全文获取类型
收费全文 | 215篇 |
免费 | 5篇 |
专业分类
化学 | 178篇 |
晶体学 | 1篇 |
力学 | 1篇 |
数学 | 8篇 |
物理学 | 32篇 |
出版年
2023年 | 4篇 |
2022年 | 6篇 |
2021年 | 4篇 |
2020年 | 3篇 |
2019年 | 5篇 |
2018年 | 2篇 |
2017年 | 2篇 |
2016年 | 3篇 |
2015年 | 6篇 |
2014年 | 4篇 |
2013年 | 11篇 |
2012年 | 17篇 |
2011年 | 16篇 |
2010年 | 14篇 |
2009年 | 12篇 |
2008年 | 14篇 |
2007年 | 14篇 |
2006年 | 12篇 |
2005年 | 14篇 |
2004年 | 10篇 |
2003年 | 10篇 |
2002年 | 9篇 |
2001年 | 2篇 |
2000年 | 3篇 |
1999年 | 2篇 |
1998年 | 2篇 |
1997年 | 3篇 |
1996年 | 1篇 |
1993年 | 1篇 |
1992年 | 1篇 |
1990年 | 1篇 |
1985年 | 4篇 |
1984年 | 3篇 |
1976年 | 1篇 |
1973年 | 3篇 |
1969年 | 1篇 |
排序方式: 共有220条查询结果,搜索用时 15 毫秒
31.
32.
Discrimination of basal cell carcinoma from normal dermal stroma by quantitative multiphoton imaging
Lin SJ Jee SH Kuo CJ Wu RJ Lin WC Chen JS Liao YH Hsu CJ Tsai TF Chen YF Dong CY 《Optics letters》2006,31(18):2756-2758
We performed multiphoton fluorescence (MF) and second-harmonic generation (SHG) imaging on human basal cell carcinoma samples. In the dermis, basal cell carcinomas can be identified by masses of autofluorescent cells with relatively large nuclei and marked peripheral palisading. In the normal dermis, SHG from dermal collagen contributes largely to the multiphoton signal. However, within the cancer stroma, SHG signals diminish and are replaced by autofluorescent signals, indicating that normal collagen structures responsible for SHG have been altered. To better delineate the cancer cells and cancer stroma from the normal dermis, a quantitative MF to SHG index is developed. We demonstrate that this index can be used to differentiate cancer cells and adjacent cancer stroma from the normal dermis. Our work shows that MF and SHG imaging can be an alternative for Mohs' surgery in the real-time guidance of the secure removal of basal cell carcinoma. 相似文献
33.
Matthias Mendt Bettina Jee Dieter Himsl Lutz Moschkowitz Tim Ahnfeldt Norbert Stock Martin Hartmann Andreas Pöppl 《Applied magnetic resonance》2014,45(3):269-285
Continuous-wave electron paramagnetic resonance spectroscopy is applied to explore the adsorption of carbon dioxide (CO2) over the metal organic framework (MOF) MIL-53. Therefore, paramagnetic Cr3+ ions, which replace a small amount of the bulk Al3+ ions in MIL-53(Al/Cr), are used as magnetically active probes. CO2 was adsorbed on samples of MIL-53(Al/Cr) at equilibrium pressures between 0 and 2.5 bar. The transformation from the large pore phase to the narrow pore phase of MIL-53 was observed by electron paramagnetic resonance spectroscopy at small CO2 pressures between 0.2 and 0.4 bar, which is in accordance with adsorption results reported in literature. By analyzing the electron paramagnetic resonance signal intensities of the corresponding Cr3+ probes, the ratio between the amount of the narrow pore phase and the large pore phase before and after this phase transformation was quantified. A small fraction of the large pore phase remains even after this phase transition. CO2 adsorption at 77 K indicates the occurrence of the transformation of this MOF from a narrow pore phase to a large pore phase triggered by the adsorbed CO2. Similar observations were already made using powder X-ray diffraction or infrared spectroscopy. But in contrast to these methods electron paramagnetic resonance spectroscopy on Cr3+ seems to be very sensitive not only to large differences between crystallographic conformations like large pores and narrow pores but also to different amounts and configurations of CO2 molecules trapped in the same structural phase of MIL-53, taking advantage of the high sensitivity of the fine structure interaction of Cr3+. 相似文献
34.
Selden NS Todhunter ME Jee NY Liu JS Broaders KE Gartner ZJ 《Journal of the American Chemical Society》2012,134(2):765-768
Cell adhesion organizes the structures of tissues and mediates their mechanical, chemical, and electrical integration with their surroundings. Here, we describe a strategy for chemically controlling cell adhesion using membrane-anchored single-stranded DNA oligonucleotides. The reagents are pure chemical species prepared from phosphoramidites synthesized in a single chemical step from commercially available starting materials. The approach enables rapid, efficient, and tunable cell adhesion, independent of proteins or glycans, by facilitating interactions with complementary labeled surfaces or other cells. We demonstrate the utility of this approach by imaging drug-induced changes in the membrane dynamics of non-adherent human cells that are chemically immobilized on a passivated glass surface. 相似文献
35.
Dielectric-breakdown-like forming process in the unipolar resistance switching of Ta2O5−x thin films
Moon Jee YoonShin Buhm Lee Hyang Keun YooSoobin Sinn Bo Soo Kang 《Current Applied Physics》2012,12(3):846-848
We report unipolar resistance switching (URS) in Ta2O5−x thin films. The current increased suddenly when we applied voltages up to 5-7 V to the pristine state of Pt/Ta2O5−x/Pt, Ni/Ta2O5−x/Pt, and Ti/Ta2O5−x/Pt cells. Just after this forming process, we observed a repetitive URS occurring independently of the electrodes. We found that the required voltages for the forming process did not depend on the top electrode type, but on the film thickness. These results suggest that the forming process is driven by a dielectric-breakdown-like phenomenon, and that URS occurs due to the formation and rupture of conducting channels inside the Ta2O5−x thin film. 相似文献
36.
JS Kim TG Kim WH Kong TG Park YS Nam 《Chemical communications (Cambridge, England)》2012,48(74):9227-9229
A nanoporous membrane is coated with catechol-tethered poly(N-isopropylacrylamide). The thermosensitive variation of surface wettability determines the hindered diffusivity of dextran (40 kDa) through the nanopores. 相似文献
37.
Weihong He Xiuping Lin Tunhai Xu Jee H. Jung Hao Yin Bin Yang Yonghong Liu 《Chemistry of Natural Compounds》2012,48(2):208-210
A new norsesterterpenoid 1 was isolated from the Sarcotragus sponge by bioactivity-guided fractionation. The structure was established on the basis of NMR and MS analysis. 相似文献
38.
Jin‐Woong Kim Mi‐Ok Jung Yong‐Jin Kim Jee‐Hyun Ryu Junoh Kim Ih‐Seop Chang Ok‐Sub Lee Kyung‐Do Suh 《Macromolecular rapid communications》2005,26(15):1258-1261
Summary: This communication describes an enzyme stabilization method that allows the use of enzymes irrespective of environmental factors, especially heat, while maintaining their activity for a long time. We have designed enzyme microcapsules that consist of papain enzyme cores, poly(propylene glycol) interlayers, and poly(ε‐caprolactone) walls. By confocal laser scanning microscopy measurements and the thermal stability of papain‐loaded microcapsules, it is demonstrated that the papain is surrounded by a hydrophobic polyol layer and stabilized by the exclusive volume effect. In our study, improved thermal stability can be obtained by using more hydrophobic long‐chained polyols, which is understood to be attributed to the effective formation of a hydrophobic polyol layer between the papain and the polymer wall by means of conformational anchoring in the interface.
39.
Dzan Jin Jee 《Journal of Geometry》1985,24(1):6-13
In this work we set up trigonometric laws and a new parallel angle formula on S
1
2
in terms of Lorentz lengths and pseudo-angles. Thus all the laws have the same form as those of spherical trigonometry. The new parallel angle formula, however, contrasts well with that of Lobatschevsky in hyperbolic geometry. 相似文献
40.
Jin‐Woong Kim Kwang‐Sup Lee Hee‐Kyung Ju Jee‐Hyun Ryu Sang‐Hoon Han Ih‐Seop Chang Hak‐Hee Kang Seong‐Geun Oh Kyung‐Do Suh 《Journal of polymer science. Part A, Polymer chemistry》2004,42(9):2202-2213
A new microencapsulation technique is presented in which cholesteryl nonanoate (CN)/poly(methyl methacrylate) (PMMA) microcapsules are produced by the induction of phase separation between CN and PMMA within the droplets during the polymerization. The concentration of CN is the most important factor determining the final morphology of the microcapsules. For example, a polynuclear type is obtained at a low concentration (<20 wt %), a mononuclear type is obtained at a medium concentration (20–30 wt %), and an irregular phase is obtained at a high concentration (>40 wt %). To evaluate the effectiveness of the technique for stabilizing an unstable drug, we selected retinol (vitamin A) as a model drug and loaded it into the CN/PMMA microcapsules. We used a process called solute codiffusion, in which a fine solvent emulsion containing the retinol was diffused uniformly into the CN/PMMA microcapsules. The loading efficiency of retinol was predicted successfully with the aid of a thermodynamic equation. In the thermal stability test of retinol, we found that an effective association with the CN phase was the most important factor determining the limit of its molecular stability. The technique reported in this article has great potential for the microencapsulation of soft materials via a simple process and for the stabilization of unstable drugs. © 2004 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 42: 2202–2213, 2004 相似文献