Longitudinal-transverse separations of deep-inelastic structure functions at low Q2 for hydrogen and deuterium

We report on a study of the longitudinal to transverse cross section ratio, R=sigmaL/sigmaT, at low values of x and Q2, as determined from inclusive inelastic electron-hydrogen and electron-deuterium scattering data from Jefferson Laboratory Hall C spanning the four-momentum transfer range 0.06相似文献   

Dark-spot formation by vector beams

Dark-spot formation is demonstrated by calculating electric-field distribution near the focus produced by focusing higher-order transverse-mode vector beams with radial and azimuthal polarizations in addition to Laguerre-Gaussian beams with linear and circular polarizations. The size of the dark spot in the radial direction varies from one beam to another, but the size in the axial direction is almost the same. The radially polarized TM02-mode beam is predicted to form a dark spot solely by an axial electric field.     

Evaluation of acoustical conditions for speech communication in working elementary school classrooms

Detailed acoustical measurements were made in 41 working elementary school classrooms near Ottawa, Canada to obtain more representative and more accurate indications of the acoustical quality of conditions for speech communication during actual teaching activities. This paper describes the room acoustics characteristics and noise environment of 27 traditional rectangular classrooms from the 41 measured rooms. The purpose of the work was to better understand how to improve speech communication between teachers and students. The study found, that on average, the students experienced: teacher speech levels of 60.4 dB A, noise levels of 49.1 dB A, and a mean speech-to-noise ratio of 11 dB A during teaching activities. The mean reverberation time in the occupied classrooms was 0.41 s, which was 10% less than in the unoccupied rooms. The reverberation time measurements were used to determine the average absorption added by each student. Detailed analyses of early and late-arriving speech sounds showed these sound levels could be predicted quite accurately and suggest improved approaches to room acoustics design.     

Numerical simulation of 2D granular particles and its analyses by means of the micropolar fluid model

Numerical simulations of two-dimensional granular flows under uniform mean shear and external body torque were performed following the setting of the authors’ previous study [10]. Convergence of the stresses with the increase of coarse-graining length is investigated. Difference R between vorticity field and spin field is controlled by the external torque and the stresses for the region R > 0 is obtained as well as those for R < 0. The symmetry of the stresses under the change of the sign of R is discussed.     

A possible interpretation of CDF dijet mass anomaly and its realization in supersymmetry

Recently, the CDF Collaboration reports an anomaly in dijet mass distribution in association with a lepton and missing energy. We discuss a possibility that the origin of the lepton and missing energy comes not from a W boson but a new boson particle, which is also responsible for the dijet mass peak. We show that such a situation can be realized in the framework of the minimal supersymmetric standard model and the dijet anomaly can be explained.     

In vivo estimation of optical properties of rat liver using single-reflectance fiber probe during ischemia and reperfusion

Optical Review - To quantify the changes in optical properties of in vivo rat liver tissue, we applied diffuse reflectance spectroscopy (DRS) system using single-reflectance fiber probe during...     

Effect of Ru crystal orientation on the adhesion characteristics of Cu for ultra-large scale integration interconnects

The adhesion of Cu on Ru substrates with different crystal orientations was evaluated. The crystal orientation of sputter deposited Ru could be changed from (1 0 0) to (0 0 1) by annealing at 650 °C for 20 min. The adhesion of Cu was evaluated by the degree of Cu agglomeration on Ru. Cu films on annealed Ru films with the (0 0 1) crystal orientation showed 28% lower RMS values and 50% lower Ru surface coverage than Cu as-deposited on Ru having the (1 0 0) crystal orientation after annealing at 550 °C for 30 min, which suggest that Cu wettability on the Ru(0 0 1) was better than that on the Ru(1 0 0) plane. The low lattice misfit of 4% between Cu(1 1 1) and Ru(0 0 1) may be the reason for this good adhesion property.     

Community responses to road traffic noise in Hanoi and Ho Chi Minh City

Vietnam is a developing country in southeast Asia, and its environment has been seriously affected by industrialization and urbanization. In large cities like Hanoi (northern Vietnam) and Ho Chi Minh City (southern Vietnam), noise emission from road traffic has been found to be a serious concern among general public. In 2005 and 2007, two large-scale socio-acoustic surveys of community response to road traffic noise were conducted to investigate human reactions to road traffic noise in these cities; the sample sizes were 1503 people in Hanoi and 1471 in Ho Chi Minh City. The noise exposure levels (L_den) were 70–83 dB in Hanoi and 75–83 dB in Ho Chi Minh City. Noise annoyance was estimated using standardized annoyance scales. For both cities, dose–response relationships were established between L_den and the percentage of highly annoyed respondents. Compared to annoyance responses of European people, Vietnamese were less annoyed by road traffic noise by about 5 dB. Hanoi respondents seemed to be more annoyed by noise than Ho Chi Minh City respondents. Conversation and sleep disturbances were not as serious as expected in either city. Furthermore, window orientation in the home was found to affect activity disturbances.     

Imprinting modulates processing of visual information in the visual wulst of chicks

Background

Results of the Women's Health Initiative Memory Study (WHIMS) raised concerns regarding the timing and formulation of hormone interventions. Conjugated equine estrogens (CEE), used as the estrogen therapy in the WHIMS trial, is a complex formulation containing multiple estrogens, including several not secreted by human ovaries, as well as other biologically active steroids. Although the full spectrum of estrogenic components present in CEE has not yet been resolved, 10 estrogens have been identified. In the present study, we sought to determine which estrogenic components, at concentrations commensurate with their plasma levels achieved following a single oral dose of 0.625 mg CEE (the dose used in the WHIMS trial) in women, are neuroprotective and whether combinations of those neuroprotective estrogens provide added benefit. Further, we sought, through computer-aided modeling analyses, to investigate the potential correlation of the molecular mechanisms that conferred estrogen neuroprotection with estrogen interactions with the estrogen receptor (ER).

Results

Cultured basal forebrain neurons were exposed to either β-amyloid_25–35 or excitotoxic glutamate with or without pretreatment with estrogens followed by neuroprotection analyses. Three indicators of neuroprotection that rely on different aspects of neuronal damage and viability, LDH release, intracellular ATP level and MTT formazan formation, were used to assess neuroprotective efficacy. Results of these analyses indicate that the estrogens, 17α-estradiol, 17β-estradiol, equilin, 17α-dihydroequilin, equilinen, 17α-dihydroequilenin, 17β-dihydroequilenin, and Δ^8,9-dehydroestrone were each significantly neuroprotective in reducing neuronal plasma membrane damage induced by glutamate excitotoxicity. Of these estrogens, 17β-estradiol and Δ^8,9-dehydroestrone were effective in protecting neurons against β-amyloid_25–35-induced intracellular ATP decline. Coadministration of two out of three neuroprotective estrogens, 17β-estradiol, equilin and Δ^8,9-dehydroestrone, exerted greater neuroprotective efficacy than individual estrogens. Computer-aided analyses to determine structure/function relationships between the estrogenic structures and their neuroprotective activity revealed that the predicted intermolecular interactions of estrogen analogues with ER correlate to their overall neuroprotective efficacy.

Conclusion

The present study provides the first documentation of the neuroprotective profile of individual estrogens contained within the complex formulation of CEE at concentrations commensurate with their plasma levels achieved after an oral administration of 0.625 mg CEE in women. Our analyses demonstrate that select estrogens within the complex formulation of CEE contribute to its neuroprotective efficacy. Moreover, our data predict that the magnitude of neuroprotection induced by individual estrogens at relatively low concentrations may be clinically undetectable and ineffective, whereas, a combination of select neuroprotective estrogens could provide an increased and clinically meaningful efficacy. More importantly, these data suggest a strategy for determining neurological efficacy and rational design and development of a composition of estrogen therapy to alleviate climacteric symptoms, promote neurological health, and prevent age-related neurodegeneration, such as AD, in postmenopausal women.