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31.
DK Basa  S Raj  HC Padhi  M Polasik  F Pawlowski 《Pramana》2002,58(5-6):783-786
K β-to-K α X-ray intensity ratios of Fe and Ni in pure metals and in Fe x Ni1−x alloys (x=0.20, 0.50, 0.58) exhibiting similar crystalline structure have been measured following excitation by 59.54 keV γ-rays from a 241Am point source, to understand as to why the properties of permalloy Fe0.2Ni0.8 is distinct from other alloy compositions. It is observed that the valence electronic structure of Fe0.2Ni0.8 alloy is totally different from other alloys which may be attributed to its special magnetic properties.  相似文献   
32.
We present an extensive study of the unique thermal and mechanical dynamics for narrow-line cooling on the 1S0-3P1 88Sr transition. For negative detuning, trap dynamics reveal a transition from the semiclassical regime to the photon-recoil-dominated quantum regime, yielding an absolute minima in the equilibrium temperature below the single-photon-recoil limit. For positive detuning, the cloud divides into discrete momentum packets whose alignment mimics lattice points on a face-centered-cubic crystal. This novel behavior arises from velocity selection and "positive feedback" acceleration due to a finite number of photon recoils. Cooling is also achieved with blue-detuned light around a velocity where gravity balances the radiative force.  相似文献   
33.
Presently, the Stark effect contributes the largest source of uncertainty in a ytterbium optical atomic clock through blackbody radiation. By employing an ultracold, trapped atomic ensemble and high stability optical clock, we characterize the quadratic Stark effect with unprecedented precision. We report the ytterbium optical clock's sensitivity to electric fields (such as blackbody radiation) as the differential static polarizability of the ground and excited clock levels α(clock) = 36.2612(7) kHz?(kV/cm)(-2). The clock's uncertainty due to room temperature blackbody radiation is reduced by an order of magnitude to 3×10(-17).  相似文献   
34.
We have extended Ramsey spectroscopy by stepping the probe frequency during the two Ramsey excitation pulses to compensate frequency shifts induced by the excitation itself. This makes precision Ramsey spectroscopy applicable even for transitions that have Stark and Zeeman shifts comparable to the spectroscopic resolution. The method enables a new way to evaluate and compensate key frequency shifts, which benefits in particular, optical clocks based on magnetic field-induced, spectroscopy, two-photon transitions, or heavily forbidden transitions.  相似文献   
35.
We propose a combination of electromagnetically induced transparency-Raman and pulsed spectroscopy techniques to accurately cancel frequency shifts arising from electromagnetically induced transparency fields in forbidden optical clock transitions of alkaline earth atoms. At appropriate detunings, time-separated laser pulses are designed to trap atoms in coherent superpositions while eliminating off-resonance ac Stark contributions, achieving efficient population transfer up to 60% with inaccuracy <10(-17). Results from the wave-function formalism are confirmed by the density matrix approach.  相似文献   
36.
The equations of magnetostatic equilibria for a plasma in agravitational field are investigated analytically. For equilibriawith an ignorable spatial coordinate, the equations reduce toa single nonlinear elliptic equation for the magnetic potentialu known as the Grad-Shafranov equation. By specifying the arbitraryfunctions in this equation, a Liouville equation is obtained.Bäcklund transformations are described and applied to obtainexact solutions for the Liouville equation modelling an isothermalmagnetostatic atmosphere, in which the current density J isproportional to the exponential of the magnetic potential andmoveover falls off exponentially with distance vertical to thebase with an e-folding distance equal to the gravitational scaleheight.  相似文献   
37.
    
The unsteady compressible Reynolds‐averaged Navier–Stokes equations are discretized using the Osher approximate Riemann solver with fully implicit time stepping. The resulting non‐linear system at each time step is solved iteratively using a Newton/GMRES method. In the solution process, the Jacobian matrix–vector products are replaced by directional derivatives so that the evaluation and storage of the Jacobian matrix is removed from the procedure. An effective matrix‐free preconditioner is proposed to fully avoid matrix storage. Convergence rates, computational costs and computer memory requirements of the present method are compared with those of a matrix Newton/GMRES method, a four stage Runge–Kutta explicit method, and an approximate factorization sub‐iteration method. Effects of convergence tolerances for the GMRES linear solver on the convergence and the efficiency of the Newton iteration for the non‐linear system at each time step are analysed for both matrix‐free and matrix methods. Differences in the performance of the matrix‐free method for laminar and turbulent flows are highlighted and analysed. Unsteady turbulent Navier–Stokes solutions of pitching and combined translation–pitching aerofoil oscillations are presented for unsteady shock‐induced separation problems associated with the rotor blade flows of forward flying helicopters. Copyright © 2000 John Wiley & Sons, Ltd.  相似文献   
38.
Many of the processes occurring in nature involve membrane transport. Some of the functions performed by such membranes appear to be unique, as well as efficient, and it would be possible to make synthetic membranes having similar properties. This paper discusses some of these phenomena. Further, it may be quite possible that knowledge of synthetic membranes can be extended to better understand the changes which occur in biological ones, and this is also mentioned here.  相似文献   
39.
    
We have analysed 131 fragment-to-lead (F2L) examples targeting a wide variety of protein families published by academic and industrial laboratories between 2015–2019. Our assessment of X-ray structural data identifies the most common polar functional groups involved in fragment-protein binding are: N–H (hydrogen bond donors on aromatic and aliphatic N–H, amides and anilines; totalling 35%), aromatic nitrogen atoms (hydrogen bond acceptors; totalling 23%), and carbonyl oxygen group atoms (hydrogen bond acceptors on amides, ureas and ketones; totalling 22%). Furthermore, the elaboration of each fragment into its corresponding lead is analysed to identify the nominal synthetic growth vectors. In ∼80% of cases, growth originates from an aromatic or aliphatic carbon on the fragment and more than 50% of the total bonds formed are carbon–carbon bonds. This analysis reveals that growth from carbocentric vectors is key and therefore robust C–H functionalisation methods that tolerate the innate polar functionality on fragments could transform fragment-based drug discovery (FBDD). As a further resource to the community, we have provided the full data of our analysis as well as an online overlay page of the X-ray structures of the fragment hit and leads: https://astx.com/interactive/F2L-2021/

An in depth meta analysis of 131 fragment-to-lead case-studies has shown the importance of synthetic methods that allow carbon-centred synthetic elaboration in the presence of polar pharmacophores.  相似文献   
40.
The phase coherence of an ultrastable optical frequency reference is fully maintained over actively stabilized fiber networks of lengths exceeding 30 km. For a 7-km link installed in an urban environment, the transfer instability is 6 x 10{-18} at 1 s. The excess phase noise of 0.15 rad, integrated from 8 mHz to 25 MHz, yields a total timing jitter of 0.085 fs. A 32-km link achieves similar performance. Using frequency combs at each end of the coherent-transfer fiber link, a heterodyne beat between two independent ultrastable lasers, separated by 3.5 km and 163 THz, achieves a 1-Hz linewidth.  相似文献   
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