木质素磺酸钠改性聚砜膜的制备及其在正渗透膜中的应用

采用木质素磺酸钠作为亲水添加剂,通过浸没沉淀相转化法制备了木质素磺酸钠共混改性聚砜膜,以改善聚砜膜的亲水性,并用作正渗透膜的支撑层,以降低内浓差极化效应.利用扫描电子显微镜、衰减全反射傅里叶变换红外光谱仪、水接触角仪等研究了不同木质素磺酸钠添加量对聚砜膜的结构和表面性质的影响.结果表明,添加木质素磺酸钠后,聚砜膜的指状孔变得规整且狭长.水接触角实验证实添加木质素磺酸钠能改善聚砜膜的亲水性,当木质素磺酸钠含量为0.4 wt%时,聚砜膜的表面水接触角可降低至65°.正/反渗透测试装置分别用于表征正渗透膜的传质性质和结构参数.结果表明,以0.4 wt%木质素磺酸钠改性聚砜膜为支撑层的正渗透膜的水渗透性能(A=3.12×10~(-5) LMH×Pa~(-1))优于纯聚砜基底正渗透膜(0.76×10~(-5)LMH×Pa~(-1)),而且前者的结构参数(S=2010mm)远小于后者(3450mm),说明木质素磺酸钠改性聚砜膜有效弱化了正渗透膜的内浓差极化效应.     

基于节点负荷失效的网络可控性研究

Liu和Barabasi将现代控制理论应用到线性系统的网络可控性问题上, 提出了最小驱动节点集的计算方法, 解决了复杂网络控制的可计算问题. 针对现实网络中存在的节点因负荷过载而失效的问题, 本文提出了基于节点负荷失效的网络可控性模型. 通过对网络采用介数和Weibull失效模型, 在随机和目标失效机制下进行仿真, 研究结果表明: 维持无标度网络可控性的难度要明显大于随机网络; 在目标节点失效机制下, 即使对网络输入极少的失效信号, 也能极大地破坏网络的可控性; 使高介数节点失效要比使度高节点失效更能破坏网络的可控性, 说明高介数节点在维持网络可控性上发挥着重要作用; 对不同的负荷失效模型, 要合理采取措施, 防止网络发生阶跃性全不可控现象. 关键词： 网络可控性 结构可控性 节点失效     

Power flow and energy distribution in conservatively or non-conservatively coupled oscillators under correlative excitations

As a foundation of SEA for consevatively or non-conservativelycoupled systems under correlative excitations,power flow and energy distribu-tion in two coupled osillators under proportionally correlative excitations arestudied mainly in this paper.Theoretical relationship among power flow andtime averaged vibational energy of the osillators,as well as power balance equa-tions and energy ratio or them,are derived.Further along,power flow,energydistribution and power balance equations of the systems in conservative ornon-conservative coupling and under proportional correlative excitations arediscussed in detail,with comparing with characteristics of those innon-correlative excitations.Numerical resu1ts supporting the basic theory aregiven,too.Results show that the power flow and energy distribution of theosillators under correlative excitations,either conservative or non-conservativecoupling,are much different to those in the condition of non-correlativeexcitations.     

ω‐Fluoro Thiafatty Acids: New Mechanistic Probes of Desaturase‐Mediated Reactions

A series of 18‐fluoro thiastearates were prepared and incubated with a yeast Δ9‐desaturating system. The relative efficiency of desaturase‐mediated sulfoxidation was monitored via ¹⁹F‐NMR analysis of the sulfoxide products, and a strong preference for oxo transfer to the S‐atom occupying the 9‐position was confirmed. The oxidation profile obtained in this manner matched that of analogous experiments with non‐fluorinated substrates. These results form the basis of a versatile ¹⁹F‐NMR‐based method for mapping the position of the putative diiron oxidant relative to substrate, and has potential application to the study of membrane‐bound desaturases in vitro.     

Customizable Biopolymers for Heavy Metal Remediation

Nanoscale materials have been gaining increasing interest in the area of environmental remediation because of their unique physical, chemical and biological properties. One emerging area of research has been the development of novel materials with increased affinity, capacity, and selectivity for heavy metals because conventional technologies are often inadequate to reduce concentrations in wastewater to acceptable regulatory standards. Genetic and protein engineering have emerged as the latest tools for the construction of nanoscale materials that can be controlled precisely at the molecular level. With the advent of recombinant DNA techniques, it is now possible to create ‘artificial’ protein polymers with fundamentally new molecular organization. The most significant feature of these nanoscale biopolymers is that they are specifically pre-programmed within a synthetic gene template and can be controlled precisely in terms of sizes, compositions and functions at the molecular level. In this review, the use of specifically designed protein-based nano-biomaterials with both metal-binding and tunable properties for heavy metal removal is summarized. Several different strategies for the selective removal of heavy metals such as cadmium and mercury are highlighted.     

A Continuous Time Financial Market with a Poisson Process as Transaction Timer

We study the influence of transactions on investors' portfolio values under the assumption that the investors' transaction times are determined by Poisson point processes, whose intensity measures can naturally be interpreted as transaction frequencies. We give lower and upper bounds on the expectations of portfolio values in terms of transaction intensities, and prove that there exist a sequence of portfolio fractions and a transaction frequency which maximize the expectation of the portfolio value for a finite horizon. We also give bounds on transaction frequencies for preventing the investors from losing money. Then the optimal transaction strategies for finite and infinite time horizons and the asymptotic effects of making transactions are discussed based on the concept of a benefit function of transactions. Finally, we investigate the influence of transactions on financial markets, with the market mean rates of return and volatilities being connected with the transaction frequency. We show that the market becomes unprofitable in a finite time if an overwhelming amount of transactions is involved and the market is suitable for some limited transactions when its trade capacity does not increase beyond any limit at a relatively high speed. Our models and simulations illustrate how the investors' collective action affects the financial market.     

Turning on the Antimicrobial Activity of Gold Nanoclusters Against Multidrug-Resistant Bacteria**

In this work, we show that the addition of thiourea (TU) initiated broad-spectrum antimicrobial activity of otherwise inactive D-maltose-capped gold nanoclusters (AuNC-Mal). For example, AuNC-Mal/TU was effective against multidrug-resistant Pseudomonas aeruginosa with a minimum inhibitory concentration (MIC) of 1 μg mL⁻¹ (2.5 μM [Au]) while having 30–60 times lower in vitro cytotoxicity against mammalian cells. The reaction of AuNC-Mal and TU generated the antimicrobial species of [Au(TU)₂]⁺ and smaller AuNCs. TU increased the accumulation of Au in bacteria and helped maintain the oxidation state as Au^I (vs. Au^III). The modes of action included the inhibition of thioredoxin reductase, interference with the Cu^I regulation and depletion of ATP. Moreover, the antimicrobial activity did not change in the presence of colistin or carbonyl cyanide 3-chlorophenylhydrazone, suggesting that AuNC-Mal/TU was indifferent to the outer membrane barrier and to bacterial efflux pumps.     

Characterization of warfarin unusual peak profiles on oligoproline chiral high performance liquid chromatography columns

Unusual peak profiles of warfarin were characterized on two oligoproline chiral stationary phases (CSPs). The pattern of 1st peak (S(−)) broadening and the 2nd peak (R(+)) compression was observed under mobile phase of hexane (0.1% TFA)/2-propanol (IPA) on a triproline CSP 1, and with other alcohol modifier such as ethanol, 1-propanol, 1-butanol, 2-butanol, and tert-butanol as well. Through analyzing system peak of additives, the unusual peak profile was interpreted by perturbation of TFA additive system peak. The unusual peak profile was also found in enantioseparation of coumachlor and on a covalently bonded doubly tethered diproline CSP 2. The pattern of 1st peak (S(−)) broadening and the 2nd peak (R(+)) compression can change to pattern of 1st peak compression and the 2nd peak broadening from 15 to 50 °C. Chiral separation of warfarin created nonlinear van’t Hoff plots on CSP. No peak broadening/compression were observed with methyl tertiary butyl ether or ethyl acetate as the modifier. The peak shapes of the two warfarin enantiomers can thus be tuned by varying alcohol concentration and column temperature. High separation factor and resolution may be carried out to tune the peak profiles into Langmuir/anti-Langmuir band-shape composition. Using none hydrogen donor modifier may avoid interference of the TFA system peak.