Electro-optic light modulation with holographic gratings stored in a Cu-diffused LiNbO3 plate

Investigations have been made on the electro-optic modulation of a laser beam using Bragg reflection from holographic gratings stored in a Cu-diffused LiNbO₃ plate. A new device configuration is proposed which makes it possible to use the holographic recording characteristics of LiNbO₃ more effectively than previous other devices. A modulation of about 50% with a 45° deflection angle was obtained at an applied voltage of 500 V.     

Cu-diffused layers in LiNbO3 for reversible holographic storage

Some holographic recording characteristics of Cu-diffused layers fabricated in Rh-doped LiNbO₃ have been examined in comparison with those fabricated in undoped lithium niobate.The diffusion layers, whose thickness depends on the diffusion temperature, are found to be enormously susceptible to optically-induced refractive index changes and to be able to attain a high diffraction efficiency. A distinguished difference is found between the persistence of holograms stored in Rh-doped and undoped LiNbO₃.     

Dual chirality control of palladium(II) complexes bearing tropos biphenyl diamine ligands

Axial and center chirality of Pd complexes with tropos biphenyl secondary diamine ligands is shown to be controlled by chiral amide (R)-DABNTf, which can efficiently discriminate between two enantiomeric Pd complexes.     

Effects of oxygen-deficiencies on the recording sensitivity of holograms in Rh-doped LiNbO3

It was found that the generation of oxygen-deficiencies in Rh-doped LiNbO₃ enormously improved the optical sensitivity for holographic recording. Optical erasing and thermal decaying of holograms exhibited a two-step decay behavior, which suggested the existence of two kinds of trapping levels relevant to the optical damage.     

Highly enantioselective spiro cyclization of 1,6-enynes catalyzed by cationic skewphos rhodium(I) complex

A cationic rhodium(I) complex having a skewphos ligand is shown to be a highly enantioselective catalyst for asymmetric carbocyclization of 1,6-enynes with tri-substituted olefins to control quaternary stereogenic centers of spiro-rings.     

Development of a highly selective fluorescence probe for hydrogen sulfide

Hydrogen sulfide (H(2)S) has recently been identified as a biological response modifier. Here, we report the design and synthesis of a novel fluorescence probe for H(2)S, HSip-1, utilizing azamacrocyclic copper(II) ion complex chemistry to control the fluorescence. HSip-1 showed high selectivity and high sensitivity for H(2)S, and its potential for biological applications was confirmed by employing it for fluorescence imaging of H(2)S in live cells.     

Synthesis of Sugar and Nucleoside Analogs and Evaluation of Their Anticancer and Analgesic Potentials

Chemical modification of sugars and nucleosides has a long history of producing compounds with improved selectivity and efficacy. In this study, several modified sugars (2–3) and ribonucleoside analogs (4–8) have been synthesized from α-d-glucose in a total of 21 steps. The compounds were tested for peripheral anti-nociceptive characteristics in the acetic acid-induced writhing assay in mice, where compounds 2, 7, and 8 showed a significant reduction in the number of writhes by 56%, 62%, and 63%, respectively. The compounds were also tested for their cytotoxic potential against human HeLa cell line via trypan blue dye exclusion test followed by cell counting kit-8 (CCK-8) assay. Compound 6 demonstrated significant cytotoxic activity with an IC₅₀ value of 54 µg/mL. Molecular docking simulations revealed that compounds 2, 7, and 8 had a comparable binding affinity to cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzymes. Additionally, the bridged nucleoside analogs 7 and 8 potently inhibited adenosine kinase enzyme as well, which indicates an alternate mechanistic pathway behind their anti-nociceptive action. Cytotoxic compound 6 demonstrated strong docking with cancer drug targets human cytidine deaminase, proto-oncogene tyrosine-protein kinase Src, human thymidine kinase 1, human thymidylate synthase, and human adenosine deaminase 2. This is the first ever reporting of the synthesis and analgesic property of compound 8 and the cytotoxic potential of compound 6.     

The effect of Ag addition on electrical properties of the thermoelectric compound Ca3Co4O9

Ca₃Co₄O₉/Ag composites incorporating different amounts of Ag were synthesized by solid-state reaction. Scanning electron microscopy revealed Ag particles dispersed among and combined with Ca₃Co₄O₉ grains several times larger in size. The electrical resistivity (ρ) of the composites is favorably lower than that of Ca₃Co₄O₉ alone and decreases with increasing Ag content. It can thus be inferred that the highly conductive Ag particles between the oxide grains contribute to the reduction of ρ. Although minimal in smaller amounts, the addition of Ag also seems to have a negative impact on the Seebeck coefficient (S) of the composites due to its poor S. Since the reduction of ρ is more significant than the degradation of S, the power factor is found to be improved by the addition of 10 wt% Ag.