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201.
A practical copper-catalyzed amination of benzoxazole with secondary amine in water has been developed. This reaction has proved to be effective to some cyclic amines, and the substituted group of nitrogen has a great impact on the amination reaction. A copper-catalyzed/ amine-induced ring opening of the benzoxazole and recyclization/oxidation mechanism was also proposed. 相似文献
202.
Jun‐Ju Xu Da‐Ke Zhao Hong‐Lian Ai Li‐Mei Zhang Shi‐Qing Xie Shu‐Hui Zi Sheng‐Chao Yang Yong Shen 《Helvetica chimica acta》2013,96(11):2155-2159
A further study of the alkaloid constituents of Aconitum forrestii led to the isolation of three new C19‐diterpenoid alkaloids, named 14‐acetoxy‐8‐O‐methylsachaconitine ( 1 ), 14‐acetoxyscaconine ( 2 ), and 8‐O‐ethylcammaconine ( 3 ). Their structures were determined by UV, IR, and MS, 1D‐ and 2D‐NMR analyses. 相似文献
203.
Three-component reaction of aromatic aldehyde, 2-naphthalenamine, and 1,2-diphenylethanone in aqueous media catalyzed by triethylbenzylammonium chloride (TEBAC) at 90 °C gave 3-aryl-3-(naphthalen-2-ylamino)-1,2-diphenylpropan-1-one derivatives. The enol form of 1,2-diphenylethanone was tentatively proposed to participate in the formation of the products. Compared with previous methods, this three-component reaction has the advantages of green solvent, good yields, and operational simplicity. 相似文献
204.
Direct condensation of carboxylic acids and alcohols with electronic, steric, and functional group variations was carried out using the environmentally benign, moisture-stable, inexpensive, and recoverable iron(III) acetylacetonate [Fe(acac)3] as catalyst (5 mol%). This iron salt efficiently catalyzed the esterification of several primary and secondary alcohols in refluxing xylene, without the need for a dehydration reagent. The chemoselectivity of the proposed protocol was demonstrated by the selective esterification of primary alcohol functionality in racemic 1-phenylethane-1,2-diol with benzoic acid. The esterification was also applicable to unmasked α -hydroxyacid, guasiaromatic, heterocyclic, and N-protected amino acids. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications® to view the free supplemental file. 相似文献
205.
Jing‐Tao Shi Chun‐Sheng Zhou Yong‐Liang Liu Zhi‐Guo Fang Rui‐Li Zhao Li‐Li Xu Ke‐Fen Yue 《无机化学与普通化学杂志》2013,639(1):187-192
Two coordination polymers (CPs), {[Zn2(BMB)(5‐AIPA)2] · 2H2O}n( 1 ) and [Zn(BMB)(5‐NIPA)]n( 2 ) {BMB = 1, 4‐bis[(2‐methyl‐imidazol‐1‐yl)methyl]benzene, 5‐AIPA = 5‐aminoisophthalic acid, 5‐NIPA = 5‐nitroisophthalic acid}, were synthesized under hydrothermal conditions. Compound 1 displays a 2D double‐layer structure, which is packed into a 3D supramolecule by interlayer hydrogen bonds and π–π stacking interactions. Compound 2 displays a threefold interpenetrating 3D network, which is composed of left‐handed helical chains and two types of meso‐helical chains along different directions. 相似文献
206.
Yanliang Ren Bo Chi Osama Melhem Ke Wei Lingling Feng Yongjian Li Xinya Han Ding Li Ying Zhang Jian Wan Xin Xu Minghui Yang 《Journal of computational chemistry》2013,34(12):1005-1012
In the present study, the electronic energy transfer pathways in trimeric and hexameric aggregation state of cyanobacteria C‐phycocyanin (C‐PC) were investigated in term of the Förster theory. The corresponding excited states and transition dipole moments of phycocyanobilins (PCBs) located into C‐PC were examined by model chemistry in gas phase at time‐dependent density functional theory (TDDFT), configuration interaction‐singles (CIS), and Zerner's intermediate neglect of differential overlap (ZINDO) levels, respectively. Then, the long‐range pigment‐protein interactions were approximately taken into account by using polarizable continuum model (PCM) at TDDFT level to estimate the influence of protein environment on the preceding calculated physical quantities. The influence of the short‐range interaction caused by aspartate residue nearby PCBs was examined as well. Only when the protonation of PCBs and its long‐ and short‐range interactions were properly taken into account, the calculated energy transfer rates (1/K) in the framework of Förster model at TDDFT/B3LYP/6‐31+G* level were in good agreement with the experimental results of C‐PC monomer and trimer. Furthermore, the present calculated results suggested that the energy transfer pathway in C‐PC monomer is predominant from β‐155 to β‐84 (1/K = 13.4 ps), however, from α‐84 of one monomer to β‐84 (1/K = 0.3–0.4 ps) in a neighbor monomer in C‐PC trimer. In C‐PC hexamer, an additional energy flow was predicted to be from β‐155 (or α‐84) in top trimer to adjacent β‐155 (or α‐84) (1/K = 0.5–2.7 ps) in bottom trimer. © 2013 Wiley Periodicals, Inc. 相似文献
207.
Lixin Xia Ke Gong Shuyan Wang Jushi Li Donghui Yang 《Journal of Dispersion Science and Technology》2013,34(11):1574-1578
Two case studies are presented that shows the effects of chemical demulsifiers used under conventional heating and in combination with microwave radiation on efficiency of demulsification and light transmittance of the water separated from the emulsions. The data shows that the chemical demulsifiers coupling with microwave radiation does a better job at demulsifying the water-in-crude-oil emulsions than when the chemical demulsifiers are used under conventional heating. The demulsification efficiency of AE-121 could reach 100% under microwave irradiation (300 W) for 50 seconds. 相似文献
208.
The synthesis, characterization and mesomorphic properties of a new type of liquid crystalline compound, the 2,5-bis(3,4,5-trialkoxyphenyl)-1,3,4-oxadiazoles, 3a-3h, are reported. These heterocyclic compounds are derived from unsaturated 1,3,4-oxadiazole as the core group, and obtained by the condensation reaction of 3,4,5-trialkoxybenzoic acid N-(3,4,5-trialkoxybenzoyl)-hydrazides and phosphorus oxychloride in toluene under reflux. All compounds were characterized by 1H and 13C NMR spectroscopy, and elemental analysis. The mesomorphic properties of these and the related compounds 1, 2 were characterized and studied by differential scanning calorimetry and polarizing optical microscopy. The formation of columnar mesophases was found to be dependent on the numbers of alkoxy sidechains. The compounds 3 exhibited hexagonal columnar (Colh) phases, however compounds 1, 2 formed crystalline phases. Compounds 3b-3e with shorter carbon chains were room temperature liquid crystals. Polar induction by nitrogen and/or oxygen atoms on the heterocyclic core ring might be responsible for the formation and better observed mesomorphic properties in this type of compound. 相似文献
209.
Dr. Ke‐Rang Wang Yue‐Qing Wang Hong‐Wei An Jin‐Chao Zhang Prof. Dr. Xiao‐Liu Li 《Chemistry (Weinheim an der Bergstrasse, Germany)》2013,19(8):2903-2909
A new triazatruxene‐based fluorescent glycocluster has been designed, synthesized, and fully characterized by NMR spectroscopy and mass spectrometry. Furthermore, its specific and selective binding properties with concanavalin A (Con A) have been investigated by fluorescence spectroscopy, circular dichroism (CD) spectroscopy, and turbidity assay. The obtained results showed that the multivalent mannose‐modified triazatruxene exhibited specific binding with Con A, but no binding to peanut agglutinin (PNA) lectin or bovine serum albumin (BSA), corresponding to a two‐orders‐of‐magnitude higher affinity than that of monovalent mannose ligands. Most interestingly, a fluorescence enhancement of the triazatruxene‐based glycocluster was observed upon binding with Con A because of hydrophobic interactions involving sites close to the triazatruxene moiety. Furthermore, the inhibitory ability of the triazatruxene‐based glycocluster against ORN178‐ induced haemagglutination has been investigated by haemagglutination inhibition assay. The results indicated selective binding with ORN178. 相似文献
210.
Liang Cui Yanling Song Guoliang Ke Zhichao Guan Huimin Zhang Ya Lin Yishun Huang Dr. Zhi Zhu Prof. Chaoyong James Yang 《Chemistry (Weinheim an der Bergstrasse, Germany)》2013,19(32):10442-10451
Recently, the binding ability of DNA on GO and resulting nuclease resistance have attracted increasing attention, leading to new applications both in vivo and in vitro. In vivo, nucleic acids absorbed on GO can be effectively protected from enzymatic degradation and biological interference in complicated samples, making it useful for targeted delivery, gene regulation, intracellular detection and imaging with high uptake efficiencies, high intracellular stability, and very low toxicity. In vitro, the adsorption of ssDNA on GO surface and desorption of dsDNA or well‐folded ssDNA from GO surface result in the protection and deprotection of DNA from nucleic digestion, respectively, which has led to target‐triggered cyclic enzymatic amplification methods (CEAM) for amplified detection of analytes with sensitivity 2–3 orders of magnitude higher than that of 1:1 binding strategies. This Concept article explores some of the latest developments in this field. 相似文献