Laser shadowgraph and schlieren studies of gravity-related flow during solidification

Shadowgraph and schlieren techniques were used to observe gravity-related flow arising during solidification. The purpose of these studies was to elucidate the results of previous low gravity solidification experiments. Shadowgraph and schlieren techniques were selected as most suitable for operation in the anticipated experimental environment. A laser shadowgraph/schlieren system was built and flown on KC-135 low gravity simulation flights. A solution of ammonium chloride and water was cooled during the experiment, causing solidification. Growth plumes in the solution were observed and photographed using shadowgraph and schlieren techniques. Results are presented and related to previous work.     

Optimal allocation of reliability tasks to mitigate faults during system development

^** Email: walter.johnston{at}baesystems.com^*** Email: j.quigley{at}strath.ac.uk^**** Email: lesley.walls{at}strath.ac.uk This paper considers reliability planning for a concept designfor a new system where a portfolio of possible reliability developmenttasks exists; the goal is to find a selection and sequence oftasks to achieve reliability targets subject to time constraintsat minimal cost. This is non-trivial given that each task potentiallycan expose several different weaknesses and each weakness potentiallycan be exposed by several different tasks. We use a Bayesianpoint process model to estimate the system reliability. Theprior distribution maps to a fault register and relates directlyto a set of potential engineering modifications.The likely impactof each task can be assessed using the point process model.An integer programming approach is used to sequence and scheduletasks under the constraint that contractual reliability requirementsmust be met. An illustrative example is provided and an extensionto system availability is proposed.     

Diastereoselective synthesis of (+/-)-(3-aminocyclopentane)alkylphosphinic acids, conformationally restricted analogues of GABA

A divergent synthesis of both diastereoisomers of (+/-)-(3-aminocyclopentane)alkylphosphinic acid is described. Both diastereoisomers are obtained in 5 steps from the key (+/-)-(3-hydroxycyclopent-1-ene)alkylphosphinate esters which are prepared via a palladium catalysed C-P bond forming reaction.     

Probing the dimensions of semi-rigid inner functionalised U-shaped bis-porphyrin cavities

The synthesis of a series of open U-shaped bis-porphyrin cavity molecules is described, with bridged bicyclic backbones to confer rigidity, and a pendant substituted aromatic probe unit suspended on the inside of the cavity. The dimensions and flexibility of the bis-zincporphyrin cavity were probed using several different techniques. Initially the molecular ruler concept was employed, using flexible bidentate ligands as guests with a range of possible linear dimensions. Secondly, NMR methods were employed with rigid bidentate ligand guests of fixed lengths, and thirdly diffusion based NMR methods were utilised. The range of inter-porphyrin distances estimated by these methods suggests that these types of open-cavity systems have a surprising degree of flexibility.     

Characterizing potential surface topographies through the distribution of saddles and minima

Three related clusters of thirteen particles bound by pairwise Morse potentials with different ranges are the vehicles for relating the dynamics and kinetics of these clusters to the topographies of their energy landscapes. The analyses are based on the distributions of minima and saddles, on the asymmetries of the barriers and the kinetics of passage among the energy bands that the distributions of minima display. While all three of the examples are essentially structure-seekers, the extent of this character is clearly related to the range of the potential.