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131.
Based on consecutive extractions using bismuth diethyldithiocarbamate and thallium diethyldithiocarbamate as reagents, molybdenum was selectively and highly enriched from biological matrices, and then subjected to neutron activation analysis. Most of interfering elements, e.g., Na, K, Br, P, Fe, U, etc. were simultaneouly removed and the preconcentrated samples always showed only the r rays from molybdenum after neutron bombardment. Thus, molybdenum in the biological matrices could be accurately determined. 相似文献
132.
Competitive binding of a Tris run buffer with chiral crown ether in chiral capillary electrophoresis
In capillary electrophoresis of primary amine racemates using (+)-(18-crown-6)-tetracarboxylic acid (18C6H4) as a chiral selector, chiral recognition emanates from the differences in the complex formation between 18C6H4 and the two protonated amine enantiomers. The presence of buffer constituents such as tris(hydroxymethyl)aminomethane (Tris) or Na+, capable of forming complexes with 18C6H4, is thus detrimental to the chiral separation of primary amines. Such a competitive binding of buffer constituents was studied by comparing the electrophoretic mobilities of racemic analytes obtained in Tris/citric acid and triethylamine/citric acid buffers. We developed a simple fitting method to determine the competitive binding constant and applied it to the Tris buffer system. The competitive binding constant of Tris with 18C6H4 obtained at pH 3.0 was 27 +/- 4. 相似文献
133.
Jung SY Lim SM Albertorio F Kim G Gurau MC Yang RD Holden MA Cremer PS 《Journal of the American Chemical Society》2003,125(42):12782-12786
The molecular level details of the displacement of surface adsorbed fibrinogen from silica substrates were studied by atomic force microscopy, immunochemical assays, fluorescence microscopy, and vibrational sum frequency spectroscopy. The results showed that human plasma fibrinogen (HPF) can be readily displaced from the interface by other plasma proteins near neutral pH because the positively charged alpha C domains on HPF sit between the rest of the macromolecule and the underlying surface. The alpha C domains make weak electrostatic contact with the substrate, which is manifest by a high degree of alignment of Lys and Arg residues. Upon cycling through acidic pH, however, the alpha C domains are irreversibly removed from this position and the rest of the macromolecule is free to engage in stronger hydrogen bonding, van der Waals, and hydrophobic interactions with the surface. This results in a 170-fold decrease in the rate at which HPF can be displaced from the interface by other proteins in human plasma. 相似文献
134.
Dieter Leibfritz Erhard Haupt Norbert Dubischar Heinrich Lachmann Raymond Oekonomopulos Günther Jung 《Tetrahedron》1982,38(14):2165-2181
The uncommon amino-acid 2-methylalanine (α-aminoisobutyric acid, Aib) was investigated by 13C-NMR. The chemical shifts of amino- or carboxy-protected derivatives of Aib and of protected oligopeptides are discussed with respect to neighbouring groups and amino acids. The pH-dependence of the 13C-NMR spectra of Aib, Aib-Ala, Ala-Aib, Aib-Ala-Aib and Aib-Ala-Aib-Ala-Aib was studied. Using these examples, a new and advantageous method is demonstrated for the first time for the evalutions of NMR titration curves, which uses so-called chemical shift diagrams (CS diagrams). 相似文献
135.
S. Unterricker Kim Jung Ho W. Stolz D. Degering 《Journal of Radioanalytical and Nuclear Chemistry》1988,122(2):271-278
The underground radiation conditions in the mining district of Freiberg and in a rock salt environment of the Werra district were investigated. In a salt mine a very low natural activity level can be found. For selection of proper shielding materials a low-level -spectrometer and an optimum sample geometry must be used. The photopeak differences between sample and blank are small in most cases. Considerable differences can be found in the continuous background below 0.7 MeV. 相似文献
136.
Single nanocrystal arrays on patterned poly(ethylene glycol) copolymer microstructures using selective wetting and drying 总被引:1,自引:0,他引:1
Suh KY Khademhosseini A Eng G Langer R 《Langmuir : the ACS journal of surfaces and colloids》2004,20(15):6080-6084
Single nanocrystal arrays were fabricated on sub-microwells of poly(ethylene glycol) (PEG) copolymer using selective wetting on the hydrophilic regions of the exposed substrate surface and subsequent drying. Templates were produced by molding a thin film of a PEG-based random copolymer on hydrophilic substrates such as glass or silicon dioxide. The polymeric microstructures provide a topographical barrier around the well, which makes it possible to create nanocrystal arrays with controlled geometrical features. The size of the nanocrystal was found to decrease with decreasing well size and also decrease with decreasing topological height. A simple empirical equation was derived to predict the size of the crystal as a function of the pattern size and height, which is in good agreement with the experimental data. 相似文献
137.
Synthesis and characterization of monodisperse magnetic composite particles for magnetorheological fluid materials 总被引:2,自引:0,他引:2
Jung-Bae Jun Seong-Yong Uhm Jee-Hyun Ryu Kyung-Do Suh 《Colloids and surfaces. A, Physicochemical and engineering aspects》2005,260(1-3):157-164
Monodisperse magnetic composite particles (MCP) were prepared and characterized for a study of magnetic field-responsive fluids. Magnetic composite particles used are iron oxide-coated polymer composite particles, which were synthesized through in situ coating of iron oxide onto pre-existing polymer particles by the reduction of ferrous fluids. For a uniform and bulk coating of iron oxide, the porous structure was introduced into the substrate polymer particles through a two-step seeded polymerization method. Moreover, surface cyano-functionality was born from acrylonitrile unit of substrate polymer and it played an important role in obtaining successful uniform coating. The structure of the composite particle was analyzed by using a thermo gravimetric analysis (TGA) and a X-ray diffraction (XRD) analysis. The magnetization property of the particle was also observed. Then, the rheological properties of monodisperse magnetorheological (MR) suspensions of magnetic composite particles were examined under a magnetic field using a parallel-plate type commercial rheometer. From the rheological measurements, it was found that MR properties of the magnetic composite suspensions are dependent on the iron oxide content and the fluid composition. 相似文献
138.
Chi YS Jung YH Choi IS Kim YG 《Langmuir : the ACS journal of surfaces and colloids》2005,21(10):4669-4673
In this paper, we report surface-initiated d(A-T) polymerization by Taq DNA polymerase as a method for constructing DNA-tethered surfaces using an enzyme. The enzymatic polymerization was conducted successfully via two steps: tethering of oligo d(A-T)s onto the surface presenting carboxylic acids by amide coupling and surface-initiated polymerization using Taq DNA polymerase. In this enzymatic polymerization process, the design and construction of carboxylic acid-presenting surfaces were found to be an important factor: DNA growth did not occur on the gold surface coated only with the self-assembled monolayer (SAM) of 16-mercaptohexadecanoic acid (MHDA), but effectively proceeded on the surfaces presenting mixed SAMs of MHDA and 1-pentadecanethiol. The coupling of oligo d(A-T)s and the subsequent DNA polymerization reaction were characterized by polarized infrared external reflectance spectroscopy, ellipsometry, X-ray photoelectron spectroscopy, and atomic force microscopy. 相似文献
139.
Pyun DK Kim BJ Jung HJ Kim JH Lee JS Lee WK Lee CH 《Chemical & pharmaceutical bulletin》2002,50(3):415-418
A new series of 1beta-methylcarbapenems 1a-d bearing 5-methyl-4-mercaptopyrrolidinone rings has been prepared and evaluated for in vitro antibacterial activity and pharmacokinetic parameters. Most compounds showed excellent antibacterial activity and high stability to dehydropeptidase-1. We have synthesized optically active 5-methyl-4-hydroxypyrrolidinones from enantiomerically pure aziridine esters. 相似文献
140.
The energy levels of a series of para substituted N,N-dimethylanilines p-MHnMe3?n C6H4NMe2 (n = 0?3, M = C or Si) for the ground and lower lying excited states have been determined in acetonitrile solution. The levels for the carbon compounds are all slightly destailized relative to N,N-dimethylaniline and the effects are rather insensitive to n. The stabilizations produced by silicon substituents on all levels are markedly affected by silicon's substituents, showing increasing perturbations with increasing n. It is concluded that variations in the interaction of the σ* system of the silyl substituent with the aniline π system, and not d orbital interactions, account for the trends observed. 相似文献