Numerical analysis of fatigue striations

A computational model was developed to numerically analyse fatigue striations. The inclined strip yield model with continuous distributions of infinitesimal dislocations was utilized to express the crack tip plasticity in this model. The fatigue crack tip blunting process was approximated by sequential activation of two slip lines under loading, and crack closure during unloading was taken into account. The plastic zone at a growing fatigue crack tip at the maximum load was independent of the crack growth up to ten cycles while the reversed plastic zone decreased in a size to one twentieth of that at the maximum load as the crack grew. The ratio of these plastic zone sizes and also the crack tip opening displacement were quite different from the simple prediction by J.R. Rice for a stationary crack. The computed striation spacings were compared with the observed ones and moderate agreement between them obtained.     

Bochner-Weitzenböck formulas and curvature actions on Riemannian manifolds

Gradients are natural first order differential operators depending on Riemannian metrics. The principal symbols of them are related to the enveloping algebra and higher Casimir elements. We give formulas in the enveloping algebra that induce not only identities for higher Casimir elements but also all Bochner-Weitzenböck formulas for gradients. As applications, we give some vanishing theorems.

     

pH-dependent column fractionation for characterization of endogenous digoxin-like immunoreactive factors in pregnant urine.

Samples of pregnant urine were treated with three diatomaceous earth columns to fractionate organic solvent-soluble components. The first column was pre-injected with the urine sample. The second and the third columns were pre-injected with sodium bicarbonate and sodium hydroxide solutions, respectively; these played an important role in capturing acidic components in the urine extract from the first column. Neutral components could be eluted out from the columns with the organic solvent, while the basic components were retained in the first column. Once strongly and weakly acidic components were captured on the alkaline columns, they were separately treated with an acidic mobile phase and recovered. The digoxin-like activities of each fraction were examined for cross-reactivity to antidigoxin antibody and inhibitory effects on dog kidney Na+, K(+)-ATPase. Both types of reactivity were found in all three fractions and decreased in the following order: strongly acidic, neutral and weakly acidic. The neutral fraction of pregnant urine showed significantly greater cross-reactivity than that of the non-pregnant urine. Following hydrolysis of the pregnant urine with beta-D-glucuronidase, the cross-reactivity of the neutral fraction increased significantly. High performance liquid chromatographic analysis showed that several components in the neutral fraction had apparently increased after the hydrolysis, showing the possible presence of unknown digoxin-like components in the pregnant urine.     

The anode surface temperature of CuCr contacts at the limit ofcurrent interruption

This paper estimates anode surface temperature at the current interruption limit by measuring the melting time of a contact material after current interruption and simulating the anode surface temperature. As a result, the minimum anode surface temperature of CuCr(50/50) contact material was about 1750 K. We also calculated the metal vapor density between electrodes with a simplified model. The calculation results showed that the critical vapor density was about 3×10²⁰ atoms/m³. This vapor density is equivalent to the averaged pressure of 8 Pa, which is close to the value of the Paschen minimum     

Stabilization against initial oxidation using surface segregation of sulfur on Fe(1 0 0)

Surface segregation process of dissolved elements on a Fe(1 0 0) surface and the initial oxidation processes of the sulfur segregated surfaces were studied in situ by AES and RHEED. The surface enrichment of sulfur has formed a c(2×2) superstructure at elevated temperatures. The Fe(1 0 0)c(2×2)-S surface was found to have stabilization effect against initial oxidation. The retardation of oxidation was most enhanced when the sulfur surface concentration reached at the saturation coverage (1/2 ML). The possible physical origins of the stabilization effect are proposed.     

Temperature dependence of the pulse-height distributions in aliphatic liquid scintillators

The pulse-height distributions for^131mXe in PPO solutions of aliphatic hydrocarbons such as n-pentane, n-hexane, n-heptane, 2,4-dimethylpentane, 2,3,4-trimethylpentane, 1-pentene, 1-hexene and 1-heptene are investigated as a function of temperature. The pulse-height distributions are found to be shifted toward higher pulse-heights with decreasing temperature. The count rates of^131mXe remain unchanged with decreasing temperature. The mechanism of the effect is also discussed.     

Prediction of human serum albumin-drug binding affinity without albumin

A new liquid chromatographic system was developed to measure protein-drug binding affinity indirectly without albumin and was evaluated using log nK values of drugs measured by a modified Hummel-Dreyer method using purified human serum albumin. The retention factors of acidic and basic drugs were measured by reversed-phase and ion-exchange liquid chromatography in sodium phosphate buffer, pH 7.40, containing 50 vol.% methanol at 37 °C. The bonded phases were pentyl, guanidino and carboxyl phases. The combined retention factors were correlated with the log nK values measured by a modified Hummel-Dreyer method because glycosylation of human serum albumin did not significantly affect log nK value. The correlation coefficients were 0.949 (n=7) for acidic drugs and 0.978 (n=5) for basic drugs. The log nK values of 26 acidic and 18 basic drugs were predicted from their retention factors measured by reversed-phase and ion-exchange liquid chromatography.