Reaction of a Dioxane Dichlorogermylene Complex with Compounds Containing C-H Bonds

The dioxane complex C₄H₈O₂·GeCl₂ reacts with compounds containing C-H bonds (C₆H₁₄, Me₃SiSiMe₃, C₄H₈O₂) with preferential formation of their trichlorogermyl derivatives.     

Structure of monomers of bis-(1,8-naphthylene)dichlorodisilane and bis-(1,8-naphthylene)dichlorodisiloxane

Journal of Structural Chemistry -     

Synthesis and application of organogermanium compounds

The application of organogermanium compounds (OGCs) to the creation of biologically active medicines with unique properties that possess a wide range of pharmacological actions, including the series of Panaxel drugs and Germavit mineral vitamin complex, is considered. Based on OGC, novel biologically active materials for medical technology were developed: dental flosses, retention surgical suture, bandages, and other products. The biological activity of OGC also allows to use them in perfumery and cosmetics industries. The methods for the synthesis of organogermanium compounds are described.     

Crystal structure of 1,1,3,3,8,8-hexachloro-2-oxa-1,3,8-trisilabicyclo[3.3.1]oct-5-ene

Journal of Structural Chemistry -     

Reaction of the Dioxane Complex of Dichlorogermylene with Siloxanes

The major organogermanium compounds formed by reactions of the dioxane complex of dichlorogermylene with hexamethyldisiloxane, octamethyltrisiloxane, and hexamethyltricyclotrisiloxane are bis(trimethylsiloxy)dichlorogermane, 3,3-dichloro-1,1,1,5,5,7,7,7-octamethyl-3-germa-2,4,6-trioxa-1,5,7-trisilaheptane, and a cyclic germatetrasiloxane.     

Gas-phase reactions of tetrachlorogermane with chlorothiophenes in the presence of hexachlorodisilane. Synthesis of thienylchlorogermanes

Gas-phase reactions of dichlorogermylenes formed in the GeCl₄-Si₂Cl₆ system with 2-chlorothiophene, 2,5-dichlorothiophene, 2,5-dichloro-3-methylthiophene, and 5-chloro-2-trimethylsilylthiophene is studied. It is shown that :GeCl₂ is inserted into the chlorothiophene C-Cl bond to form the derivatives containing one or two trichlorogermyl groups. In the reaction with 5-chloro-2-trimethylsilylthiophene, the insertion of :GeCl₂ into the C-Cl bond yielding 5-trichlorogermyl-2-trimethylsilylthiophene is accompanied by the exchange of the Me₃Si group with the trichlorogermyl group to form 2,5-bis(trichlorogermyl)thiophene. The reactions occurring in the course of the synthesis of thienylchlorogermanes are considered.