Efficient Synthesis of New Fused Thiadiazines and Their Spectroscopic,In Silico Drug Likeness,and ADME Properties

Russian Journal of Organic Chemistry - A series of novel fused thiadiazine derivatives have been simply synthesized through the reaction of hydrazinecarbodithioic acid with various cyclic...     

Thermal analysis techniques applied to study corrosion mechanisms of SEN used in the steel continuous casting process

Journal of Thermal Analysis and Calorimetry - Recent advances in the technology of black refractories for steel continuous casting promote the development of materials that operate at extreme...     

Synthesis and properties of novel 4-(diarylmethyl)pyridines based on pyridoxal 5′-phosphate

Russian Chemical Bulletin - The reaction pyridoxal 5′-phosphate with resorcinols in EtOH in the presence of concentrated HCl gives hydrochlorides of the corresponding...     

Magnetically separable biocatalysts based on glucose oxidase for d-glucose oxidation

Russian Chemical Bulletin - Biocatalytic systems based on glucose oxidase immobilized on the surface of magnetically separable oxides SiO2 and Al2O3 were studied. Silicon and aluminum oxides...     

Cathodic Reduction of Zinc Oxide in Alkaline Electrolyte

Russian Journal of Electrochemistry - The reduction of zinc oxide in a limited volume of the alkaline electrolyte is studied. Methods of chronopotentiometry, chronoamperometry, and...     

Biradical with a polyfluorinated terphenylene backbone

Russian Chemical Bulletin - A method was developed for the synthesis of perfluoro-1,1′:4′,1″-terphenyl by the reaction of chloroperfluorobenzene with zinc dust followed by the...     

Synthesis and study of interconversions of new indoline spiropyrans based on 4-hydroxy-3,5-diformylbenzoic acid

The synthesis of new indoline spiropyran by the cyclocondensation in methanol revealed that the free aldehyde group of the target spiropyran is easily converted into the dimethyl acetal moiety without the addition of an acid catalyst, giving 8′-dimethoxymethyl-1,3,3-trimethylspiro[indoline-2,2′-2H-chromene]-5,6′-dicarboxylic acid as a single reaction product. The structure of this compound was confirmed by NMR spectroscopy and mass spectrometry. The molecular structure was also established by single-crystal X-ray diffraction. The Hirshfeld surfaces were generated and analyzed and intermolecular interactions in the crystal were investigated using the CrystalExplorer software package. The reverse hydrolysis reaction of dimethyl acetal to the aldehyde group proceeds under mild conditions in dimethyl sulfoxide, as shown by NMR spectroscopy.

     

Synthesis,Structure, and Biological Activity of N-p-(Dimethylamino)-N′-(p-dimethylaminobenzylidene)-N,N′′-diphenylbenzohydrazonohydrazide

Russian Journal of General Chemistry - A three-component reaction of 3,5-diacetyl-2,6-dimethylpyridine, p-N-dimethylaminobenzaldehyde and phenylhydrazine in the presence of KOH in ethanol gave the...     

Synthesis and Antitumor Activity of 5-Phenyl-1,3-thiazole-4-sulfonamide Derivatives

Russian Journal of General Chemistry - A method for the synthesis of 5-phenyl-1,3-thiazole-4-sulfonyl chloride was developed based on the cyclization of ethyl...     

Synthesis and Molecular Structure of 3-[N-Acetyl(3,5-dimethylphenyl)amino]-5,7-di(tert-butyl)-2-{5,8-dimethyl-4-[(3,5-dimethylphenyl)amino]quinolin-2-yl}tropone

Russian Journal of General Chemistry - Acylation of 5,7-di(tert-butyl)-2-{5,8-dimethyl-4-[(3,5-dimethylphenyl)amino]quinolin-2-yl}-3-[(3,5-dimethylphenyl)amino]tropone leads to...