全文获取类型
收费全文 | 204205篇 |
免费 | 1712篇 |
国内免费 | 593篇 |
专业分类
化学 | 102339篇 |
晶体学 | 3340篇 |
力学 | 9289篇 |
综合类 | 5篇 |
数学 | 22510篇 |
物理学 | 69027篇 |
出版年
2021年 | 1659篇 |
2020年 | 1797篇 |
2019年 | 2000篇 |
2018年 | 2702篇 |
2017年 | 2601篇 |
2016年 | 3766篇 |
2015年 | 2307篇 |
2014年 | 3614篇 |
2013年 | 9088篇 |
2012年 | 7246篇 |
2011年 | 8739篇 |
2010年 | 6047篇 |
2009年 | 5913篇 |
2008年 | 7914篇 |
2007年 | 8082篇 |
2006年 | 7724篇 |
2005年 | 6894篇 |
2004年 | 6431篇 |
2003年 | 5651篇 |
2002年 | 5499篇 |
2001年 | 6426篇 |
2000年 | 4933篇 |
1999年 | 3794篇 |
1998年 | 3039篇 |
1997年 | 3047篇 |
1996年 | 2792篇 |
1995年 | 2614篇 |
1994年 | 2463篇 |
1993年 | 2340篇 |
1992年 | 2691篇 |
1991年 | 2673篇 |
1990年 | 2600篇 |
1989年 | 2398篇 |
1988年 | 2451篇 |
1987年 | 2450篇 |
1986年 | 2280篇 |
1985年 | 2961篇 |
1984年 | 3215篇 |
1983年 | 2632篇 |
1982年 | 2802篇 |
1981年 | 2772篇 |
1980年 | 2639篇 |
1979年 | 2727篇 |
1978年 | 2821篇 |
1977年 | 2819篇 |
1976年 | 2887篇 |
1975年 | 2670篇 |
1974年 | 2644篇 |
1973年 | 2776篇 |
1972年 | 1763篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
961.
A H van Gennip J Grift E J van Bree-Blom D Ketting S K Wadman 《Journal of chromatography. A》1979,163(4):351-362
Chromatographic characteristics of urinary metabolites of theophylline were studied by two-dimensional thin-layer chromatography, high-performance liquid chromatography and gas chromatography--mass spectrometry. Quantitative date for the urinary metabolites of theophylline in asthmatic children are given. It was shown that 1,3-dimethyluric acid is the predominant excretory product. In addition, smaller amounts of 1-methyluric acid, 3-methylxanthine and unchanged theophylline were found. Excretory patterns after theophylline ingestion before and during the administration of allopurinol in asthma patients and in rats suggest the existence of three metabolic pathways of theophylline. The administration of this drug to a patient with xanthine oxidase of theophylline. The administration of this drug to a patient with xanthine oxidase deficiency resulted in the excretion of 1-methyluric acid in addition to 1,3-dimethyluric acid, 3-methylxanthine, 1-methylxanthine and unchanged theophylline. It was concluded that in man the oxidation of theophylline is not catalysed by xanthine oxidase. 相似文献
962.
963.
964.
V. D. Dyachenko S. G. Krivokolysko V. N. Nesterov Yu. T. Struchkov V. P. Litvinov 《Russian Chemical Bulletin》1996,45(10):2405-2410
The reaction of cyano(cyclohexylidene)thioacetamide with cyanothioacetamide or malononitrile andN-methylmorpholine yieldsN-methylmorpholinium 6-amino-3,5-dicyano-1,4-dihydropyridine-4-spirocyclohexane-2-thiolate. Its structure was established based on the results of alkylation and X-ray structural analysis.Deceased.Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 10, pp. 2535–2540, October, 1996. 相似文献
965.
Karmarkar S Koberda M Momani J Kotecki D Garber R 《Journal of chromatography. A》2004,1039(1-2):147-153
In this paper we describe the development and validation of a solid-phase extraction procedure, followed by ion-exclusion chromatographic determination of citrate and acetate in medical fluids. The medical fluids contained trace levels of non-polar compounds, which were not of interest for the purposes of assay requirements, but due to their strong affinity towards the ion-exclusion chromatography column necessitated a 180-min long runtime to elute. The developed SPE procedure, based on trapping the hydrophobic compounds, on a reversed-phase material, while allowing analytes of interest elute off unretained, shortened the runtime to 35 min. The procedure is simple since it has only two steps, conditioning of the SPE cartridge with acetonitrile and treating the sample. The SPE procedure followed by ion-exclusion chromatographic determination was successfully validated per the International Conference on Harmonization (ICH) guidelines in terms of specificity, accuracy as recovery versus untreated sample, precision, range, linearity of response, ruggedness, stability of treated samples, and robustness. The validation data showed that the method is specific, accurate, precise, rugged, and robust. The validated method has been routinely used in the manufacturing environment. 相似文献
966.
The current status, trends, and a specific role for macroligands in catalysis by heterogenized metallopolymeric complexes are considered. Relations between homogeneous catalysis, enzyme catalysis, and catalysis by heterogenized metal complexes are traced. The effects of various factors on the catalysis of the main reactions used in organic synthesis—hydrogenation, polymerization (in particular, under the action of immobilized metallocene and postmetallocene catalysts), and redox processes (such as the catalysis of oxygenation, hydroperoxide oxidation, epoxidation, and hydroformylation)—are analyzed. In this review, attention is focused on the nondestructive identification of intermediates and catalytically active species in heterogenized systems. Experimental evidence is presented in support of the fact that the high activity, stability, and selectivity of immobilized catalysts are associated with a dramatic inhibition of concerted reactions in the coordination sphere of a transition metal, which result in catalyst deactivation, as well as with substrate enrichment. Prospects for the development of these highly organized hybrid systems and possibilities to consider the main requirements imposed on metal complex catalysis even at the stage of designing them are predicted. 相似文献
967.
V. D. Orlov N. V. Getmanskii O. V. Shishkin E. E. Lakin V. P. Kuznetsov 《Chemistry of Heterocyclic Compounds》1993,29(3):301-306
By the reaction of 2-nitrochalcone with hydrazine hydrate, 5-(2-nitrophenyl)-3-phenyl-1H-2-pyrazoline (I) and the hydrazone of 3-(5-(2-nitrophenyl)-3-phenyl-2-pyrazolin-1-yl)-3-(2-nitrophenyl)propiophenol (II) have been prepared. The acylation of both compounds I and II leads to N-acyl derivatives of the first. The acylating ability of formamide and N,N-dimethylformamide was observed in reactions with pyrazoline I. An x-ray structural study was carried out on compound II.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 360–366, March, 1993. 相似文献
968.
U. Kreibig K. Fauth M. Quinten D. Schönauer 《Zeitschrift für Physik D Atoms, Molecules and Clusters》1989,12(1-4):505-514
First, some general remarks concerning macroscopic “cluster matter” are given. In the second part, three recent, mainly optically and electron-microscopically performed investigations are discussed which deal with special properties of noble metal cluster systems forming the building units of this kind of matter:(1) dressed Au-55 clusters,(2) electromagnetic coupling effects among coagulated clusters,(3) the transition towards compact inhomogeneous matter caused by coalescence of clusters. 相似文献
969.
970.