略

本文在假定资本市场变动与保险公司资本收益变动存在相关性的情况下,研究了保险公司最优再保险策略问题.利用HJB-变分不等方程,获得了最优再保险策略和最小破产概率的显示表达式,推广了文献[3]的结果.     

具有多重非线性的非牛顿多方渗流方程的整体存在性与非存在性

考虑了一个具有多重非线性的抛物模型中,非线性扩散项、非线性反应项和非线性边界流三种非线性机制之间的相互作用.通过构造自相似上解和自相似下解,获得了临界整体存在性曲线和临界Fujita曲线.     

微分方程解的存在区间的确定

从六个方面说明了确定一阶微分方程解的存在区间的方法.     

(R)-乙基-2-吡啶亚砜与(4R,5R)-TADDOL包结晶体 [C7H9NOS·C31H30O4]的晶体结构分析

（Ｒ）－乙基－２－吡啶亚砜与（４Ｒ，５Ｒ）－二（羟基－二苯基－甲基）－２，２－二甲基－１，３－二氧戊环（ＴＡＤ－ＤＯＬ）可以形成物质的量比为１∶１的手性包结晶体，Ｘ射线衍射分析确定该晶体属单钭晶系，Ｐ２１空间群，ａ＝０．９７０１（２）ｎｍ，ｂ＝０．９９５３（２）ｎｍ，ｃ＝１．７３９２（２）ｎｍ；β＝９２．０７９°（１４），Ｖ＝１．６７８１（５）ｎｍ３，Ｚ＝２，Ｄｃ＝１．２３０ｇ／ｃｍ３，分子式Ｃ３８Ｈ３９ＮＯ５Ｓ，Ｍｒ＝６２１．７６，最终偏离因子Ｒ＝０．０３５１，ＲＷ２＝０．０７７２，Ｆｌａｃｋ值为０．１（２）．结构分析表明，主客体存在分子间氢键．光学纯的ＴＡＤＤＯＬ与消旋的乙基吡啶亚砜（１）作用时，ＴＡＤＤＯＬ对１具有很好的手性识别能力，选择性地与１的一个对映体形成氢键，长成晶体．参照晶体结构确定了１的两个对映体的绝对构型     

Generalized Algorithm for Restricted Weak Composition Generation

This paper presents a new algorithm that arrives at a generalized solution for the generation of restricted weak compositions of n-parts. In particular, this generalized algorithm covers many commonly sought compositions such as bounded compositions, restricted compositions, weak compositions, and restricted part compositions. Introduced is an algorithm for generating generalized types of restricted weak compositions called first-order, and second-order restricted weak compositions.     

非水溶液滴定法测定普卢利沙星的含量

以0.1mol.L-1高氯酸为滴定液,结晶紫为指示剂,用非水滴定法测定普卢利沙星。重复测定普卢利沙星含量平均值为99.4%(n=6),相对标准偏差为0.1%。该方法准确简便、重复性好,可作为普卢利沙星含量测定的有效方法。     

Dominant strategy mechanisms for contract auctions with risk aversion and moral hazard

Within the class dominant strategy incentive compatible mechanisms, we show that there exists an optimal contracting mechanism for the principal for a version of the incomplete information principal-agent problem in which several agents compete for a contract and the principal selects an agent via a contract auction. In our auction model, we assume that the principal and the agents are risk averse, and we allow for uncountably many agent types. We also assume that the principal's probability measure over type profiles in such that correlation between agent's types is possible. Thus, we do not require that agents' types be independently distributed. Finally, we impose limited liability constraints upon the set of contracts. Due to the nature of the individual rationality and incentive compatibility constraints, the existence problem is nonstandard and novel existence arguments are required. We prove existence using a measurable selection result and a new notion of compactness called K-compactness.