Determination of N-Methylpyrrolidine in Cefepime for Injection by Capillary Electrophoresis with Indirect UV Detection

N-Methylpyrrolidine in cefepime for injection was determined by capillary electrophoresis with indirect UV detection. Best results were achieved with background electrolyte consisting of 10 mM creatinine adjusted to pH 3.8 with formic acid and an applied voltage of 30 kV in a bare fused-silica capillary. Indirect UV detection was performed at a wavelength of 225 nm. The application of a small amount of inlet pressure during the separation assisted the attainment of a stable baseline. The optimized method was validated regarding selectivity, linearity, accuracy, precision, ruggedness, repeatability and detection limits. Careful control of capillary conditioning enabled migration time precision values of <0.2% RSD. The use of an internal standard enabled precision values of <1% RSD to be obtained for peak area ratios.     

Crystal Structure of Dimethylamine 3,5-Dinitrobenzoic Acid Organic Adduct

1 INTRODUCTION Nonlinear optics (NLO) is at the forefront of cur- rent researches because of its importance in provi- ding the key functions of frequency shifting, optical modulation, optical switching, optical logic and op- tical memory for the emerging …     

催化燃烧去除VOCs污染物的最新进展

催化燃烧是目前最有效的处理挥发性有机物(VOCs)技术之一. 本文从催化剂活性组分、催化剂载体、有效组分颗粒大小、水蒸汽的影响及催化燃烧反应中的积碳等几个方面, 对近年来催化燃烧处理VOCs的研究进行了总结. 分析表明: 贵金属催化剂的研究主要着重于选择有效的载体和双组分贵金属催化剂; 非贵金属催化剂的研究主要集中在高活性的过渡金属复合氧化物、钙钛矿和尖晶石型等催化剂的研制, 还有这些活性组分粒径大小及载体对催化燃烧VOCs反应活性的影响;此外, 在实际应用中,水蒸汽和催化剂积碳失活等问题对催化燃烧VOCs的反应也有很大影响. 本文的评述将为选择合适的催化燃烧技术处理VOCs污染物提供一定参考.     

DMF-甲醇体系粘度与核磁共振化学位移的同时关联

提出了一个基于局部组成概念上的核磁共振模型. 利用该模型和以前别人提出的局部组成型粘度方程, 成功地同时关联属于传递性质的粘度数据和属于波谱性质的核磁共振化学位移数据，关联所得到化学位移的平均绝对偏差小于0.0072，粘度的平均绝对偏差小于0.0006 mPa•s，结果表明提出的局部组成模型是合理的.     

氮化铁催化剂的制备及其苯胺催化加氢性能

用α－Ｆｅ２Ｏ３与氨气程序升温还原方法制备出不同温度氮气的氮化铁系列催化剂。通过ＸＲＤ测试对氮化过程中的晶相转变进行了分析。在中压反应装置上考察了氮化铁系列催化剂上苯胺加氢活性以及反应条件对苯胺加氢反应活性的影响。结果表明，在７００℃氮化制香的氮化铁催化剂显示有较高的苯胺加氢活性，在氢压为３．０ＭＰａ，温度为２５０℃，ｎ（Ｈ２）／ｎ（ｏｉｌ）＝１８，液体空速（ＷＨＳＶ）为０．３ｈ＾－１时，该催化剂     

催化燃烧去除VOCs污染物的最新进展

催化燃烧是目前最有效的处理挥发性有机物(VOCs)技术之一. 本文从催化剂活性组分、催化剂载体、有效组分颗粒大小、水蒸汽的影响及催化燃烧反应中的积碳等几个方面, 对近年来催化燃烧处理VOCs的研究进行了总结. 分析表明: 贵金属催化剂的研究主要着重于选择有效的载体和双组分贵金属催化剂; 非贵金属催化剂的研究主要集中在高活性的过渡金属复合氧化物、钙钛矿和尖晶石型等催化剂的研制, 还有这些活性组分粒径大小及载体对催化燃烧VOCs反应活性的影响;此外, 在实际应用中,水蒸汽和催化剂积碳失活等问题对催化燃烧VOCs的反应也有很大影响. 本文的评述将为选择合适的催化燃烧技术处理VOCs污染物提供一定参考.     

Atomic absorption determination of traces of cadmium in urine after electrodeposition onto a tungsten wire

A three-coil tungsten wire is used as electrode for the preconcentration of cadmium, which is then placed in a graphite tube for atomization and atomic absorption measurement. The heating parameters of the graphite furnace are optimized using the Modified and Weighted Centroid Simplex Method (MWCS), and computer program for automatic calculation. Sulphuric acid is selected as the supporting electrolyte for electrodeposition. The linear range of the calibration graph is 0.00-0.55 ng/ml. The detection limit is 0.01 ng/ml. For 0.1 ng/ml cadmium the coefficient of variation is 3.35% for ten parallel determinations. No interference occurs in the presence of more than 20 coexisting ions. Traces of cadmium in urine of normal people and in river water and the recoveries for cadmium are determined. The results are satisfactory.     

新型6-氟-4(3H)-喹唑啉酮类Schiff碱的合成及其抑菌活性

以2-氨基-5-氟苯甲酸为起始原料，与醋酐酰化关环制得6-氟-2-甲基噁嗪-4-酮(1)； 1在80%水合肼中回流反应制得6-氟-2-甲基-3-氨基-4(3H)-喹唑啉酮(2)； 2分别与羟基芳醛和杂环芳醛反应合成了6个6-氟-4(3H)-喹唑啉酮类Schiff碱（3a~3f），其中3b~3f为新化合物，其结构经¹H NMR， ¹³C NMR， IR和元素分析表征。采用琼脂扩散法研究了3a~3f对大肠杆菌、金黄色葡萄球菌和枯草杆菌的抑制活性。结果表明：用药浓度为400 μg·mL^-1时，3a~3f对受试菌种均有一定的抑制活性，其中6-氟-2-甲基-3-(4-吡咯苯亚甲氨基)-4(3H)-喹唑啉酮(3c)抑菌活性最强，对大肠杆菌和枯草杆菌的抑菌圈直径分别为9.38 mm和9.00 mm。     

A Home-made Simple Set-up for Measurement of Electrochemical Surface Tension Spectrum on a Mercury Drop Electrode

A setup for recording surface tension curves at a mercury drop during potential scanning is designed based on photo-sensitive detection system. Surface tension spectrum at Hg drop can be recorded by voltammetric study. A Yb(III)-NO2- catalytic reduction system was used for characterization. The simple, sensitive technique can be expected to provide fresh information on molecular interactions at electrode surfaces.     

运动对去卵巢大鼠骨元素代谢的影响

用测定骨元素含量的方法，分析了运动对正常大鼠和切除双侧卵巢后的大鼠骨元素代谢的影响。将健康4个月龄雌性SD大鼠44只随机分成5组：（1）非去势非运动组；（2）非去势＋运动组；（3）假去势非运动组；（4）去势非运动组；（5）去势＋运动组。运动组用大鼠专用跑台中等运动强度训练，持续10周。结果表明，去卵巢大鼠骨Ca,Mg,S,Mn,Zn等含量显著降低，P含量显著增加。运动训练可使去卵巢大鼠降低的骨Ca,Mg,S,Mn,Zn等含量显著回升，骨P含量显著回降。提示中等强度运动训练可对抗由于去卵巢所引起的骨元素代谢紊乱。