求解带自由面渗流问题移动网格法的改进及其工程应用

采用有限元固定网格和移动网格相结合的方法,求解带自由面的坝体稳定渗流问题。本方法是针对一般坝体的结构,在有限元网格生成之后,又自动生成了网格移动所需的信息,实现了网格在迭代计算中随自由面的变化自动均匀移动;讨论了网格奇异的不同类型,提出了避免单元形状怪异的移动网格方法;在欧拉空间中分区记录坝体不同的渗透性能,在网格移动到新位置后,自动识别网格所在的物性空间,从而确定单元在新位置上的渗流系数。本文将该方法应用到吉林丰满混凝土重力坝防渗加固的实际工程当中,在考虑大坝原有防渗措施的前提下,利用数值分析,研究了防渗芯墙对大坝渗流性能的影响。计算结果表明,加芯墙后坝体自由面位置明显下移,湿水部分大为减少,坝基扬压力没有明显提升,下游出水点位置没有明显下降。计算过程表明,本文方法及措施具有很好的收敛性与稳定性,且收敛性与自由面初始位置的选择无关。     

岩土材料应变局部化的有限元分析方法

采用有限单元法分析岩土材料的应变局部化时经常会遇到单元尺寸敏感性问题和网格锁定问题。自适应网格技术能够有效地解决网格锁定问题,但仍然无法克服计算结果对单元尺寸的依赖性,尽管在一维情况下被证明是可行的。复合体理论(均匀化理论)和弱非连续有限元方法可以成功地解决岩土材料的单元尺寸敏感性问题,在一维情况下两类方法实际上是一致的。本文针对岩土材料应变局部化的有限元新技术所存在的若干问题进行了详细的讨论,并给出了有关算例。     

求解二维三温辐射热传导方程组的一种网格自适应方法

在求解二维三温辐射热传导方程组的过程中,设计了一类新的基于Hessian矩阵的网格自适应算法.数值实验结果表明,与现在流行的基于一阶导数或通量的网格自适应技术相比,该算法能够大幅改善系统的能量守恒误差,并具有较高的整体计算效率.     

细胞松弛素B阻断微核法鉴定男性个体辐射敏感性的方法初探

初步研究了男性个体辐射敏感性的鉴定方法及标准.采集50名男性志愿者的外周血,分别给予不同剂量X射线照射,采用细胞松弛素B阻断双核法测定微核率(MNF),通过二阶多项拟合法,绘制微核剂量效应选项中心标准曲线,将个人微核剂量效应曲线与标准曲线比对后判断个体辐射敏感性.0.0～2.5 Gy剂量范围内,剂量效应二阶多项拟合的中...     

Rapid Detection of Five Estrogens Added Illegally to Dietary Supplements by Combining TLC with Raman Imaging Microscope

Estrogens added illegally to dietary supplements are hazardous to human health. Traditional detection and analysis methods have many limitations, and we have developed an assay that combines thin-layer chromatography with Raman imaging microscopy (TLC-RIM). The five estrogens (estrone, estradiol, estriol, ethinyl estradiol, and diethylstilbestrol) were initially separated by TLC, then detected by area scanning Raman imaging with a 532 nm laser under a microscope. Raman spectra were obtained for each estrogen, which were used for detecting estrogen illegally added to botanical dietary supplements. The LOD of each estrogen was 0.4, 1.0, 0.8, 0.2, and 0.2 mg/mL, respectively. The matrix in the real sample did not interfere with the detection of estrogens. The method was fast, sensitive, stable, specific, and reliable.     

The Potential Antidepressant Action of Duloxetine Co-Administered with the TAAR1 Receptor Agonist SEP-363856 in Mice

Here, we explored the possible interaction between duloxetine and SEP-363856 (SEP-856) in depression-related reactions. The results showed that oral administration of duloxetine showed powerful antidepressant-like effects in both the forced swimming test (FST) and the suspension tail test (TST). SEP-856 orally administered alone also exerted an antidepressant-like effect in FST and TST, especially at doses of 0.3, 1, and 10 mg/kg. In addition, duloxetine (15 mg/kg) and SEP-856 (15 mg/kg) both showed antidepressant-like effects in the sucrose preference test (SPT). Most importantly, in the above experiments, compared with duloxetine alone, the simultaneous use of duloxetine and SEP-856 caused a more significant antidepressant-like effect. It is worth noting that doses of drug combination in FST and TST did not change the motor activities of mice in the open-field test (OFT). Thus, duloxetine and SEP-856 seem to play a synergistic role in regulating depression-related behaviors and might be beneficial for refractory depression.     

荧光分光光度法定量分析OP乳化剂

通过对OP(聚乙二醇辛基苯基醚)乳化剂的荧光光谱研究,发现其在304nm处产生较强的荧光.在pH 5.5的B-R缓冲溶液中,OP乳化剂的荧光强度与其浓度在一定范围内呈良好的线性关系,据此建立了一种新的高灵敏度的测定方法.在0.1-50.0μg/mL的浓度范围内,测定波长λex/λem=226nm/304nm的回归方程为:F=22.12C+9.825(C:μg/mL,r=0.9995),检出限为0.068μg/mL;测定波长λex/λem=276nm/304nm的回归方程为:F=90.08C-10.12 (C:μg/mL,r=0.9999),检出限为0.053μg/mL.采用此两组测定波长对同组样品进行测定,样品回收率均在96.5％以上,对测定结果进行F检验和t检验分析,得出两组数据之间无显著性差异.方法灵敏度高,抗干扰能力较强,可用于测定较复杂环境样品中微量OP乳化剂含量.     

宽带多普勒声纳信号频谱特性分析

宽带多普勒声纳采用重复相位编码技术和脉冲-脉冲相关技术,解决了窄带技术存在的距离分辨力和速度分辨力的矛盾。本文主要研究了重复相位编码信号的频谱特性,并与矩形正弦填充脉冲的频谱进行比较,同时研究了回波信号的频谱特性,推导出频域上的测速公式,并根据回波的频谱特性分析了宽带多普勒声纳产生测速模糊的原因,并提出一种解决测速模糊的方法。     

基于小波变换的磁共振图像去噪

去噪是图像处理中的一个非常重要的问题. 传统去噪方法在降低噪声的同时会模糊图像的细节,基于小波变换的图像去噪方法能在降低图像噪声的同时较好地保持图像的细节,目前基于小波变换对图像进行去噪已经成为最有前途的去噪方法之一. 本文综合小波域去噪的文献,对小波域的磁共振图像去噪方法进行了综述,详细介绍了各种小波域的磁共振图像去噪方法,并对他们的性能进行了总结,对小波域去噪方法的发展趋势进行了展望.     

Pressure dependence of the thermal stability in LiMn2O4

Structural stability in terms of the decomposition temperature in LiMn₂O₄ was systematically investigated by a series of high-temperature and high-pressure experiments.LiMn₂O₄ was found to have structural stability up to 5 GPa at room temperature.Under ambient pressure,the compound decomposed at 1300℃.The decomposition temperature decreased with increasing pressure,yielding more complex decomposed products.Below the decomposition temperature,the crystal structure of LiMn₂O₄ varied with pressure.The presented results in this study offer new insights into the thermal and pressure stability of LiMn₂O₄ materials as a cathode for lithium-ion batteries that can operate under extreme conditions.Therefore,these findings may serve as a useful guide for future work for improving lithium-ion batteries.