Self-repairing polymers: poly(dioxaborolane)s containing trigonal planar boron

The molecular weight of poly(dioxaborolane)s can be controlled during the polymerization reaction or through post-polymerization processing in such a manner that hydrolytic damage to these materials may be repaired, thereby regenerating the polymer.     

尼龙—6／丙烯酸接枝膜的结构与性能

应用ＩＲ确定了尼龙－６与丙烯酸接枝反应的接枝点位于尼龙大分子酰胺键的Ｎ原子上，用Ｘ射线衍射研究了接枝膜的结晶状况，探讨了接枝率对接枝膜的电阻、离子交换容量、强度等性能的影响．     

红细胞膜上各种磷脂中脂肪酸的测定

应用自制硅胶板的薄层色谱法分离了红细胞膜上四种主要磷脂。将分离后的每种磷脂斑点硅胶涂层刮下，不经萃取，直接在无水甲醇－苯－乙酰氯溶液中进行转移甲基化，然后用毛细管相色谱分离测定其脂肪酸组成和含量。上述方法已成功地用于先天愚型病人和正常人红细胞膜上各种磷脂中脂肪酸轮廓分析，获得有意义的结果。     

Electronic structure and intrinsic redox properties of [2Fe-2S]+ clusters with tri- and tetracoordinate iron sites

Using potentially bidentate ligands (-SC2H4NH2), we produced [2Fe-2S]+ species of different coordination geometries by fission of [4Fe-4S]2+ complexes. Even though the ligands are monodentate in the cubane complexes, both mono- and bidentate complexes were observed in the [2Fe] fission products through self-assembly because of the high reactivity of the tricoordinate iron sites. The electronic structure of the [2Fe] species was probed using photoelectron spectroscopy and density functional calculations. It was found that tetracoordination significantly decreases the electron binding energies of the [2Fe] complexes, thus increasing the reducing capability of the [2Fe-2S]+ clusters.     

Tracking the optical mass centroid of single electroactive nanoparticles reveals the electrochemically inactive zone

The inevitable microstructural defects, including cracks, grain boundaries and cavities, make a portion of the material inaccessible to electrons and ions, becoming the incentives for electrochemically inactive zones in single entity. Herein, we introduced dark field microscopy to study the variation of scattering spectrum and optical mass centroid (OMC) of single Prussian blue nanoparticles during electrochemical reaction. The “dark zone” embedded in a single electroactive nanoparticle resulted in the incomplete reaction, and consequently led to the misalignment of OMC for different electrochemical intermediate states. We further revealed the dark zones such as lattice defects in the same entity, which were externally manifested as the fixed pathway for OMC for the migration of potassium ions. This method opens up enormous potentiality to optically access the heterogeneous intraparticle dark zones, with implications for evaluating the crystallinity and electrochemical recyclability of single electroactive nano-objects.

The schematic of single cubic-shaped Prussian blue (PB) mesocrystals formed by the oriented aggregation of small nanocrystals. The dark-field images of single PB nanoparticle at PB and Prussian white (PW) states, respectively.     

Investigation of ultraviolet curable waterborne polyurethane acrylate dispersion based on hydroxyl-terminated polybutadiene

A new kind of ultraviolet (UV) curable waterborne polyurethane acrylate dispersion was synthesized based on hydroxyl-terminated polybutadiene (HTPB), poly-(propylene glycol) (PPG), isophorene diisocyanate (IPDI), 2-hydroxy ethyl acrylate (HEA) and dimethylol propionic acid (DMPA) after neutralizing by triethylamine (TEA). 2-Hydroxy-1-[4-2-hydroxyethoxy) phenyl]-2-methyl-1-propanone (Irgacure 2959) was used as a photoinitiator and deionized water as a diluent. Fourier transform infrared (FTIR) analysis was used to identify the chain structure of the UV-curable polyurethane prepolymer based on HTPB and the curing process. Effects of relative content of HTPB and PPG on emulsion stability, resistance to water and ethanol, thermal stability, compatibility of soft and hard segment, as well as the mechanical property of the cured film were investigated. Translated from Polymer Materials Science and Engineering, 2006, 22(3): 199–203 (in Chinese)     

极性有机化合物在电解质水溶液中盐效应的研究(II)应用Pitzer方程关联二(2-乙基已基)磷酸在碱金属氯化物水溶液中的活度系数

本文将用放射性磷32标记法测得的二(2-乙基己基)磷酸在碱金属氯化物水溶液(LiCl、NaCl、KCl、RbCl、CsCl和NH_4Cl)中的溶解度数据~[1], 分别用Pitzer(1973年)方程和Pitzer-Li(1983年)方程进行活度系数的关联. 计算结果表明, 由于Pitzer-Li方程考虑了溶质-溶剂间的短程作用能, 所得参数更能反映盐效应的本质, 故优于Pitzer方程. 同时还表明, 上述体系中离子-水之间的作用能远大于离子-有机化合物之间的作用能。     

Synthesis of beta-substituted alpha-amino acids via Lewis acid promoted enantioselective radical conjugate additions

[Chemical reaction: See text] Lewis acid promoted radical conjugate additions to beta-substituted alpha,beta-unsaturated alpha-nitro esters and amides were investigated. With achiral Lewis acids, there was competition between the desired radical conjugate addition and undesired alkene reduction mediated by Bu3nH. Zinc Lewis acids provided the greatest amounts of addition products with both substrate classes. Studies with Bu3nD indicated that the acidic alpha-stereocenter of the alpha-nitro ester products does not racemize under controlled workup conditions. The corresponding alpha-nitro amides racemized significantly during chromatography, but this problem could be greatly minimized by subjecting the crude adducts to subsequent transformations. Indium-mediated reduction of the nitro group followed by acylation of the resulting amine provided good yields of beta-substituted alpha-amino acid derivatives with mimimal levels of racemization. Attempts to use chiral Lewis acids in a stereoselective variant of this process revealed that Kanemasa's DBFOX/Ph ligand (14a) was uniquely effective. Moderate to good ee's and low dr's were obtained with amide substrates. Determination of the absolute configurations of the syn and anti isomers of adduct 7b showed that the hydrogen atom abstraction step was significantly more stereoselective than the radical conjugate addition step. A model for substrate binding to the chiral Lewis acid is presented.     

Prenylated isoflavones with potential antiproliferative activities from Mappianthus iodoides

Abstract

A phytochemical investigation on the stems of Mappianthus iodoides led to the isolation of a new naturally occurring prenylated isoflavone, mappianthone A (1), together with seven known analogues (2?8). The structure of 1 was elucidated by extensive spectroscopic methods and the known compounds were identified by comparison with data reported in the literature. All isolated compounds were evaluated for their antiproliferative activities against five human cancer cell lines: HL-60, SMMC-7721, A-549, MCF-7 and SW480 in vitro. Compounds 1?8 showed significant antiproliferative effects against several human cancer cell lines with IC₅₀ values ranging from 0.16 to 12.68?μM.

     

Electrochemical Behavior of Epinephrine at a Penicillamine Self-Assembled Gold Electrode,and its Analytical Application

The fabrication and electrochemical characteristics of a penicillamine (PCA) self-assembled monolayer modified gold electrode were investigated. The self-assembled electrode shows obvious electrocatalytic activity for the oxidation of epinephrine (EP). In phosphate buffer (pH 7.73), a sensitive oxidation peak was observed at 0.190V with the PCA modified Au electrode. The peak current is proportional to the concentration of EP in the range of 2.0×10^–56.0×10^–4molL^–1 and 5.0×10^–6 2.0×10^–4molL^–1 for cyclic voltammetry (CV) and differential pulse voltammetry (DPV) with the detection limits of 1.8×10^–7 and 1.3×10^–7molL^–1, respectively. The possible reaction mechanism is also discussed. The PCA self-assembled monolayer modified gold electrode is highly stable and can be applied to the determination of EP in practical injection samples. Application is simple, rapid and produces accurate results.