磷锑钼抗光度法测定分子筛中的磷

研究建立了以磷（V）－洒石酸锑钾－钼酸铵－抗坏血酸显色体系测定分子筛中磷含量的新方法，提出了测定磷的最佳条件，在0.22mol·L^-1硫酸介质中，该显色体系最大吸收波长位于704nm，该波长处表观ε＝7.82×10^3L·mol^-1·cm^-1，磷（V）含量在0－0.90μg/mL浓度范围内遵守比耳定律。本法用于分子筛中磷含量的测定，获得了令人满意的结果。     

柠檬酸盐法制备(Na0.5 Bi0.5)1-xBaxTiO3压电陶瓷的极化特性研究

采用柠檬酸盐法合成了具有单一钙钛矿结构的(Nao5Bio5)1-xBaxTiO3(x=0,x=0.04)超细粉料,并研究了陶瓷样品的极化特性、压电性能和铁电性能.研究结果表明,柠檬酸与金属离子的摩尔比(C/M)控制在1.2～1.6、前驱体液的pH值控制在7～9范围内可以得到均匀透明的溶胶和凝胶,凝胶在600℃下热处理1h后可形成单一钙钛矿结构的超细粉料.XRD研究结果表明,x=0和x=0.04时陶瓷样品均为三方钙钛矿结构.极化电压和极化温度对陶瓷样品的压电性能有很大影响,而极化时间对压电性能的影响则不显著.Ba2+的固溶改善了陶瓷样品的铁电性能,有利于材料极化性能和压电性能的提高.与常规固相法制备的同种组成样品相比,柠檬酸盐法制备的(Nao5Bi0.5)1-xBaxTiO3(x=0,x=0.04)陶瓷具有较好的压电性能.     

Improvement in the Physical Function and Quality of Life through Exercise and Physical Activity Intervention Using a Smartphone after Allogeneic Hematopoietic Cell Transplantation: A Case Report

Purpose: Physical activity (PA) interventions positively affect the physical function (PF) in patients with advanced cancer. However, patients must remain motivated during the intervention. We report a case wherein a smartphone application for PA intervention was useful in motivating the patient to improve adherence. Methods: A 40-year-old woman underwent an allogeneic hematopoietic cell transplantation (allo-HCT) for an advanced extranodal natural killer/T-cell lymphoma. On day 6, she developed the posterior reversible encephalopathy syndrome. She was managed in the intensive care unit for 3 days, and her PF declined markedly. We initiated a smartphone-based PA intervention from day 35. She was instructed to maintain a PA diary for self-monitoring of the daily steps and to set a new step-count goal every week. Results: The PA and PF improved within a short period thereafter. However, she developed severe acute graft-versus-host disease and was administered with high-dose systemic corticosteroids from day 49. The PA, PF, and quality of life (QOL) decreased again. The intervention was continued for 5 months with a high adherence. The PA, PF, and QOL improved gradually. She resumed independent activities of daily living and was discharged on day 202. Conclusion: Smartphone-based PA intervention may be effective against post-allo-HCT physical dysfunction.     

2，5-二烷基-1，4-苯二酚类衍生物的新合成方法

研究了合成2，5-二烷基-1，4-苯二酚衍生物的新方法，该方法是以2-取代烷 基1，4-环已二酮为原料，在LiCl催化下，与各种醛缩合反应就得2，5-二烷基-1， 4-苯二酚衍生物，是一种由非芳香环化合物合成2，5-二烷基-1，4-苯二酚衍生物 的新方法。应用该方法简便地合成了天然化合物η-生育酚。     

New Diarylheptanoid from the Barks of Alnus japonica Steudel

A new diarylheptanoid glycoside, 1,7-bis-（3,4-dihydroxyphenyl）-5-hydroxyheptane- 3-O-β-D-xylopyranoside （1）, together with nine known diarylheptanoids （2-10） were isolated from the fresh bark of Alnus japonica which is a species of the genus Alnus species, growing throughout Korea.     

Theory of the nucleation of protein macromolecular ions

Protein molecules are amphoteric and exist in aqueous solution as macromolecular ions that carry a charge which depends upon temperature and pH. Despite the repulsive Coulomb forces acting between them, protein macromolecular ions can form crystals in pH buffered solutions of strong electrolytes. It is proposed that the first step in the mechanism of crystallization is the formation of crystal nuclei made from partially discharged macromolecular ions that have exchanged H⁺ with the buffer. We suggest that the strength of the bare Coulomb repulsive force is weakened by the Debye-Hückel plasma screening provided by the inert electrolyte. This screening causes the rate of nucleus formation to increase with increasing ionic strength. Extending classic nucleation theory to account for these various charge effects, the results are applied to the case of lysozyme and a calculation is made of the dependence of the steady state nucleation rate upon temperature, pH, ionic strength, and protein supersaturation. It is found that the nucleation rate increases with increasing temperature and increasing ionic strength. Under condition of fixed temperature, supersaturation, and inionic strength, the nucleation rate has local maxima at low pH, where individual lysozyme macro ions are highly charged, and at pH ? 11, where they have zero average net charge. At both pH values, the nucleus that determines the rate has minimum size. In contrast to standard nucleation theory, which ignores charge, it is found that the size of the nucleus that controls the rate is different from the size of the nucleus that has the lowest concentration. All other conditions being the same, it is predicted that lysozyme crystals should nucleate most rapidly near pH = 2 and near pH = 11.     

Production parameters of the therapeutic 105 Rh radionuclide using medium energy cyclotron

Production cross-sections of the therapeutic ¹⁰⁵Rh radionuclide from proton-induced reactions on natural palladium target were measured using stacked-foil activation technique combined with high resolution ??-ray spectrometry at the MC50 cyclotron of the Korea Institute of Radiological and Medical Sciences. Note that cyclotron production of the ¹⁰⁵Rh radionuclide from natural palladium target was measured here for the first time. Results are compared with the theoretical values obtained using the model codes TALYS and ALICE-IPPE. Thick target integral yields for the investigated ¹⁰⁵Rh radionuclide were deduced from the threshold energy to 40?MeV. Measured data of the ¹⁰⁵Rh radionuclide are important because of its potential applications in nuclear medicine and/or therapeutic purposes. Optimal production circumstances for the therapeutic ¹⁰⁵Rh radionuclide using a cyclotron are discussed elaborately.     

An armature structure for 3D shapes

We present a novel armature structure for 3D articulated shapes, called SBall short for skeletal balls, which includes two parts： a one-dimensional skeleton and incident balls. Our algorithm mainly focuses on constructing the armature structure. This structure is based on an approximation skeleton which is homotopy equivalent to the shape. Each ball in the structure connects a skeletal joint and an interior region of the shape. The boundary vertices on the shape surface are attached onto the SBall using the power diagram of the ball set. A bilateral O~tering algorithm and a variational segmentation algorithm are proposed to enhance the quality of SBall. Finally, applications of this structure are discussed.     

一种DNA染料结合聚合酶链反应检测鉴别植物病原细菌死活细胞

建立了一种将DNA染料(EMA)结合PCR的新分析方法, 用于有效检测区分植物病原细菌死活细胞. 结果表明, 当用2.0 mg/L或更高浓度的EMA渗透处理含有106 cfu/mL的死细胞菌悬液后再曝光处理10 min, 其PCR结果呈阴性, 而未经过EMA渗透处理的对应样品PCR结果呈阳性; EMA渗透处理含有适当数量病菌活细胞的种子浸泡液后, 更有助于特异性检测混合体系中靶标菌活细胞. 分析认为, 该方法避免了传统PCR无法区分细菌死活细胞的弊端, 是一种快速、灵敏且能有效鉴别病原细菌死活细胞的新方法.     

Analysis of piezoelectric ceramic multilayer actuators based on an electro-mechanical coupled meshless method

This paper presents an efficient meshless method for analyzing cracked piezoelectric structures subjected to mechanical and electrical loading. In this method, an element free Galerkin (EFG) formulation, an enriched basic function and some special shape functions that contain discontinuous derivatives are employed. Based on the moving least squares (MLS) interpolation approach, the EFG method is one of the promising methods for dealing with problems involving progressive crack growth. Since the method is meshless and no element connectivity data are needed, the burdensome remeshing procedure required in the conventional finite element method (FEM) is avoided. The numerical results show that the proposed method can yield an accurate near-tip stress field in an infinite piezoelectric plate containing an interior hole. In another example studying a ceramic multilayer actuator, the proposed model was found to be accurate in the simulation of stress and electric field concentrations arround the abrupt end of an internal electrode. The project supported by the National Natural Science Foundation of China (10025209, 10132010, and 90208002), and the Research Grants Council of the Hong Kong Special Administrative Region, China (HKU 7203/03E). The English text was polished by Yunming Chen.