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181.
G. Tiana M.H. Jensen K. Sneppen 《The European Physical Journal B - Condensed Matter and Complex Systems》2002,29(1):135-140
A feedback mechanism that involves the proteins p53 and mdm2, induces cell death as a controlled response to severe DNA damage.
A minimal model for this mechanism demonstrates that the response may be dynamic and connected with the time needed to translate
the mdm2 protein. The response takes place if the dissociation constant k between p53 and mdm2 varies from its normal value. Although it is widely believed that it is an increase in k that triggers the response, we show that the experimental behaviour is better described by a decrease in the dissociation
constant. The response is quite robust upon changes in the parameters of the system, as required by any control mechanism,
except for few weak points, which could be connected with the onset of cancer.
Received 8 May 2002 / Received in final form 9 July 2002 Published online 17 September 2002 相似文献
182.
Z. V. Golubenko A. S. Kamzin L. P. Ol’khovik M. M. Khvorov Z. I. Sizova V. P. Shabatin 《Physics of the Solid State》2002,44(9):1698-1702
Magnetization and remagnetization processes in a close-packed nanodispersed barium hexaferrite powder sample in the magnetically stable state were analyzed. Reversibility effects were discussed in terms of interparticle interaction. Judging from the magnetization curve and the parameters characterizing remagnetization irreversibility, the sample under study is a model system of small Stoner-Wohlfarth particles. 相似文献
183.
James K. Freericks Elliott H. Lieb Daniel Ueltschi 《Communications in Mathematical Physics》2002,227(2):243-279
The Falicov–Kimball model is a simple quantum lattice model that describes light and heavy electrons interacting with an
on-site repulsion; alternatively, it is a model of itinerant electrons and fixed nuclei. It can be seen as a simplification
of the Hubbard model; by neglecting the kinetic (hopping) energy of the spin up particles, one gets the Falicov–Kimball model.
We show that away from half-filling, i.e. if the sum of the densities of both kinds of particles differs from 1, the particles
segregate at zero temperature and for large enough repulsion. In the language of the Hubbard model, this means creating two
regions with a positive and a negative magnetization.
Our key mathematical results are lower and upper bounds for the sum of the lowest eigenvalues of the discrete Laplace operator
in an arbitrary domain, with Dirichlet boundary conditions. The lower bound consists of a bulk term, independent of the shape
of the domain, and of a term proportional to the boundary. Therefore, one lowers the kinetic energy of the itinerant particles
by choosing a domain with a small boundary. For the Falicov- Kimball model, this corresponds to having a single “compact”
domain that has no heavy particles.
Received: 21 June 2001 / Accepted: 4 January 2002 相似文献
184.
We prove that the diffusion semigroups generated by the second order differential ultraspherical (Gegenbauer) operator are pseudomeasure operators. 相似文献
185.
We consider Markov processes built from pasting together pieces of strong Markov processes which are killed at a position
dependent rate and connected via a transition kernel. We give necessary and sufficient conditions for local absolute continuity
of probability laws for such processes on a suitable path space and derive an explicit formula for the corresponding likelihood
ratio process. The main tool is the consideration of the process between successive jumps – what we call ‘elementary experiments’
– and criteria for absolute continuity of laws of the process there. We apply our results to systems of branching diffusions
with interactions and immigrations.
This revised version was published online in June 2006 with corrections to the Cover Date. 相似文献
186.
187.
S. V. Prants 《JETP Letters》2002,75(12):651-658
A semiclassical study is carried out of the nonlinear interaction dynamics between two-level atoms and a standing-wave field in a high-finesse cavity. As a result of atomic movement or wave amplitude modulation, a dynamic local instability occurs in a strongly coupled atom-field system. The appearance of dynamical Hamiltonian chaos, fractals, and Lévy flights is demonstrated for the models of two experimental devices: a (micro)maser with thermal Rydberg atoms and a microlaser with cold atoms. Numerical simulation showed that the manifestations of classical chaos, atomic fractals, and flights can be observed in the appropriate real experiments. Attention is drawn to the prospects provided by work on the atom-field systems in the coupling-modulated high-finesse cavities for further investigation of the quantum-classical correspondence, quantum chaos, and decoherence. 相似文献
188.
Summary In virtually all neutron activation analysis laboratories, researchers are given film badges known as thermoluminescence dosimeters
(TLD's) that are monitored on a monthly basis. Sometimes additional pocket dosimeters are worn to get a daily reading of exposure,
while in other instances ring badges are worn to assess beta doses. However, more than often little consideration is given
to beta-exposure rates that arise from the plethora of radionuclides produced in the many types of samples irradiated. A common
mistake is to assess gamma-exposures of activated samples that rely on the use of a beta-shield on the survey meter. Our experimental
results have shown that there are many high energy beta-particles from neutron activated samples that can easily penetrate
the beta-shield and thus give an underestimation of the total beta-exposure. 相似文献
189.
The method described in this paper allows an investigator to determine the intrinsic stress of a polymer layer in a way that
does not result in damage to devices or test structures. The method requires that a small area of the polymer be released
from the substrate to form a diaphragm. The diaphragm is stimulated with acoustic white noise and the diaphragm movement is
monitored with a laser vibrometer. The first few resonance frequencies of the diaphragm are obtained using a laser vibrometer
and then those frequencies are used to calculate the membrane intrinsic bi-axial tension. 相似文献
190.