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911.
Korol Waldemar Rubaj Jolanta Bielecka Grażyna Walczyński Sławomir Reszko-Zygmunt Joanna Dobrowolski Ryszard 《Accreditation and quality assurance》2017,22(2):83-89
Accreditation and Quality Assurance - On the basis of long-standing proficiency testings (PTs) for the small number of PT participants p... 相似文献
912.
913.
Niladri S. Karan Aaron M. Keller Siddharth Sampat Oleksiy Roslyak Ayesha Arefin Christina J. Hanson Joanna L. Casson Anil Desireddy Yagnaseni Ghosh Andrei Piryatinski Rashi Iyer Han Htoon Anton V. Malko Jennifer A. Hollingsworth 《Chemical science》2015,6(4):2224-false
Hybrid semiconductor–metal nanoscale constructs are of both fundamental and practical interest. Semiconductor nanocrystals are active emitters of photons when stimulated optically, while the interaction of light with nanosized metal objects results in scattering and ohmic damping due to absorption. In a combined structure, the properties of both components can be realized together. At the same time, metal–semiconductor coupling may intervene to modify absorption and/or emission processes taking place in the semiconductor, resulting in a range of effects from photoluminescence quenching to enhancement. We show here that photostable ‘giant’ quantum dots when placed at the center of an ultrathin gold shell retain their key optical property of bright and blinking-free photoluminescence, while the metal shell imparts efficient photothermal transduction. The latter is despite the highly compact total particle size (40–60 nm “inorganic” diameter and <100 nm hydrodynamic diameter) and the very thin nature of the optically transparent Au shell. Importantly, the sensitivity of the quantum dot emission to local temperature provides a novel internal thermometer for recording temperature during infrared irradiation-induced photothermal heating. 相似文献
914.
Joanna Legat Magdalena Matczuk Andrei Timerbaev Maciej Jarosz 《Chromatographia》2017,80(11):1695-1700
A full understanding and mediation of nanoparticle–serum protein interactions is key to design nanoparticles with vivid functions within the body, and to solve this problem one needs to differentiate and characterize individual nano-protein conjugates. In this paper, the authors applied capillary electrophoresis combined with inductively coupled plasma mass spectrometry detection to study the behavior of gold nanoparticles of different geometry, size and surface functionalization upon interacting with serum proteins and their mixtures. Due to high-resolution and -sensitivity benefits of this combined technique baseline separations were attained for free nanoparticles (at real-life doses) and different protein conjugates, and the conversion into the protein-bound form was scrutinized in terms of reaction time. 相似文献
915.
Sokolov FD Babashkina MG Safin DA Rakhmatullin AI Fayon F Zabirov NG Bolte M Brusko VV Galezowska J Kozlowski H 《Dalton transactions (Cambridge, England : 2003)》2007,(41):4693-4700
Reaction of the potassium salts of N-thiophosphorylated thioureas of common formula RC(S)NHP(S)(OiPr)(2) [R = morpholin-N-yl (HL(a)), piperidin-N-yl (HL(b)), NH(2) (HL(c)), PhCH(2)NH (HL(d))] with Cu(PPh(3))(3)I in aqueous EtOH/CH(2)Cl(2) leads to mononuclear [Cu(PPh(3))(2)L-S,S'] complexes. Using copper(i) iodide instead of Cu(PPh(3))(3)I, polynuclear complexes [Cu(n)(L-S,S')(n)] were obtained. The structures of these compounds were investigated by ES-MS, elemental analyses, 1H and 31P NMR in solution, IR and 31P solid-state MAS NMR spectroscopy. The crystal structures of [Cu(3)L(3)(a)] and [Cu(PPh(3))(2)L(b)] were determined by single-crystal X-ray diffraction. 相似文献
916.
Organ MG Abdel-Hadi M Avola S Hadei N Nasielski J O'brien CJ Valente C 《Chemistry (Weinheim an der Bergstrasse, Germany)》2007,13(1):150-157
An easily employed, highly versatile Kumada-Tamao-Corriu (KTC) protocol utilizing the PEPPSI (Pyridine, Enhanced, Precatalyst, Preparation, Stabilization and Initiation) precatalysts 1 and 2 is detailed. The ease-of-use of these catalysts and the synthesis of a wide range of hindered biaryls, large coupling partners and drug-like heterocycles, in high yield, makes the PEPPSI-KTC protocol very attractive. The high reactivity of the PEPPSI system allowed a tetra-ortho-substituted heterocycle, 11 to be synthesized at room temperature for the first time using any protocol. The PEPPSI protocols also tolerated the Boc protecting group and phenols required no protection in modified conditions. A relatively large scale (10 g) reaction was also performed with no loss in performance. Furthermore, PEPPSI-IPr, 1, was compared to previously reported highly active phosphine ligands 42, 43, and 44 and was shown to result in significantly better yields under identical conditions. Finally, we demonstrated that the PEPPSI catalyst system is very adept at performing sequential KTC coupling reactions, analogous to multicomponent reactions, which allow complex polyaryl and polyheteroaryl architectures to be produced in one single operation. 相似文献
917.
Zawacka-Pankau J Kowalska A Issaeva N Burcza A Kwiek P Bednarz N Pramanik A Banecki B Podhajska AJ 《Journal of photochemistry and photobiology. B, Biology》2007,86(1):35-42
Fhit, the product of tumor suppressor fragile histidine triad (FHIT) gene, exhibits antitumor activity of still largely unknown cellular background. However, it is believed that Fhit-Ap(3)A or Fhit-AMP complex might act as a second class messenger in cellular signal transduction pathway involved in cell proliferation and apoptosis. We demonstrate here for the first time that the photosensitizer, protoporphyrin IX (which is a natural precursor of heme) binds to Fhit protein and its mutants in the active site in vitro. Furthermore, PpIX inhibits the enzymatic activity of Fhit. Simultaneously, PpIX shows lower binding capacity to mutant Fhit-H96N of highly reduced hydrolase activity. In cell-based assay PpIX induced HeLa cell death in Fhit and Fhit-H96N-dependent manner which was measured by means of MTT assay. Moreover, HeLa cells stably expressing Fhit or mutant Fhit-H96N were more susceptible to protoporphyrin IX-mediated photodynamic therapy (2J/cm(2)) than parental cells. 相似文献
918.
Sionkowska A Skopinska J Wisniewski M Leznicki A 《Journal of photochemistry and photobiology. B, Biology》2007,86(2):186-191
An investigation into the influence of UV irradiation on elastin hydrolysates in the presence of collagen was carried out using UV-Vis spectroscopy and spectrofluorometry. It was found that the absorbance of elastin hydrolysates in solution increased during irradiation more than the absorbance of the elastin/collagen blend. The fluorescence of elastin hydrolysates was observed at 305nm and at 380nm after excitation at 270nm. For the elastin/collagen mixture in solution, fluorescence spectrum shows only one maximum at 305nm. UV irradiation caused fluorescence fading at 305nm. For irradiated elastin the fluorescence at 305nm decreased faster than for the irradiated elastin/collagen mixture. The maximum of the fluorescence peak was shifted for elastin by 4nm, whereas for the elastin/collagen blends the shift was only 1-2nm. All the obtained results point out the ability of mixing elastin and collagen, and suggest that the elastin/collagen mixture in solution is less sensitive to UV irradiation than elastin hydrolysates alone. 相似文献
919.
Ramos JM Versiane O Felcman J Téllez Soto CA 《Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy》2007,68(5):1370-1378
The trans-bis(glycine)nickel(II) complex was synthesized, and the Fourier transform infrared spectra in the regions 4000-370 cm(-1) and 700-30 cm(-1) were measured. Band deconvolution analysis and the second derivative of the infrared spectrum were also performed. The determination of the geometrical structure in the trans position of the glycine ligands around Ni(II) for the trans-bis(glycine)nickel(II) complex as well as the vibrational assignment were assisted by RHF/6-311G and by Density Functional Theory calculations, DFT:B3LYP/6-31G and 6-311G basis sets. A full discussion of the framework vibrational modes was done using as criteria the geometry study of distorted structures generated for the vibrational modes. Incidentally, Normal Coordinate Analysis was carried out for the Ni(N)(2)(O)(2) structural fragment. The calculated DFT spectra in the high- and low-energy regions agree with the observed ones. 相似文献
920.
Kamieńska-Piotrowicz E Stangret J Szymańska-Cybulska J 《Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy》2007,66(1):1-8
FT-IR spectra of Co(CF(3)SO(3))(2)-N,N-dimethylformamide (DMF)-methanol (MeOH) solutions have been measured over the whole range of solvent composition. The data together with the obtained previously spectra of DMF-MeOH mixtures have been analyzed using the difference spectra method in the region of CO and OH stretching bands. The number of DMF and MeOH molecules in the first solvation sphere of Co(II) ion versus solvent composition has been determined. The second solvation sphere has been revealed and characterized quantitatively. Solvation of trifluoromethanesulfonate (triflate) ion as well as ion association in DMF solution have been also studied. 相似文献