An efficient synthesis of novel deoxy phospha sugar pyrimidine nucleosides

An efficient method is described in the synthesis of several novel deoxy phospha sugar pyrimidine nucleosides in racemic form, analogs of normal sugar nucleosides, in high yields by treatment of (±)-2-aminophospholane 1-oxide with several, α-cyano-, -acetyl-, -ethoxycarbonyl-β-ethoxy-N-ethoxycarbonylacrylamides.     

Selective synthesis of allylated oxime ethers and nitrones based on palladium-catalyzed allylic substitution of oximes

[reaction: see text] The viability of oximes as nucleophiles in transition-metal-catalyzed allylic substitution was examined. The oxygen atom of oxime acted as a reactive nucleophile in the reaction of a pi-allyl palladium complex. In the presence of Pd(PPh3)4, the allylic substitution of oximes with allylic carbonate afforded the linear O-allylated oxime ethers selectively without a base. In contrast, the palladium-catalyzed reaction with allylic acetate proceeded smoothly in the presence of K2CO3 or Et2Zn as a base. Selective formation of nitrones was achieved by using palladium(II) catalyst. In the presence of Pd(cod)Cl2, the allylic substitution of oximes with allylic acetate afforded the N-allylated nitrones under solvent-free conditions, as a result of the reaction with the nitrogen atom of oximes.     

Decolorization of Distillery Effluent Using Poly(Vinyl Chloride) and Cellulose Acetate Phthalate as Adsorbents

Decolorization of distillery effluents, using low cost polymer adsorbents, is one of the challenging areas for environmental technologists. Untreated distillery effluents are harmful to the environment, causing foul smell, spoiling fresh water sources and killing aquatic life. The color of distillery effluents have been decolorized by using polymer based adsorbents, such as poly(vinyl chloride) (PVC) and cellulose acetate phthalate (CAP), which are water insoluble, easily available, and cheap. In the present article, special emphasis is given to studies such as the effect of contact time, dosage amount, dilution, and the variation in the amount of sample on the degree of decolorization of the effluent. The decolorization of a distillery effluent was monitored by using UV/Visible spectroscopy and Fourier transform infrared spectroscopy (FTIR). From these studies, it was noticed that moderate to fair results were obtained and it was also found that CAP was a better adsorbent, compared to PVC, for decolorization of distillery effluents.