6-氯吡啶-3-亚甲基取代杂环化合物的合成

以2-氯-5-氯甲基吡啶、苯基哌嗪、1-苯基-3-甲基-2-吡唑酮为原料,通过3条路线合成了6个新的6-氯吡啶-3-亚甲基取代杂环化合物,其结构经1H NMR,MS和元素分析表征.     

钾离子响应型单分散智能凝胶微球制备与表征

采用沉淀共聚反应成功地制备出了温敏单体N-异丙基丙烯酰胺(NIPAM)和具有钾离子识别能力的苯并-18-冠-6-丙烯酰胺(BCAm)交联共聚的P(NIPAMc-o-BCAm)凝胶微球。采用动态激光光散射(DLS)方法研究了凝胶微球的温敏及钾离子响应特性。实验结果表明,P(NIPAM-co-BCAm)凝胶微球具有很好的单分散性和温敏特性,并且在33℃的5mM钾离子溶液中,其水化直径比在纯水中显著增大,显示出了离子响应性。     

A Strong-Acid-Resistant [Th6] Cluster-Based Framework for Effectively and Size-Selectively Catalyzing Reductive Amination of Aldehydes with N,N-Dimethylformamide

Utilization of N,N-dimethylformamide (DMF) as an amine source and reductant for synthesizing tertiary amines is a promising way to replace the substrates formaldehyde and dimethylamine, and it is desirable to seek porous acid-resistant catalysts for heterogeneous catalysis of this reaction. Herein, a robust metal–organic framework (MOF) {[Th₆O₄(OH)₄(H₂O)₆(BCP)₃]⋅10 DMF}_n ( 1 ) containing stacked nanocages with a diameter of 1.55 nm was constructed. Compound 1 can maintain its single-crystal structure even kept in air at 400 °C for 3 h, and in DMF or water at 200 °C for 7 days. Density functional theory (DFT) calculations suggested that the high interaction energy between the [Th₆O₄(OH)₄(H₂O)₆]¹²⁺ clusters and ligands was responsible for the excellent stability of 1 . Catalytic investigations revealed that 1 can effectively and size-selectively catalyze the reductive amination of aldehydes with DMF, and it can be reused at least five times without obvious loss in catalytic activity.     

The Incompressible Limits of Compressible Navier-Stokes Equations in the Whole Space with General Initial Data

It is showed that, as the Mach number goes to zero, the weak solution of the compressible Navier-Stokes equations in the whole space with general initial data converges to the strong solution of the incompressible Navier-Stokes equations as long as the later exists. The proof of the result relies on the new modulated energy functional and the Strichartz＇s estimate of linear wave equation.