A scheme for accurate quantification of 1H spectra is presented. The method uses maximum-phase finite impulse response (FIR) filters for solvent suppression and an iterative nonlinear least-squares (NLLS) algorithm for parameter estimation. The estimation algorithm takes the filter influence on the metabolites of interest into account and can thereby correctly incorporate a large variety of prior knowledge into the estimation phase. The FIR filter is designed in such a way that no distortion of the important initial samples is introduced. The FIR filter method is compared numerically with the HSVD method for water signal removal in a number of examples. The results show that the FIR method, using an automatic filter design scheme, slightly outperforms the HSVD method in most cases. The good performance and ease of use of the FIR filter method combined with its low computational complexity motivate the use of the proposed method. 相似文献
Nonlinear optical vinyl polymers with high glass transition temperature (Tg) were prepared by the functionalization of a fluorinated acrylate‐methyl vinyl isocyanate copolymer. A modified pathway to obtain a thiophene bridged chromophore was worked out. Poled films of the polymers show a fairly high and stable nonlinear optical response, even at elevated temperatures.
The thiophene‐bridged chromophore, based on a substituted dicyanomethylene‐dihydrofuran acceptor, synthesized here. 相似文献
A novel compact low-frequency oscillating hot-wire (OHW) anemometer is calibrated in a custom-built wind tunnel. Laser Doppler anemometry is used for reference velocity measurements, phase-locked with the oscillating wire. Three probe designs are calibrated, examining the influence of prong shape on the wake contamination. Results for two oscillation amplitudes and several frequencies are discussed. Through non-dimensional analysis, the optimum probe design and operating parameters are extracted. The OHW features a maximum measurable negative velocity of −1.0 m/s which is comparable to existing oscillating and flying hot-wire anemometers. The compact OHW can be applied to reversing flow in confined geometries such as flow in exhaust systems.
Tim PersoonsEmail: Phone: +32-16-322511Fax: +32-16-322985
Several algorithms for automatic frequency alignment and quantitation of single resonances in multiple magnetic resonance (MR) spectra are investigated. First, a careful comparison between the complex principal component analysis (PCA) and the Hankel total least squares-based methods for quantifying the resonances in the spectral sets of magnetic resonance spectroscopy imaging (MRSI) spectra is presented. Afterward, we discuss a method based on complex PCA plus linear regression and a method based on cross correlation of the magnitude spectra for correcting frequency shifts of resonances in sets of MR spectra. Their advantages and limitations are demonstrated on simulated MR data sets as well as on an in vivo MRSI data set of the human brain. 相似文献