The choice for radial projections of classic data envelopment analysis (DEA) models, resulting in a number of projections onto the Pareto-inefficient portion of the frontier, has been seen lately as a disadvantage in DEA. The search for a non-radial projection method resulted in developments such as preference structure models. These models consider a priori preference incorporation, using weights in the search for the most preferred efficient target, although presenting some implementation difficulties. In this paper, we propose a multi-objective approach that determines the bases for a posteriori preference incorporation, through individual projections of each variable (input or output) as an objective function, thus allowing one to obtain a target at every extreme-efficient point on the frontier. This multi-objective approach is shown to be equivalent to the preference structure models, yet presenting some advantages, such as the mapping of the possible weights, assigned to partial efficiencies of an observed unit, in order to reach a specific target. 相似文献
This paper presents an approach using a recursive algorithm for packing (?, w)-rectangles into larger rectangular and L-shaped pieces. Such a problem has actual applications for non-guillotine cutting and pallet/container loading. Our motivation for developing the L-approach is based on the fact that it can solve difficult pallet loading instances. Indeed, it is able to solve all testing problems (more than 20 000 representatives of infinite equivalence classes of the literature), including the 18 hard instances unresolved by other heuristics. We conjecture that the L-approach always finds optimum packings of (?, w)-rectangles into rectangular pieces. Moreover, the approach may also be useful when dealing with cutting and packing problems involving L-shaped pieces. 相似文献
The classical Gauss code problem asks to characterize which cyclic sequences arise as the vertex sequence of the straight-ahead path of a 4-regular graph embedded in the plane This problem is generalized to certain 4 regular graphs in arbitrary surfacesA characterization is given for the existence of a 4-regular graph in a specified surface yielding the specified sequence This characterization is obtained using a generalization of Shank's left-right paths 相似文献
This paper presents an application of the integration between Geographical Information Systems (GIS) and Multi-Criteria Decision Analysis (MCDA) to aid spatial decisions. We present a hypothetical case study to illustrate the GIS–MCDA integration: the selection of the best municipal district of Rio de Janeiro State, Brazil, in relation to the quality of urban life. The best municipal district is the one that presents the closest characteristics to those considered ideal by the decision-maker. The approach adopted is the Multi-Objective Linear Programming (MOLP) and the chosen method is the Pareto Race. 相似文献
To assess the integration of an autologous composite fascia and fat graft implanted into the lamina propria of a porcine vocal fold using two different approaches.
Study Design
An experimental prospective study on the porcine larynx was conducted at a tertiary research institution.
Methods
An external cervical approach was used to expose the thyroid cartilage of 24 healthy minipigs under general anesthesia. The composite fascia/fat graft was implanted through two distinct approaches, transmuscular and submuscular. Animals were sacrificed at 7, 30, 90, and 180 days for macroscopic and histological study of the larynx. Graft integration and local inflammatory response were studied.
Results
The survival rate of the experimental model was 100% and all animals had local inflammatory response to the surgical procedure. Only 41.7% of the grafts placed inside the thyroarytenoid (TA) muscle fibers were identified postmortem, whereas 83.3% of the submuscular grafts remained intact.
Conclusions
Graft incorporation was better and there was less inflammation when the architecture of the TA muscle fibers was preserved. Graft extrusion was observed in the most of the cases where it was placed inside the muscle. 相似文献
Over the past decades, the GROMOS force field for biomolecular simulation has primarily been developed for performing molecular dynamics (MD) simulations of polypeptides and, to a lesser extent, sugars. When applied to DNA, the 43A1 and 45A3 parameter sets of the years 1996 and 2001 produced rather flexible double-helical structures, in which the Watson-Crick hydrogen-bonding content was more limited than expected. To improve on the currently available parameter sets, the nucleotide backbone torsional-angle parameters and the charge distribution of the nucleotide bases are reconsidered based on quantum-chemical data. The new 45A4 parameter set resulting from this refinement appears to perform well in terms of reproducing solution NMR data and canonical hydrogen bonding. The deviation between simulated and experimental observables is now of the same order of magnitude as the uncertainty in the experimental values themselves. 相似文献
The aim of this study was to determine the palynological origin, phenolic and flavonoid content, and antioxidant properties of twenty-five samples of bee pollen harvested during a nine-month period (February-November) from the Canavieiras municipality (northeastern Brazil). Of the 25 samples analyzed, only two (February 01 and 02) were heterofloral. The predominant pollens in the samples analyzed during that month were: Cecropia, Eucalyptus, Elaeis, Mimosa pudica, Eupatorium, and Scoparia. Ethyl acetate fractions were analyzed by HPLC-DAD. The flavonoids isoquercetin, myricetin, tricetin, quercetin, luteolin, selagin, kaempferol, and isorhamnetin were detected. The flavonoid present in all 22 samples was isolated and identified as isorhamnetin 3-O-b-neohesperidoside. The total phenolic contents determined using the Folin-Ciocalteu reagent ranged from 41.5 to 213.2 mg GAE/g. Antioxidant activities based on the 1,1-diphenyl-2-picryl hydrazyl (DPPH), 2,2-azinobis 3-ethylbenzothiozoline-6-sulfonic acid (ABTS), and Fe2+ ion chelating activity assays were observed for all extracts, and correlated with the total phenolic content. 相似文献
Being able to participate in the reverse cholesterol transport (RCT), high density lipoproteins (HDL) are known to be anti-atherogenic. In order to understand such a process, it is thus essential to have a detailed knowledge of the structure and molecular organisation of HDL.
Reconstituted nascent high density lipoproteins (r-HDL), consisting of synthetic phospholipids together with different apolipoproteins (apo A-I, A-IV and E), were thus analysed by scanning tunnelling microscopy (STM).
Both shape and dimensions of the discoidal HDL particles measured by this technique were found in good agreement with the data available from the literature.
The accuracy of the STM pictures presented in this paper enables for the first time the visualisation of the molecular organisation of such macromolecules. The arrangement of the protein as antiparallel helical segments, is consistent with the general mode of organisation of apolipoprotein/phospholipid discoidal particles previously reported. 相似文献