Asymptotic and exponential decay in mean square for delay geometric Brownian motion

Applications of Mathematics - We derive sufficient conditions for asymptotic and monotone exponential decay in mean square of solutions of the geometric Brownian motion with delay. The conditions...     

Preparation and characterization of theβ-cyclodextrin inclusion complex with sulfafurazole

The 1 : 1 inclusion complex involving sulfafurazole (SF) and-cyclodextrin (-CD) is prepared by the freeze-drying method and characterized on the basis of its chemical analysis, thermal behavior, infrared spectrum, X-ray powder pattern and¹³C NMR spectrum in DMSO-d₆ solution. The stability constant of the inclusion complex was determined by the solubility method. The effect of cyclodextrin on the UV absorption spectrum of sulfafurazole was also observed.     

A heuristic method for dispatching repair men

A company has to provide service to its customers. A service consists of a visit to the customer plus the spending of some given time at the scene. The future customer demand is not known but the probability distribution for the demand may be known. When a customer call comes in, the company must immediately specify a time window within which the start of service will be provided. The problem is for a fixed service level to determine an optimal strategy of route design and time window setting so that the total distance travelled is minimized over the time horizon given. A heuristic method BARTOC (Booking Algorithm for Routing and Timing Of Customers) to solve the problem mentioned above is suggested. BARTOC is based on a cluster-first route-second approach. Some computational results are presented. The results indicate that BARTOC produces high quality solutions.Peter Matthiesen, Inc.Dano Chemo, Inc.     

Kneser-type oscillation criteria for self-adjoint two-term differential equations

It is proved that the even-order equationy ⁽²ⁿ⁾ +p(t)y=0 is (n,n) oscillatory at if

Intersection Dimensions of Graph Classes

The intersection dimension of a graphG with respect to a classA of graphs is the minimumk such thatG is the intersection of at mostk graphs on vertex setV(G) each of which belongs toA. We consider the question when the intersection dimension of a certain family of graphs is bounded or unbounded. Our main results are (1) ifA is hereditary, i.e., closed on induced subgraphs, then the intersection dimension of all graphs with respect toA is unbounded, and (2) the intersection dimension of planar graphs with respect to the class of permutation graphs is bounded. We also give a simple argument based on [Ben-Arroyo Hartman, I., Newman, I., Ziv, R.:On grid intersection graphs, Discrete Math.87 (1991) 41-52] why the boxicity (i.e., the intersection dimension with respect to the class of interval graphs) of planar graphs is bounded. Further we study the relationships between intersection dimensions with respect to different classes of graphs.     

Asymptotics of heavy atoms in high magnetic fields: II. Semiclassical regions

The ground state energy of an atom of nuclear chargeZe in a magnetic fieldB is exactly evaluated to leading order asZ in the following three regions:BZ ^4/3,BZ ^4/3 andZ ^4/3BZ³. In each case this is accomplished by a modified Thomas-Fermi (TF) type theory. We also analyze these TF theories in detail, one of their consequences being the nonintuitive fact that atoms are spherical (to leading order) despite the leading order change in energy due to theB field. This paper complements and completes our earlier analysis [1], which was primarily devoted to the regionsBZ ³ andBZ³ in which a semiclassical TF analysis is numerically and conceptually wrong. There are two main mathematical results in this paper, needed for the proof of the exactitude of the TF theories. One is a generalization of the Lieb-Thirring inequality for sums of eigenvalues to include magnetic fields. The second is a semiclassical asymptotic formula for sums of eigenvalues that isuniform in the fieldB.Work partially supported by U.S. National Science Foundation grant PHY90-19433 A02Work partially supported by U.S. National Science Foundation grant DMS 92-03829Work partially supported by the Heraeus Stiftung and the Research Fund of the University of Iceland.     

Dynamic structure factor in a random diffusion model

Let {X _t:0} denote random walk in the random waiting time model, i.e., simple random walk with jump ratew ^–1(X _t), where {w(x):x^d} is an i.i.d. random field. We show that (under some mild conditions) theintermediate scattering function F(q,t)=E ₀ (q^d) is completely monotonic int (E ₀ denotes double expectation w.r.t. walk and field). We also show that thedynamic structure factor S(q, w)=2 ₀ cos(t)F(q, t) exists for 0 and is strictly positive. Ind=1, 2 it diverges as 1/||^1/2, resp. –ln(||), in the limit 0; ind3 its limit value is strictly larger than expected from hydrodynamics. This and further results support the conclusion that the hydrodynamic region is limited to smallq and small such that ||D |q|², whereD is the diffusion constant.     

Structural aspects of antibody-antigen interaction revealed through small random peptide libraries

Summary Two small random peptide libraries, one composed of 4550 dodecapeptides and one of 8000 tripeptides, were synthesized in newly developed credit-card format miniPEPSCAN cards (miniPEPSCAN libraries). Each peptide was synthesized in a discrete well (455 peptides/card). The two miniPEPSCAN libraries were screened with three different monoclonal antibodies (Mabs). Two other random peptide libraries, expressed on the wall of bacteria (recombinant libraries) and composed of 10⁷ hexa- and octapeptides, were screened with the same three Mabs. The aim of this study was to compare the amino acid sequence of peptides selected from small and large pools of random peptides and, in this way, investigate the potential of small random peptide libraries. The screening of the two miniPEPSCAN libraries resulted in the identification of a surprisingly large number of antibody-binding peptides, while the screening of the large recombinant libraries, using the same Mabs, resulted in the identification of only a small number of peptides. The large number of peptides derived from the small random peptide libraries allowed the determination of consensus sequences. These consensus sequences could be related to small linear and nonlinear parts of the respective epitopes. The small number of peptides derived from the large random peptide libraries could only be related to linear epitopes that were previously mapped using small libraries of overlapping peptides covering the antigenic protein. Thus, with respect to the cost and speed of identifying peptides that resemble linear and nonlinear parts of epitopes, small diversity libraries based on synthetic peptides appear to be superior to large diversity libraries based on expression systems.Abbreviations ABTS 2,2-azino-di-3-ethylbenzthiazoline sulfonate - EGF epidermal growth factor - Mab monoclonal antibody - OD_ccd optical density obtained using CCD camera - RAMPO rabbit-antimouse peroxidase - SDS sodium dodecylsulfate - TGEV transmissible gastroenteritis virus