毛细管电泳安培检测扑热息痛及其水解物

研究了各种电化学预处理条件下碳纤维电极对扑热息痛及水解物的电化学行为。确定该体系最佳预处理条件为０．２Ｖ电位下阳极化１ｍｉｎ，再于－２．０Ｖ下阴极化１０ｓ。预处理后的碳纤维伏安响应得到明显提高。运用最佳条件并在支持电解中加入添加剂后，扑热息痛及其水解物在毛细管电泳上获得很好的分离和检测。其中扑热息痛的检测下限为２．７８ｐｇ；对氨基酚为１．８４ｐｇ。     

病态分析体系有偏估计的研究

运用广义岭估计和Ｌｉｕｋｅｊｉａｎ提出的有偏估计，对病态分析体系进行了数值模拟和实际光度测定，结果表明，广义岭估计显优于最小二乘估计，Ｌｉｕｋｅｊｉａｎ法有功效，可和为解析病态分析体系的化学计量学方法。     

现代免疫分析技术研究进展

本文着重分析了各种标记免疫分析方法的发展状况，指出更多的非同位素标记物的使用，自动化分析等将是免疫分析法的未来发展趋势。     

A modified QuEChERS-gas chromatography-mass spectrometry method for the determination of pesticide residues in Lonicera japonicae FlosEI北大核心CSCD

A modified QuEChERS-gas chromatography-mass spectrometry method using multi-walled carbon nanotubes （MWCNTs）as adsorbent was established for the determination of 72 pesticide residues in Lonicera japonicae Flos. The sample was extracted with Association of Official Agricultural Chemists （AOAC）extracting package,purified with MWCNTs-modified purification tube,analyzed with dynamic multiple reaction monitoring mode,and quantified with external standard method of matrix-matched standard curve. The 72 pesticides showed good linearities in the corresponding concentration ranges with correlation coefficients greater than 0.9936. The limits of detection were 0.001-0.178 μµg/kg,and the limits of quantitation were 0.002-0.593 μµg/kg. The average recoveries for four spiked levels ranged from 60.1% to 118.0%,with the relative standard deviations of 2.2%-17%. © 2023, Youke Publishing Co.,Ltd. All rights reserved.     

Determination of lanthanum and cerium in cmsx-4 nickel-based superalloys by inductively coupled plasma mass spectrometryEI北大核心CSCD

CMSX-4 is the second-generation nickel-based single crystal superalloy used widely in the world. The oxidation resistance and corrosion resistance of CMSX-4 alloy can be improved by adding trace lanthanum (La), cerium (Ce) and other rare earth elements. A method for the simultaneous determination of La and Ce in CMSX-4 nickel-based superalloy by wet dissolution-inductively coupled plasma mass spectrometry was established. The sample was heated and dissolved under normal pressure by aqua regia and hydrofluoric acid, and the interference of fluorine ion was eliminated by using perchloric acid. The amount of dissolved acid and the digestion conditions were optimized. The limits of detection were 0.23 μg/g for La and 0.85 μg/g for Ce under optimized conditions. The spiked recoveries were 95.0%–98.9% with the relative standard deviations of 1.3%–3.9%, which can meet the requirements of accurate and rapid determination of La and Ce in CMSX-4 nickel-based superalloy. © 2023, Youke Publishing Co.,Ltd. All rights reserved.     

A fluorescence enhanced probe for sulfur dioxide detection and fluorescence imaging in living cellsEI北大核心CSCD

基于香豆素和苯并吡啶基团,构建了用于二氧化硫(SO_(2))高效检测的荧光探针P1,其化学结构通过核磁氢谱(^(1)H NMR)、碳谱(^(13)C NMR)和高分辨质谱(HR-MS)确证。在缓冲溶液体系中,单独的探针P1具有微弱的荧光,识别SO_(2)后荧光发射强度明显增强,能够实现对SO_(2)的专一性裸眼识别,检出限为126 nmol/L。生物应用实验结果表明,该探针具有较低的细胞毒性,可用于生物活细胞中外源性SO_(2)的荧光成像。     

羟丙基甲基纤维素作为水泥添加剂研究(四)

以萘磺酸甲醛缩合物为分散剂，水溶性羟丙基甲基纤维素衍生物为粘稠剂，研究了它们的混合物对混凝土材料的分散性与粘稠性及其它性能的影响，并探索了其作用机理。