Prior exposure to an attenuated <Emphasis Type="Italic">Listeria</Emphasis> vaccine does not reduce immunogenicity: pre-clinical assessment of the efficacy of a <Emphasis Type="Italic">Listeria</Emphasis>vaccine in the induction of immune responses against HIV

Background  

We have evaluated an attenuated Listeria monocytogenes (Lm) candidate vaccine vector in nonhuman primates using a delivery regimen relying solely on oral vaccination. We sought to determine the impact of prior Lm vector exposure on the development of new immune responses against HIV antigens.     

Investigation of dibutyl phthalate as plasticizer on poly(methyl methacrylate)–lithium tetraborate based polymer electrolytes

Polymer electrolyte membranes, comprising of poly(methyl methacrylate) (PMMA), lithium tetraborate (Li₂B₄O₇) as salt and dibutyl phthalate (DBP) as plasticizer were prepared using a solution casting method. The incorporation of DBP enhanced the ionic conductivity of the polymer electrolyte. The polymer electrolyte containing 70 wt.% of poly(methyl methacrylate)–lithium tetraborate and 30 wt.% of DBP presents the highest ionic conductivity of 1.58 × 10⁻⁷ S/cm. The temperature dependence of ionic conductivity study showed that these polymer electrolytes obey Vogel–Tamman–Fulcher (VTF) type behaviour. Thermogravimetric analysis (TGA) was employed to analyse the thermal stability of the polymer electrolytes. Fourier transform infrared (FTIR) studies confirmed the complexation between poly(methyl methacrylate), lithium tetraborate and DBP.     

Properties of a vector soliton laser passively mode-locked by a fiber-based semiconductor saturable absorber operating in transmission

We experimentally demonstrate a passively mode-locked fiber laser employing a fiber-based semiconductor saturable absorber (SSA) operating in transmission. Polarization rotation locked vector solitons are observed in the laser. Due to the intrinsic dynamic feature of the laser, period-doubling of these vector solitons has also been observed. Furthermore, extra spectral sidebands are formed on the optical spectrum, caused by the energy exchange between the two orthogonal polarization components of the vector solitons. By careful reduction of the pump power together with fine adjustment to the cavity birefringence, period-one state can further be obtained. Additionally, the phase noise properties of the vector soliton fiber laser have also been characterized experimentally and analytically.     

Growth of Ni2Si by rapid thermal annealing: Kinetics and moving species

The growth kinetics is characterized and the moving species is identified for the formation of Ni₂Si by Rapid Thermal Annealing (RTA) of sequentially deposited Si and Ni films on a 100 Si substrate. The interfacial Ni₂Si layer grows as the square root of time, indicating that the suicide growth process is diffusion-limited. The activation energy is 1.25±0.2 eV in the RTA temperature range of 350–450° C. The results extend those of conventional steady-state furnace annealing quite fittingly, and a common activation energy of 1.3±0.2 eV is deduced from 225° to 450° C. The marker experiment shows that Ni is the dominant moving species during Ni₂Si formation by RTA, as is the case for furnace annealing. It is concluded that the two annealing techniques induce the same growth mechanisms in Ni₂Si formation.     

Talbot interferometer with computer generated gratings

In a Talbot interferometer the self image of a periodic pattern, such as a Ronchi ruling of period d, illuminated by a monochromatic plane wavefront of wavelength λ, is formed at distances which are integral multiples of 2d²/λ. A refracting object placed in front of the Ronchi ruling distorts the self image. A computer generated pattern can be designed, such that, when placed in a self imaging plane, a uniform intensity or a distinct moire pattern characterising a standard object is obtained. A method of computing the required patterns and experimental results for some aspherical objects are described.     

CO oxidation of bare and TiO2-coated NiO-Ni(OH)2 nanoparticles

CO oxidation reactivity of bare and TiO₂-coated nanoparticles consisting of both NiO and Ni(OH)₂ surfaces was studied. For the deposition of TiO₂, atomic layer deposition was used, and formation of three-dimensional domains of TiO₂ on NiO-Ni(OH)₂ could be identified. Based on the data of X-ray Photoelectron Spectroscopy, we suggest that upon TiO₂ deposition only Ni(OH)₂ was remained on the surface, whereas NiO surface disappeared. Both CO adsorption and CO oxidation took place on NiO-Ni(OH)₂ surfaces under our experimental conditions. CO adsorption was almost completely suppressed after TiO₂ deposition, whereas CO oxidation activity was maintained to large extent. It is proposed that bare NiO cannot be active for CO oxidation, and can only uptake CO under our experimental condition, whereas hydroxylated surface of NiO can be active for CO oxidation.     

Annealing-free Poly(3-hexylthiophene):[6,6]-phenyl-C61-butyric acid methyl ester-based organic solar cells

We report on the fabrication of efficient annealing-free organic solar cells using co-solvent solution considered as a promising method for low-cost and time-saving manufacturing. Higher device efficiency could be obtained compared to the pure solvent casted device, resulting from the improved crystallinity, optical absorption and transport properties. The power conversion efficiency of 2.8% was obtained, demonstrating the feasibility of achieving low-cost and high-efficiency organic solar cells without any additional treatment and processing additives.     

Relationship between the 2-body Parameters of the Biswas-Hamann and the Bauer-Maysenholder-Seeger Potential Functions

A theoretical relation between the Bauer-Maysenholder-Seeger (BMS) and the Biswas-Hamann (BH) potential function has been developed herein for the case of 2-body interaction. By equating derivatives of these two potential functions for the 2-body part, a loose form of BMS is expressed in terms of BH parameters with a scaling factor. The validity of the developed parametric relationships has been graphically demonstrated, and the suitability discussed with reference to the extent and direction of bond distortion.     

Genes involved in <Emphasis Type="Italic">Drosophila</Emphasis>glutamate receptor expression and localization

Background  

A clear picture of the mechanisms controlling glutamate receptor expression, localization, and stability remains elusive, possibly due to an incomplete understanding of the proteins involved. We screened transposon mutants generated by the ongoing Drosophila Gene Disruption Project in an effort to identify the different types of genes required for glutamate receptor cluster development.     

Multifractal detrended fluctuation analysis of derivative and spot markets

We investigate the multifractal properties of price increments in the cases of derivative and spot markets. Through the multifractal detrended fluctuation analysis, we estimate the generalized Hurst and the Renyi exponents for price fluctuations. By deriving the singularity spectrum from the above exponents, we quantify the multifractality of a financial time series and compare the multifractal properties of two different markets. The different behavior of each agent-group in transactions is also discussed. In order to identify the nature of the underlying multifractality, we apply the method of surrogate data to both sets of financial data. It is shown that multifractality due to a fat-tailed distribution is significant.