1,2,4-Azadiphosphole

tert-Butylaminophosphaalkyne 4 is shown to dimerize in alkaline medium to 1-tert-butyl-3-tert-butylamino-1,2,4-azadiphosphole 1 —the first representative of 1,2,4-azadiphospholes. The structure of 1 has been determined by IR and ³¹P NMR spectroscopy and by X-ray crystallography. Compound 1 crystallizes in the triclinic space group P¯1 with a = 10.356(7), b = 11.817(5), c = 11.830(3) Å, α = 88.51(3), β = 78.61(4), γ = 77.05(4)°, V = 1383(1) ų, Z = 4 (two independent molecules).     

Greatly attenuated experimental autoimmune encephalomyelitis in aquaporin-4 knockout mice

Background  

The involvement of astrocyte water channel aquaporin-4 (AQP4) in autoimmune diseases of the central nervous system has been suggested following the identification of AQP4 autoantibodies in neuromyelitis optica, an inflammatory demyelinating disease.     

Phosphorylated Allenes in the Cycloaddition Reactions

Abstract

The reactions of phosphorus-containing allenes with the derivatives of phosphorus of low coordination are investigated. The interaction of the l -vinyl-l-phosphoryloxy-3,3-di-methylallene with (dimethylaminomethylidene)phenylphosphine was shown to occur over 1,3-diene system according to Diels-Alder reaction. The formation of the six-membered heterocycle was accompanied by changing the coordination of the phosphorus atom from P^II to P^III. The reaction of the phosphorus containing 1,3-dipole (diethylaminobenzylidene)-aminodimethoxyphosphine with 1-vinyl-1-phosphoryloxy-3,3-dimethylallene was found to give the seven-membered aza-phosphepin. The changing of methoxy-radicals by ethoxy-groups in benzylideneaminophosphine leads to azaphos-phorins as products. The formation of the seven-membered adduct in this case is small. The two-step mechanism of these reactions with the initial attack of atom P at central carbon atom of allene is in agreement with kinetic, thermochemical and ³¹P-NBR data.     

Spatial characterization of the transversal structure of rotationally symmetric pulsed beams

A simple analytical model is proposed to describe the transversal spatial structure of a tridimensional rotationally symmetric pulsed beam. The spatial behaviour of the pulse amplitude is shown to be linked to its (measurable) second- and higher-order intensity moments, namely, beam width, quality parameter and kurtosis. As an illustrative experimental example, this model has been applied to high-quality TEA CO2 laser pulses. This revised version was published online in November 2006 with corrections to the Cover Date.     

A new method for the preparation of diphenylboryldipivaloyl phosphide

Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 11, pp. 2670–2671, November, 1990.     

Synthesis of C-(N,N-dialkylamino)phosphaalkenes

New C-(N,N-dialkylamino)phosphaalkenes were synthesized by the reaction of phenylphosphine with amidacetals. Such compounds may also be synthesized by the reaction of bis(trimethylsilyl)phenylphosphine with amidacetals.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 7, pp. 1639–1641, July, 1990.     

Highly unsaturated phosphorus compounds: Trimeric and dimeric sulfides of a α,β‐di‐tert‐butyl vinyl phosphaalkyne

The first examples of sulfides of a 1,3,5‐triphosphabenzene were synthesized by the sulfurization of parent 1,3,5‐triphosphabenzene 2 . Disulfide 7 was found to be remarkably thermally stable, the stability likely coming from the contribution of resonance forms 7A and 7B . In addition to two hydrolysis products of trisulfide 8 , which can be anticipated in unsaturated phosphorus chemistry, a new and not trivial bicyclic bridgehead five‐membered heterocycle 10 was isolated among the decomposition products of 8 . © 2010 Wiley Periodicals, Inc. Heteroatom Chem 22:114–118, 2011; View this article online at wileyonlinelibrary.com . DOI 10.1002/hc.20664     

Reaction of C,N-diphenylnitrone with N,N-dimethylaminomethylene-P-phenylphosphine

C,N-Diphenylnitrone oxidizes N,N-dimethylaminomethylene-P-phenylphosphine to give dioxophenylphosphorane and dimethylformamide and is reduced to benzalaniline.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 7, pp. 1641–1643, July, 1990.