There are large to superlarge magnesite and talc deposits occurring in Mg-rich carbonate formations distributed in the early Proterozoic Dashiqiao Formation in eastern Liaoning Province, China. The discovery of the sedimentary gypsum, isotopic geochemistry of δ18Osmow, δ13CPDB, δ34SVCDT and Sr/Ba ratio of carbonate, talc, quartz and gypsums with field investigation and sample analysis in laboratory demonstrate that the formation of magnesite and talc deposits is closely related to marine evaporates, which then underwent reworking of regional metamorphism and hydrothermal metasomatism. Metasomatic fluids originating from the paleoseawater played a controlling role in the formation of talc deposits.