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Kh. Sh. Kamoldinov K. A. Eshbakova Kh. M. Bobakulov N. D. Abdullaev 《Chemistry of Natural Compounds》2012,48(1):51-53
The new seco-iridoid glycoside raibocarpaoside was isolated from the aerial part of Fraxinus raibocarpa Rgl. (Oleaceae). The
structure 1-O-β-D-glucopyranosyl-4,6-dicarboxymethyl-8-methyl-7,8-seco-cyclopent-8-en[c]-1,9-dihydropyran was established based on spectralCharacteristics
andChemical transformations. 相似文献
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N. K. Khidyrova E. V. Van R. Kh. Shakhidoyatov Kh. M. Bobakulov N. D. Abdullaev Kh. M. Shakhidoyatov 《Chemistry of Natural Compounds》2012,48(3):358-360
Polyprenols from the aerial part of the plant Althaea officinalis were studied. It was shown that polyprenols from leaves were polyprenol homologs with 9–13 isoprene units where undecaprenol dominated. The polyprenol contents in leaves and stems and the component composition of polyprenols of this plant were determined. 相似文献
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Sodik Numonov Khayrulla Bobakulov Mukhabbat Numonova Farukh Sharopov William N. Setzer Qosimjon Khalilov 《Natural product research》2018,32(19):2325-2332
The new coumarin 1, yuganin A (7-methoxy-8-((1S,2S)-1,2,3-trihydroxy-3-methylbutyl)-2H-chromen-2-one) along with nine known coumarins, heraclenol 3′-O-β-D-glucopyranoside (2), oxypeucedanin hydrate 3′-O-β-D-glucopyranoside (3), heraclenol (4), oxypeucedanin hydrate (5), osthole (6), oxypeucedanin (7), heraclenin (8), isoimperatorin (9), imperatorin (10) and the disaccharide sucrose (11), have been isolated from the roots of Prangos pabularia, and the structures of these isolated compounds were elucidated by spectroscopic means, especially, UV, HR-ESIMS, and 1D and 2D NMR spectroscopy. Furthermore, the anti-melanogenic effect of yuganin A and its inhibitory effect on B16 cells were evaluated. Yuganin A may be useful in the treatment of hyperpigmentation and as a skin-whitening agent in the cosmetics industry. 相似文献
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Nurmirza Begmatov Jun Li Khayrulla Bobakulov Sodik Numonov 《Natural product research》2020,34(12):1772-1776
AbstractSeventeen compounds were isolated from the capitula of Coreopsis tinctoria Nutt. with various column chromatographic methods and semi-preparative HPLC. Their structures were identified by the spectroscopic data and comparison with literatures as 2′-hydroxy-4,4′-dimethoxy-chalcone; (1), isoliquiritigenin (2), eriodictyol (3), naringenin (4), maritimetin (5), butin (6), taxifolin (7), luteolin (8), 7,3′,4′-trihydroxyflavone (9), 8,3′,4′-trihydroxyflavone-7-O-β-d-glucoside (10), quercetin (11), quercetagitin-7-O-β-d-glucoside (12), quercetin-7-O-β-d-glucoside (13), 3,4-dihydroxybenzoic acid (14), caffeic acid (15), coreoside B (16), and myo-inositol (17). Compounds 1, 4, 9, 10 and 17 were isolated from C. tinctoria Nutt. for the first time. Compounds 7 and 12 possessed the highest antioxidant activity (IC50?=?64.37 and 32.86?µg/ml, respectively) among the tested compounds (IC50 value of positive control was 5.34?µg/ml). Compound 7 exhibited potent PTP1B enzymatic inhibition with an IC50 value of 7.73?μg/ml (IC50 value of positive control is 1.46?µg/ml). Furthermore, compound 5 showed strong antibacterial activity against the Gram-positive bacterium, S. aureus. 相似文献