全文获取类型
收费全文 | 162篇 |
免费 | 15篇 |
国内免费 | 1篇 |
专业分类
化学 | 133篇 |
晶体学 | 1篇 |
力学 | 1篇 |
数学 | 28篇 |
物理学 | 15篇 |
出版年
2023年 | 2篇 |
2022年 | 4篇 |
2021年 | 10篇 |
2020年 | 4篇 |
2019年 | 5篇 |
2018年 | 9篇 |
2017年 | 4篇 |
2016年 | 4篇 |
2015年 | 7篇 |
2014年 | 9篇 |
2013年 | 14篇 |
2012年 | 13篇 |
2011年 | 19篇 |
2010年 | 9篇 |
2009年 | 7篇 |
2008年 | 15篇 |
2007年 | 10篇 |
2006年 | 9篇 |
2005年 | 11篇 |
2004年 | 6篇 |
2003年 | 1篇 |
2002年 | 3篇 |
2001年 | 1篇 |
1999年 | 1篇 |
1997年 | 1篇 |
排序方式: 共有178条查询结果,搜索用时 0 毫秒
81.
Hubaud JC Bombarda I Decome L Wallet JC Gaydou EM 《Journal of photochemistry and photobiology. B, Biology》2008,92(2):103-109
We describe the synthesis of eighteen variously substituted 1,3- dibenzoylmethane (1,3-DBM) and their change in absorption spectra depending of the nature of donor or acceptor substituents on one or the two aromatic moieties. These compounds were prepared in two steps starting from the corresponding acetophenones, phenol and benzoyl chlorides. The phenyl benzoate was obtained by condensation of benzoyl chloride with phenol in a classical way. Stirring of the phenyl benzoate and acetophenone in DMSO with powdered sodium hydroxide for a few minutes gave the dibenzoylmethane in yields depending on substituents on the phenyl rings. Changes in absorption of UVA/UVB sunlight of these molecules were observed according to the nature and the position of substituents on the phenyl rings. Molecules 2b (1-phenyl-3-(3,4,5-trimethoxyphenyl)-1,3-propanedione), 2d (1-(3,4-dimethoxyphenyl)-3-phenyl-l,3-propanedione), 2e (1-(2,3-dimethoxyphenyl)-3-phenyl-l,3-propanedione) and 2f (1-(2,3,4-trimethoxyphenyl)-3-phenyl-l,3-propanedione) were the most interesting for cosmetic applications because even after irradiation, they preserve their absorptive in UVA range and also in UVB range The other compounds are too photounstable and so can lose their protective effects. These results showed the lack of phototoxicity of these compounds and the possibility to use them as solar filters. Therefore, variously di- or tri methoxy 1,3-DBM are interesting molecules in term of photoprotection and open new prospects for UVA photostable filters. 相似文献
82.
83.
84.
Simone Matte? Dominique Grevey Alexandre Mathieu Laetitia Kirchner 《Optics & Laser Technology》2009,41(6):665-670
In order to deepen the understanding of the differences between laser and laser-arc hybrid welding, comparisons were undertaken using thermography. The experiments were carried out for a T assembly of aluminium alloy plates. Modelling, based on the finite element method approach, was realized using IR temperature measurements and seam geometry. For a value of the power supply, depicted as a surface source in the hybrid case, agreement was found between simulated and measured temperatures. The arc power supply efficiency value is similar to the usually used value. 相似文献
85.
Laetitia Mespouille Olivier Coulembier Dilyana Paneva Philippe Degée Iliya Rashkov Philippe Dubois 《Journal of polymer science. Part A, Polymer chemistry》2008,46(15):4997-5013
Well‐defined adaptative and amphiphilic polymer conetworks based on hydrophilic poly(N,N‐dimethylamino‐2‐ethyl methacrylate) (PDMAEMA) and hydrophobic poly(ε‐caprolactone) (PCL) have been prepared by combination of ATRP, ROP, and “Click chemistry.” Telechelic α,ω‐alkyne terminated PCL crosslinker was obtained by ring‐opening polymerization (ROP) of CL in THF at 80 °C initiated by 1,4‐butanediol and catalyzed by tin(II) bis 2‐ethyl hexanoate (Sn(Oct)2), followed by the quantitative esterification of hydroxyl end‐groups by activated 4‐pentynoic acid. In parallel, an azido‐containing PDMAEMA‐based copolymer was obtained in a three‐step strategy involving primarily the copolymerization of DMAEMA with newly synthesized 2‐(2‐azidoethoxy)ethyl methacrylate (AEEMA) monomer. The latter was obtained by nucleophilic substitution of chloride atom from 2‐(2‐chloroethoxy)ethanol by an azide group followed by the esterification reaction of the hydroxyl group with methacrylic anhydride. The copolymerization was carried out in an equivolumic mixture of H2O and isopropanol at r.t. and initiated by a ω‐bromoisobutyryl oligo PEO macroinitiator in the presence of various ligated copper(I)‐based catalysts. In a last step, both polymer precursors were chemically linked by the Huisgen‐1,3‐dipolar cycloaddition in anhydrous THF at r.t. using CuBr complexed by 2,2′‐bipyridine ligand as catalyst. Final material was characterized by the means of DSC and SEM, both attesting of a homogeneous distribution of the PCL crosslinkers and a highly porous structure in this new amphiphilic model conetworks. © 2008 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 46: 4997–5013, 2008 相似文献
86.
Hitzbleck M Avrain L Smekens V Lovchik RD Mertens P Delamarche E 《Lab on a chip》2012,12(11):1972-1978
Capillary-driven microfluidics are simple to use and provide the opportunity to perform fast biological assays with nanogram quantities of reagents and microliters of sample. Here we describe capillary soft valves (CSVs) as a simple-to-implement and -actuate approach for stopping liquids in capillary-driven microfluidics. CSVs are inserted between wettable microstructures and work to block liquids owing to a capillary pressure barrier of a few kPa. This barrier is suppressed by pressing down the soft cover of the CSV using, for example, the tip of a pen. CSVs comprise a hard layer (in silicon or polymer) with wettable microstructures and a soft cover made of poly(dimethylsiloxane) (PDMS) here. CSVs have a footprint as small as 0.6 mm(2). We illustrate how these valves work in the context of detecting DNA analytes. Specifically, a dsDNA target (997 bp PCR product, non-purified) was detected at concentrations of 20 and 200 nM in a sample volume of 0.7 μL and within 10 min. The assay includes melting of the dsDNA at 95 °C, annealing of a 30-base biotinylated probe at 50 °C, and intercalation of a fluorescent dye into the re-hybridized dsDNA at 25 °C. Actuation of the CSV allows the DNA target-probe-dye complexes to flow over 100 μm wide, streptavidin receptor lines. This work suggests that CSVs can fulfil the requirements set by complex assays, in which elevated temperatures and reaction with probes, dyes and capture species are needed. CSVs therefore greatly complement capillary-driven microfluidics without adding significant design, fabrication and actuation issues. 相似文献
87.
Antonelle Pardo Laetitia Mespouille Philippe Dubois Pierre Duez Bertrand Blankert 《Central European Journal of Chemistry》2012,10(3):751-765
One of the most promising separation techniques that have emerged during the last decade is based on the use of molecularly
imprinted polymers (MIPs). MIPs are stable polymers that possess specific cavities designed for a template molecule, endowed
with excellent selectivity compared to regular solid phase extraction techniques. Molecularly imprinted solid-phase extraction
(MISPE) has already shown a high efficiency for the sample preparation from complex matrices. Natural products received huge
attention in recent years. Indeed, the application of MISPE for the screening of natural products appears extremely interesting
not only for the selective extraction of a target compound but also for the concomitant discovery of new drug candidates,
promising sources of therapeutic benefits. In the present review, examples of recognition and separation of active components
from natural extracts are emphasized. MIPs are very promising materials to mimic the recognition characteristics exhibited
by enzymes or receptors although further developments are necessary to fully exploit their wide potential. 相似文献
88.
89.
Malkoch M Vestberg R Gupta N Mespouille L Dubois P Mason AF Hedrick JL Liao Q Frank CW Kingsbury K Hawker CJ 《Chemical communications (Cambridge, England)》2006,(26):2774-2776
New PEG-based hydrogel materials have been synthesized by Click chemistry and shown to result in well-defined networks having significantly improved mechanical properties; the selectivity of the azide/acetylene coupling reaction also allows for the incorporation of various additives and functional groups leading to chemical tailoring of the hydrogels. 相似文献
90.