The millimeter-wave spectrum of chlorine nitrate (ClONO2): The ν6 vibrational state

The pure rotational spectrum of chlorine nitrate in its v₆ = 1 excited vibrational state has been studied. A total of 2901 lines, with K_a extending to 33 in the ³⁵Cl isotopologue and 30 in the ³⁷Cl isotopologue, respectively, have been recorded and assigned. This analysis, along with our recently reported study of the ν₅/ν₆ν₉ dyad and the improved energy levels of ν₉ reported in this paper, should make possible accurate simulation of the corresponding ν₆ band and its complex hot band structure near 435 cm⁻¹.     

The191Os/191mIr generator for clinical use

An evaluation of adsorbents for potential use in the¹⁹¹Os/^191mIr medical radionuclide generator was performed. The adsorbents included 39 inorganic materials broadly classified as oxides, antimonates, ferro-ferricyanides, phosphates, sulfides, and miscellaneous including activated carbon and the organic anion-exchanger AGMP-1. The uptake of¹⁹¹Os in oxidation states (VI) [potassium tetrachloroosmate], (IV) [potassium hexachloroosmate] and (III) [potassium hexathiocyanatoosmate] was measured. Adsorbents having a high¹⁹¹Os uptake were evaluated for^191mIr elution yield using three physiologically compatible eluents. Only activated carbon and AGMP-1 adsorbents showed significant^191mIr elution yields under the test conditions (10% and 37%, respectively). The results of these studies suggest that activated carbon may be a promising adsorbent for development of a new¹⁹¹Os/^191mIr medical radionuclide generator. Activated carbon is a good candidate for further development since it is inert to the chemical and radiation effects which may effect an organic based ion exchange material such as AGMP-1.Research sponsored by the Office of Health and Environmental Research, U.S. Department of Energy under contract DE-AC05-840R21400 with Martin Marietta Energy Systems, Inc.     

Dependence of relativistic backward wave oscillator properties oneffective beam gamma

The operation of a backward wave oscillator (BWO) is shown to be critically dependent on the energy of the slow space-charge wave of the electron beam. Experimental work parameterizing the dependence of microwave frequency on effective beam energy, γ_beam, reveals that through an understanding of electron-beam dynamics, a BWO could be systematically tuned through a desired frequency range while maintaining a high power of a few hundred megawatts and narrow frequency bandwidth, which was 400 MHz. Through variation of γ_beam, 1.2 to 1.5 for the experiment, the lack of scaling of peak microwave power with the kinetic energy of the electron beam for γ_beam >1.32 was observed. This effect was previously found in numerical simulation. In order to explain this effect, the relationship of the beam current to the space-charge-limiting current for increasing γ_beam is examined. Dramatic evidence of pulse shortening, a phenomenon known to relativistic oscillators, was also seen     

Tripyrrolidinophosphoric acid triamide as an activator in samarium diiodide reductions

The electrochemical and spectrophotometric characterization of the complex formed from samarium diiodide and 4 equiv of tripyrrolidinophosphoric acid triamide (TPPA) is presented. Kinetic studies indicate that the SmI(2)/TPPA complex possesses reactivity greater than the complex formed between samarium diiodide and 4 equiv of HMPA. Examples of the use of SmI(2)/TPPA in synthesis are presented.     

Non-nucleoside building blocks for copper-assisted and copper-free click chemistry for the efficient synthesis of RNA conjugates

Novel non-nucleoside alkyne monomers compatible with oligonucleotide synthesis were designed, synthesized, and efficiently incorporated into RNA and RNA analogues during solid-phase synthesis. These modifications allowed site-specific conjugation of ligands to the RNA oligonucleotides through copper-assisted (CuAAC) and copper-free strain-promoted azide-alkyne cycloaddition (SPAAC) reactions. The SPAAC click reactions of cyclooctyne-oligonucleotides with various classes of azido-functionalized ligands in solution phase and on solid phase were efficient and quantitative and occurred under mild reaction conditions. The SPAAC reaction provides a method for the synthesis of oligonucleotide-ligand conjugates uncontaminated with copper ions.     

Determination of multiresidue pesticides in green tea by using a modified QuEChERS extraction and ion-trap gas chromatography/mass spectrometry

The pesticide residues in exported and imported tea products must not exceed the maximum residue limits (MRLs) regulated by the import countries. Tea is a complex matrix that obfuscates the determination of pesticide residues. Many available methods for multiresidue pesticide analysis of tea are time-consuming and require many cleanup steps. The objective of this study was to develop a simple multiresidue method by using a modified quick, easy, cheap, effective, rugged, and safe (QuEChERS) extraction and ion-trap GC/MS/MS, which can identify, confirm, and quantify pesticides in complex matrixes. A tea product was homogenized with water, and the pesticides were extracted with acetonitrile containing 1% acetic acid. The extract was subjected to centrifugation, initial cleanup with dispersive SPE (dSPE), solvent exchange, and final cleanup with dSPE. Diethyl-d10-parathion and triphenyl phosphate were used as the internal standard and surrogate, respectively. The final extract was injected into an ITQ 700 gas chromatograph/mass spectrometer. Quantitation of individual pesticides was based on matrix-matched calibration curves with a correlation coefficient of > 0.9930 for the 22 pesticides selected for the study. The recoveries of the 22 pesticides ranged from 78 to 115%, except those for diazinon (130%) and malathion (122%), with an average RSD of 8.7%. The LOD values of all of the pesticides, except for terbufos, were below the MRLs set by the European Union and Japan.     

Autoresonant excitation of antiproton plasmas

We demonstrate controllable excitation of the center-of-mass longitudinal motion of a thermal antiproton plasma using a swept-frequency autoresonant drive. When the plasma is cold, dense, and highly collective in nature, we observe that the entire system behaves as a single-particle nonlinear oscillator, as predicted by a recent theory. In contrast, only a fraction of the antiprotons in a warm plasma can be similarly excited. Antihydrogen was produced and trapped by using this technique to drive antiprotons into a positron plasma, thereby initiating atomic recombination.     

High sensitivity and high selectivity terahertz biomedical imaging

We demonstrate two distinct emerging terahertz (THz) biomedical imaging techniques.One is based on the use of a new single frequency THz quantum cascade laser and the other is based on broadband THz time domain spectrocopy.The first method is employed to derive a metastasis lung tissue imaging at 3.7 THz with clear contrast between cancerous and healthy areas.The second approach is used to study an osseous tissue under several imaging modalities and achieve full THz spectroscopic imaging based on the freque...     

Atomic Absorption Calibration Curves Using a Sophisticated Desk Calculation System

With the advance of atomic absorption spectroscopy and the degree of automation obtained in instruments today, the preparation of calibration curves and the ensuing calculations are, apart from the sample preparation in certain cases, the most time consuming part of an atomic absorption analysis. It is usually at this stage that errors are introduced, either as a result of miscalculation or of the operator's personal bias. Both these factors can be overcome by using a programmable desk calculating system, and would be of special importance to laboratories where routine analyses are conducted. It is also of use in cases where elements are only determined periodically.     

Super-measures and finitely defined topological measures

We introduce a class of set-functions on the set of natural numbers, which are called super-measures. Super-measures are then utilized to characterize a certain class of topological measures (previously called quasi-measures, see below) which arises naturally. The members of this class of topological measures are called finitely defined, and are shown to be dense in the set of all topological measures. This revised version was published online in June 2006 with corrections to the Cover Date.