全文获取类型
收费全文 | 298篇 |
免费 | 17篇 |
国内免费 | 5篇 |
专业分类
化学 | 183篇 |
力学 | 6篇 |
数学 | 60篇 |
物理学 | 71篇 |
出版年
2022年 | 5篇 |
2021年 | 2篇 |
2020年 | 5篇 |
2019年 | 3篇 |
2018年 | 5篇 |
2017年 | 4篇 |
2016年 | 10篇 |
2015年 | 6篇 |
2014年 | 5篇 |
2013年 | 6篇 |
2012年 | 19篇 |
2011年 | 35篇 |
2010年 | 19篇 |
2009年 | 6篇 |
2008年 | 22篇 |
2007年 | 20篇 |
2006年 | 19篇 |
2005年 | 11篇 |
2004年 | 15篇 |
2003年 | 8篇 |
2002年 | 7篇 |
2001年 | 7篇 |
2000年 | 3篇 |
1999年 | 6篇 |
1998年 | 1篇 |
1997年 | 1篇 |
1996年 | 1篇 |
1995年 | 2篇 |
1994年 | 1篇 |
1993年 | 5篇 |
1992年 | 3篇 |
1991年 | 4篇 |
1990年 | 4篇 |
1989年 | 4篇 |
1988年 | 4篇 |
1987年 | 3篇 |
1986年 | 8篇 |
1985年 | 5篇 |
1984年 | 4篇 |
1983年 | 5篇 |
1982年 | 3篇 |
1981年 | 2篇 |
1980年 | 1篇 |
1979年 | 2篇 |
1978年 | 1篇 |
1977年 | 1篇 |
1976年 | 1篇 |
1975年 | 2篇 |
1974年 | 1篇 |
1973年 | 3篇 |
排序方式: 共有320条查询结果,搜索用时 15 毫秒
71.
Transition metal-catalyzed [m+n+o] carbocyclization reactions provide powerful methods for the construction of complex polycyclic systems that are generally not accessible through classical pericyclic reactions. We have developed the first regio- and enantioselective crossed intermolecular rhodium-catalyzed [2+2+2] carbocyclization of carbon- and heteroatom-tethered 1,6-enynes with unsymmetrical 1,2-disubstituted alkynes. This study clearly delineates the ligand requirements for obtaining excellent regio- and enantioselectivity. Furthermore, the ability to utilize various electron-withdrawing groups, and to introduce quaternary carbon stereogenic centers, provides the level of versatility necessary for its application to target-directed synthesis. Additional studies on the development and application of this novel methodology to the total synthesis of natural products are currently underway. 相似文献
72.
Label-free cell separation and sorting in microfluidic systems 总被引:2,自引:0,他引:2
Daniel R. Gossett Westbrook M. Weaver Albert J. Mach Soojung Claire Hur Henry Tat Kwong Tse Wonhee Lee Hamed Amini Dino Di Carlo 《Analytical and bioanalytical chemistry》2010,397(8):3249-3267
Cell separation and sorting are essential steps in cell biology research and in many diagnostic and therapeutic methods. Recently,
there has been interest in methods which avoid the use of biochemical labels; numerous intrinsic biomarkers have been explored
to identify cells including size, electrical polarizability, and hydrodynamic properties. This review highlights microfluidic
techniques used for label-free discrimination and fractionation of cell populations. Microfluidic systems have been adopted
to precisely handle single cells and interface with other tools for biochemical analysis. We analyzed many of these techniques,
detailing their mode of separation, while concentrating on recent developments and evaluating their prospects for application.
Furthermore, this was done from a perspective where inertial effects are considered important and general performance metrics
were proposed which would ease comparison of reported technologies. Lastly, we assess the current state of these technologies
and suggest directions which may make them more accessible. 相似文献
73.
Kwong FY Li YM Lam WH Qiu L Lee HW Yeung CH Chan KS Chan AS 《Chemistry (Weinheim an der Bergstrasse, Germany)》2005,11(13):3872-3880
An interesting rhodium-catalyzed asymmetric aqueous Pauson-Khand-type reaction was developed. A chiral atropisomeric dipyridyldiphosphane ligand was found to be highly effective in this system. This operationally simple protocol allows both catalyst and reactants to be handled under air without precautions. Various enynes were transformed to the corresponding bicyclic cyclopentenones in good yield and enantiomeric excess (up to 95 % ee). A study of the electronic effects of the enyne substrates revealed a correlation between the electronic properties of the substrates and the ee value obtained in the product of the Pauson-Khand-type reaction. A linear free-energy relationship was observed from a Hammett study. 相似文献
74.
75.
Cheng C Shi Y Zhu C Li W Wang L Fung KK Wang N 《Physical chemistry chemical physics : PCCP》2011,13(22):10631-10634
We report a direct precipitation method for mass production of ZnO microflowers (MFs) containing hierarchical structures. The ZnO MFs are constructed by interlaced single crystalline and porous nanosheets which are ideal photoanode material for dye-sensitized solar cells (DSCs) because the MFs can largely improve the energy harvesting performance and the efficiency of DSCs. Compared with other forms of nano-sized structures, the novel hierarchical structures show obvious advantages in DSC application because of their large surface area for dye-loading, good light scattering efficiency and excellent electrical transport property. The quasi-solid state DSCs fabricated with the MF hierarchical structures exhibited an efficiency of 4.12%, much higher than that of ZnO nanoparticle-based DSCs, indicating a great potential for the development of highly-efficient quasi-solid DSCs. 相似文献
76.
The biomorphic CuO/CeO2/Al2O3 was used as a catalyst in methanol steam reforming (SRMe), and the reaction mechanism was studied. It was found that the oxidation states of Cu in the biomorphic sample would vary with the reaction temperature and they also affected the rate of the reaction. Below 200 °C, SRMe would not occur, and the X-ray diffractometry study indicated that the CuO/CeO2/Al2O3 sample remained unchanged. Above 200 °C, the SRMe occurred when CuO started to be reduced to Cu. As the reaction temperature increased, Cu reacted with CO2 and led to the formation of Cu2O during the reversed water gas shift reaction. Above 250 °C, the conversion of MeOH to CO2 and H2 reached to a saturation of 95% even if the amount of metallic Cu was reduced to half of its original portion. This confirmed that both Cu and Cu2O were active components for promoting SRMe. 相似文献
77.
Li Ma Qian Wang Dr. Wai‐Lun Man Dr. Hoi‐Ki Kwong Dr. Chi‐Chiu Ko Prof. Tai‐Chu Lau 《Angewandte Chemie (International ed. in English)》2015,54(17):5246-5249
The study of manganese complexes as water‐oxidation catalysts (WOCs) is of great interest because they can serve as models for the oxygen‐evolving complex of photosystem II. In most of the reported Mn‐based WOCs, manganese exists in the oxidation states III or IV, and the catalysts generally give low turnovers, especially with one‐electron oxidants such as CeIV. Now, a different class of Mn‐based catalysts, namely manganese(V)–nitrido complexes, were explored. The complex [MnV(N)(CN)4]2− turned out to be an active homogeneous WOC using (NH4)2[Ce(NO3)6] as the terminal oxidant, with a turnover number of higher than 180 and a maximum turnover frequency of 6 min−1. The study suggests that active WOCs may be constructed based on the MnV(N) platform. 相似文献
78.
Ochratoxin A (OTA) is a toxic and potentially carcinogenic fungal toxin found in a variety of food commodities. A new sensitive method has been developed to quantify OTA in cereal products by reversed-phase liquid chromatography (LC) with mass spectrometric (MS) detection. Ochratoxin B was used as the internal standard. OTA was extracted from cereal products with acetonitrile-water, and the extract was diluted with a buffer; the diluted extract was cleaned up on an immunoaffinity column before LC/MS analysis. Two multiple-reaction monitoring transitions were used, one for quantification of OTA and one for confirmation of identity. The method was shown to be highly sensitive, with a low decision limit (CCalpha) of 0.012 microg/kg and a detection capability (CCbeta) of 0.021 microg/kg. Within-laboratory repeatability coefficient of variation values were 7.1, 3.7, and 3.1%, and the corresponding recoveries were 104, 106, and 103% for rice samples fortified with OTA at 0.05, 0.10, and 0.15 microg/kg, respectively. Method validation was performed according to the criteria of European Commission Decision 2002/657/EC. All criteria as presented in the Commission Decision were fulfilled. This method is the first fully validated method using immunoaffinity chromatography for cleanup and MS for detection in the analysis of cereals for OTA. The method was also successfully applied to cereal-derived products. The analytical results for determination of the OTA content of cereal products commercially available in Hong Kong are also reported. 相似文献
79.
80.