The numerical integration of relative equilibrium solutions. The nonlinear Schrodinger equation

We analyse different error propagation mechanisms for conservativeand nonconservative time-integrators of nonlinear Schrödingerequations. We use a geometric approach based on interpretingwaves as relative equilibria.     

Low-level laser therapy improves skeletal muscle performance, decreases skeletal muscle damage and modulates mRNA expression of COX-1 and COX-2 in a dose-dependent manner

We tested if modulation in mRNA expression of cyclooxygenase isoforms (COX-1 and COX-2) can be related to protective effects of phototherapy in skeletal muscle. Thirty male Wistar rats were divided into five groups receiving either one of four laser doses (0.1, 0.3, 1.0 and 3.0 J) or a no-treatment control group. Laser irradiation (904 nm, 15 mW average power) was performed immediately before the first contraction for treated groups. Electrical stimulation was used to induce six tetanic tibial anterior muscle contractions. Immediately after sixth contraction, blood samples were collected to evaluate creatine kinase activity and muscles were dissected and frozen in liquid nitrogen to evaluate mRNA expression of COX-1 and COX-2. The 1.0 and 3.0 J groups showed significant enhancement (P < 0.01) in total work performed in six tetanic contractions compared with control group. All laser groups, except the 3.0 J group, presented significantly lower post-exercise CK activity than control group. Additionally, 1.0 J group showed increased COX-1 and decreased COX-2 mRNA expression compared with control group and 0.1, 0.3 and 3.0 J laser groups (P < 0.01). We conclude that pre-exercise infrared laser irradiation with dose of 1.0 J enhances skeletal muscle performance and decreases post-exercise skeletal muscle damage and inflammation.     

Determination of Quinine and Doxycycline in Rat Plasma by LC�CMS�CMS: Application to a Pharmacokinetic Study

A fast, sensitive, and specific LC?CMS?CMS method for determination of quinine (QN) and doxycycline (DOX) in rat plasma has been developed and validated. QN, DOX, and cimetidine (internal standard, IS) were extracted from the plasma by protein precipitation. The compounds were separated on a C₁₈ column with methanol?C0.1% aqueous formic acid 70:30 (v/v) as mobile phase at a flow rate of 0.5 mL min^?1 (split 1:3). Detection was by positive electrospray ionization (ESI+) in multiple reaction monitoring (MRM) mode, monitoring the transitions 325.0 ?? 307.0, 445.0 ?? 428.1, and 252.8 ?? 159.0, for QN, DOX, and IS, respectively. The analysis was carried out in 2.0 min and the method was linear in the plasma concentration range 5?C5,000 ng mL^?1. The mean extraction recoveries for QN, DOX, and IS from plasma were 89.4, 90.5, and 86.3%, respectively. The method was validated for linearity, precision, accuracy, specificity, and stability; the results obtained were within the acceptable range. The proposed method was successfully applied to the determination of QN and DOX in rat plasma samples to support pharmacokinetic studies.     

The dynamic behavior of a cantilever beam coupled to a non-ideal unbalanced motor through numerical and experimental analysis

An excitation force that is not influenced by the system state is said to be an ideal energy source. In real situations, a direct and feedback coupling between the excitation source and the system must always exist at a certain level. This manifestation of the law of conservation of energy is known as the Sommerfeld effect. In the case of obtaining a mathematical model for such a system, additional equations are usually necessary to describe the vibration sources with limited power and its coupling with the mechanical system. In this work, a cantilever beam and a non-ideal DC motor fixed to its free end are analyzed. The motor has an unbalanced mass that provides excitation to the system which is proportional to the current applied to the motor. During the coast up operation of the motor, if the drive power is increased slowly, making the excitation frequency pass through the first natural frequency of the beam, the DC motor speed will remain the same until it suddenly jumps to a much higher value (simultaneously its amplitude jumps to a much lower value) upon exceeding a critical input power. It was found that the Sommerfeld effect depends on some system parameters and the motor operational procedures. These parameters are explored to avoid the resonance capture in the Sommerfeld effect. Numerical simulations and experimental tests are used to help gather insight of this dynamic behavior.     

New methodology for obtaining CdTe quantum dots by using ultrasound

Luminescent CdTe quantum dots (Qdots) have been produced at few minutes by using a new, simple and fast methodology in an aqueous medium by using ultrasound irradiation to accelerate the process of tellurium reduction. The structural and optical properties were characterized by TEM, XRD, absorption and fluorescence spectrocopy. The produced Qdots are in a strong quantum confinement regime and have only one fluorescence band. Moreover, the nanoparticles seem to be monodispersed, which is in accordance with the fluorescence results. We have developed a simple route for preparing monodispersed CdTe Qdots in an aqueous media. The use of ultrasound allows the morphology to be better controlled and the surfaces defects of Qdots to be reduced.     

On the number of cells for flexural vibration suppression in periodic beams

Meccanica - Vibration suppression is an important topic for many engineering applications. There are different techniques, typically involving passive and active controllers. However, it can...     

A WIN-WIN approach to multiple objective linear programming problems

Interactive decision making arose as a means to overcome the uncertainty concerning the decision maker's (DM) value function. So far the search is confined to nondominated alternatives, which assumes that a win–lose strategy is adopted. The purpose of this paper is to suggest a complementary interactive algorithm that uses an interior point method to solve multiple objective linear programming problems. As the algorithm proceeds, the DM has access to intermediate solutions. The sequence of intermediate solutions has a very interesting characteristic: all of the criteria are improved, that is, a solution Open image in new window , that follows another solution Open image in new window , has the values of all objectives greater than those of Open image in new window . This WIN-WIN feature allows the DM to reach a nondominated solution without making any trade-off among the objective functions. However, there is no impediment in proceeding with traditional multiobjective methods.     

Analysis of the interface configuration and flow characteristics in tanks in a multiphase liquid–gas system using numerical simulation

A multiphase study was conducted using a turbulence model of large eddy simulation to investigate the interaction between the gaseous phase and the interface and its respective behaviour until the liquid phase movement was established, first in the near interface, as well as the presence of turbulent structures in the study of transport between phases. The results are shown for three surface configurations: a surface with waves in which the Reynolds number and friction velocity of the gaseous phase are, respectively, 210 and 0.25 m/s; a surface with small undulations, 86 and 0.10 m/s; and a flat surface, 43 and 0.05 m/s. Coherent structures are detected on both sides of the interface; these are intensified and less elongated for larger Reynolds numbers. Additionally, the interface exhibits distinct behaviour with regard to the examined phases. For the gaseous phase, it behaves like a no-slip surface.