Neue Reagentien zum papierchromatographischen Nachweis von Aminosäuren, 5. Mitt.: Reaktionen des 1,2,3-Trioxo-2,3-dihydrophenalens mit primären Aminoverbindungen

Zusammenfassung Es ist gelungen, mit dem, dem Ninhydrin analog gebauten 1,2,3-Trioxo-2,3-dihydrophenalen (1), den Mechanismus der Ninhydrinreaktion aufzuklären.

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New reagents for the detection of amino acids by paper chromatography, V.: Reaction of 1.2.3-trioxo-2.3-dihydrophenalene with primary amines

The mechanism of the ninhydrin reaction has been established using 1.2.3-trioxo-2.3-dihydro-phenalen (1) as a model compound.

     

Quantitative Spurenbestimmung von Pentachlornitrobenzol, Pentachloranilin und Hexachlorbenzol in Radieschenextrakten mit Hilfe der Kombination Gas-Chromatographie/NCI-Massenspectrometrie

Ohne Zusammenfassung

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Determination of traces of pentachloronitrobenzene, pentachloroaniline and hexachlorobenzene in radish extracts by the combination GC/NCI-Mass spectrometry

     

Electron exchange chemiluminescence from a sterically stabilized cyclobutadiene-1,2-dioxetane

The rather stable 1,2-dioxetanes ($\text{2}$) and ($\text{3}$), derived from the sterically stabilized cyclobutadiene ($\text{1}$), exhibit distinct enhanced chemiluminescence behavior, namely energy transfer chemiluminescence (ETC) for ($\text{2}$) and electron exchange chemiluminescence (EEC) for ($\text{3}$).     

Synthese stereoisomerer Pinanthromboxane und Evaluation der Verbindungen als Plättchenaggregationsinhibitoren

Synthesis of Stereisomeric Pinanthromboxane Derivatives and Evaluation of the Compounds as Platelet Aggregation Inhibitors Starting from the two enantiomeric myrtenols ((?)- 1 and (+)- 1 ; cf. Scheme 1), the synthesis of twelve stereoisomeric pinanthromboxane derivatives ((+)- and (?)- 10, -11, -14, -15, -21 and -22 ) is described (cf. Schemes 1–4). Biological data from the evaluation as platelet aggregation inhibitors (cf. Table 6 and 7), thromboxane synthetase inhibitors (cf. Table 8) and from the assessment as antagonists of leukotriene E₄ induced bronchoconstriction (cf. Table 9) are presented.