Synthesis of proline-modified analogues of the neuroprotective agent glycyl-l-prolyl-glutamic acid (GPE)

The synthesis of ten proline-modified analogues of the neuroprotective tripeptide GPE is described. Five of the analogues incorporate a proline residue with a hydrophobic group at C-2 and two further analogues have this side chain locked into a spirolactam ring system. The pyrrolidine ring was also modified by replacing the γ-CH₂ group with sulfur and/or incorporation of two methyl groups at C-5.     

On the Dimension of Posets with Cover Graphs of Treewidth 2

In 1977, Trotter and Moore proved that a poset has dimension at most 3 whenever its cover graph is a forest, or equivalently, has treewidth at most 1. On the other hand, a well-known construction of Kelly shows that there are posets of arbitrarily large dimension whose cover graphs have treewidth 3. In this paper we focus on the boundary case of treewidth 2. It was recently shown that the dimension is bounded if the cover graph is outerplanar (Felsner, Trotter, and Wiechert) or if it has pathwidth 2 (Biró, Keller, and Young). This can be interpreted as evidence that the dimension should be bounded more generally when the cover graph has treewidth 2. We show that it is indeed the case: Every such poset has dimension at most 1276.     

Semi-wet growth and characterization of multi-functional nano-engineered mixed metal oxides for industrial application

This review paper covers the low temperature wet growth of nano-engineered particles of ZnO-based mixed metal oxides, their growth mechanism, and characterization using X-ray diffraction, SEM, TEM and IR, UV–visible, and XPS spectral techniques. Main focus of this article is centered on low temperature semi-wet methods of synthesis that are suitable for large scale production of zinc oxide-based systems mixed with iron oxide, copper oxide, nickel oxide and cobalt oxide. These mixed metal oxides have broad industrial applications as catalyst, semiconductors, adsorbents, superconductors, electro-ceramics, and antifungal agents in addition to extensive applications in medicines. This paper discusses the low-cost and environment friendly synthesis of these mixed metal oxides, measurement of properties and applicability of these materials systems.